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Job Description
Research Associate - Genomic safe harbour targeted engineering of cells for gene and cell therapy
Location: Cardiovascular-Metabolic Disease TRP, NUS YLL School of Medicine
Description:
We are a team headed by Dr Matias I Autio, Senior Research Fellow in the laboratory of Prof Roger Foo.
We are embarking on a project to establish genome-engineered packaging cell lines for production of lentiviral gene therapy vectors. The project is closely linked with industrial partners and the aim is develop technology with eventual commercial deployment.
We are looking for a Research Associate to drive the wet lab research activities for the duration of the project.
Responsibilities:
- Clone and amplify complex constructs necessary for engineering of mammalian cells
- Maintain cultures of mammalian cells to a high standard and conduct engineering experiments working closely with the project leads
- Compile and organise experimental data, including cell culture records, characterization results, and cell line inventory information
- Conduct daily wet-lab experiments e.g. nucleic acid extraction and quantification
- Assist the team to ensure a safe and efficient working environment
- Ensure project deliverables are met in a timely manner and to the highest standard
Qualifications
- Master’s Degree in Biology, Biochemistry, Molecular Biology, or related discipline.
- Minimum 3 years of working experience in a research laboratory
- Experience with mammalian cell culture and genome engineering
- Extensive knowledge of molecular cloning techniques
- Good organizational skills and ability to multitask
- Able to work independently and as part of a team
- Experience in working with lentiviral vectors is highly desirable
- Good communication (verbal and written)
This position offers an exciting opportunity to contribute to groundbreaking research in genome engineering for gene and cell therapy, with potential for career development and growth within our dynamic research environment.