Total 3 science rd research job vacancies in pas tiong bahru cc

As a Research Associate at Lucence, you will be part of a dynamic team and contribute to the development and optimisation of new genomic medicine technologies in our fight against cancer.

Your key responsibilities would include:

• Working closely with R&D team members to establish and maintain a reliable molecular diagnostic product pipeline that fills critical R&D goals at Lucence.
• Planning and executing laboratory molecular diagnostic experiments to implement new assays and improve current assays, including analytical and clinical validation of assays.
• Writing summary reports, contributing to scientific discussions and presenting technical data to achieve R&D objectives and to advance R&D efforts.
• Contributing to research-oriented projects for clinical validation of tests (in collaboration with external organizations).
• Maintaining workflows and writing standard protocols for performance of validated molecular diagnostic assays.
• Participating in knowledge and technology transfer to other technical sections of the company.
• Performing lab management duties including procurement and inventory management.
• Performing other relevant duties as assigned to further Lucence’s progress in R&D. This may also include authoring publications to share Lucence’s research and clinical findings.

To be a good fit for this role, you would have:

• At least a degree in Biomedical Science, Life Sciences or its equivalent.
• Familiarity with molecular biology techniques, including nucleic acid extraction, real-time PCR, molecular cloning, genotyping and NGS.
• At least 2 years of working experience in research and development is a plus, but not a necessity.
• The ability to work independently as well as in a team.
• Good communication and presentation skills and an ability to write short summary reports.
• Strong self-motivation, resilience, adaptability, and a keen interest in learning.

Lucence is a precision oncology company headquartered in Singapore that specializes in non-invasive early cancer detection. Operating dual laboratories in Singapore and Silicon Valley, Lucence is recognized as the first Asian-headquartered healthcare company to receive Medicare coverage.

Join us in bringing ultrasensitive early cancer detection to more people by being part of the team as a Research Scientist.

[Key Responsibilities]

• Drive development and automation of novel next-generation sequencing workflows or genomic medicine technologies.
• Propose, design, plan, execute, and interpret laboratory experiments to implement new molecular assays and improve current assays.
• Design, plan, and lead studies for analytical and clinical verification and validation.
• Author, review, and maintain internal workflows and protocols of validated molecular diagnostics assays.
• Analyse genomic data and publish/present work in peer-reviewed journals and international conferences.
• Collaborate closely with top-tier scientists, doctors, bioinformaticians and software engineers to develop new technologies and/or assays.

To be a good fit for this role, you would have:

• A PhD in Molecular Biology, Cancer Biology, Genomics, or related field.
• A proven track record of quick learning.
• Strong background in molecular biology, including PCR, RT-PCR, genotyping and NGS.
• At least 1 years of working experience in the development of molecular assays, with significant hands-on expertise in troubleshooting, implementing, and optimising assays.
• Strong self-motivation, resilience, adaptability, and a keen interest in learning. You will be working with world-class scientific and medical expertise, and be ready to be challenged every day.
• Excellent communication and presentation skills.

The following would be advantageous, but not required:

• A deep understanding and knowledge of oncology and/or genomics.
• Proficiency in R or Python.
• Experience in validation of NGS assays in a CLIA-compliant manner.
• Fluency in variant annotation and interpretation and use of genome databases such as COSMIC, ClinVar, Varsome, Ensembl, and OncoKB.
• Ability to interpret genomic data in patient- and treatment-specific contexts.
• Good track record of publications.

Specific title and responsibilities may be calibrated to match a given candidate’s experience.

Lucence is a precision oncology company committed to bringing clarity to cancer care. Lucence makes ultrasensitive non-invasive liquid biopsy tests to provide doctors and their patients life-changing information to enable earlier detection and effective treatment. Headquartered in Palo Alto and Singapore, Lucence supplies personalized cancer care services through twin CLIA-licensed laboratories in the United States and Singapore.

Key responsibilities:

· Based on an in-depth understanding of Lucence's technology and product portfolio and medical science, interpreting genomic alterations in appropriate clinical contexts and reporting (for both clinical and research samples) results accurately and timely following established procedures.

· Working closely with the Medical Data Science team in the curation and maintenance of database - evaluating scientific publications/clinical studies and integrating functional effects of genomic variants and their associated diseases using standard terminologies and established guidelines.

· Writing, maintaining, and updating workflows and protocols for clinical reporting pipeline.

· Participating in research-oriented projects for clinical validation of tests (in collaboration with external organizations).

· Participating in internal and external quality assurance programs.

· Performing other relevant duties as assigned.

To be a good fit for this role, you would have:

• At least a degree in Pharmaceutical Science, Biomedical Science, Life Sciences or its equivalent.

• Familiarity/good understanding in molecular techniques, genetics and NGS applications. Prior experience in research/clinical, in the field of cancer biology/genetics is a plus.

• Good communication and presentation skills and an ability to write short summary reports.

• The ability to work independently as well as in a team.

• Exceptional attention to detail.

• Flexibility in working on weekends, public holidays, from 8 am to 6 pm, based on staff rosters.

• Strong self-motivation, resilience, adaptability, and a keen interest in learning.

• COVID-19 Vaccination Requirement: Fully Vaccinated.

The following will also be a plus:

• Knowledge in genomic medicine and liquid biopsy; and

• Fluency in variant annotation and interpretation and use of genome databases such as COSMIC, ClinVar, Varsome, Ensembl and OncoKB; and

• Ability to interpret genomic data in patient- and treatment-specific contexts following established procedures.

Please send your CV to [email protected] indicating the position you are applying for in the subject line. In addition, get creative and tell us in the email in less than 100 words (in any language you like) why you think you will be a right fit for Lucence. Don't limit yourself to a job description or job title, the world needs every skill you have.