The Senior Research Office/ Research Officer will oversee the progress of research studies under the Program for Nasopharyngeal Cancer with the supervision of the Principal investigator Dr Darren Lim. You will perform a variety of research activities which include planning and execution of experiments for biomarker discovery, novel diagnostics methods and drug development for Nasopharyngeal Cancer.
Your main duties will include:
1. Tissue Logistics:
- Tracking of biological samples received in the lab pertaining to the study
- Collection of patient samples (FFPE, Tissue, WBC, DNA or RNA) from Pathology
- DNA/RNA extraction from frozen tissue or FFPE
- Submission of DNA/RNA samples to external sequencing partner
2. Cell culture and Molecular assays:
- Generation of cell line and/or organoids from tissue collected for the study
- Maintenance of cell lines and/or organoids in culture
- Perform molecular assays on tissue samples /cell lines/ organoids
3. Perform tasks and support all aspects of the research project:
- Performing literature reviews when required
- Plan and execute experiments for the assigned studies
- Conduct accurate monitoring, documenting and reporting of experimental result and research findings
- Evaluate and interpret collected data and prepare oral presentations/scientific manuscripts/ literature for publication
- Lead and mentor junior staff in sample processing, experiments, data analysis, and database updates (Senior Research Officer)
4.Perform other related duties:
- Laboratory upkeep and maintenance
Requirements:
- Bachelor/Master of Science degree in related technical discipline (biology, cell biology, biomedical science, biochemistry or molecular biology).
- Prior experience with tissue and library prep for DNA/RNA sequencing studies.
- Experience working in a clinical or academic environment.
- Strong technical/wet lab skills.
- Team player with excellent communication skills and the ability to work independently.
- Independent worker, possess initiative to complete tasks and projects assigned.
- Highly motivated to learn new techniques and not afraid to ask if unsure.
- Able to undertake independent research progressively.
