A Research Fellow position in enzyme engineering/synthetic biology for CNegSAF project is available at the Campus for Research Excellence and Technological Enterprise (CREATE) in Singapore.
CNegSAF PROJECT
CNegSAF Project: Carbon Negative production of advanced Sustainable Aviation Fuels using twin synthetic bacterial consortia
Hosted by CNRS@CREATE, the program ‘Carbon Negative production of advanced Sustainable Aviation Fuels using twin synthetic bacterial consortia Project’ (CNegSAF) is an international collaboration between world leading institutions in France and Singapore including CNRS, Toulouse Biotechnology Institute (TBI), National University of Singapore, A*Star (SIFBI), and Nanyang Technological University. CNegSAF aims to demonstrate the feasibility of using a synthetic bacterial consortium to convert green hydrogen and concentrated waste CO2 (released by chemicals companies) into sustainable aviation biofuels. This innovative research program has the potential to significantly contribute to Singapore’s and the world net-zero emissions target while supplying sustainable aviation fuels to the aviation industry.
Read more about the CNegSAF project here.
DESCRIPTION
To join this team, we are looking for a candidate who will be in charge of enzyme engineering activities using state-of-the-art evolutionary engineering and computational enzyme design techniques. The candidate will be involved in the development of screening protocols, construction and screening of enzyme libraries, designed by in silico molecular modelling. These enzymes will be further used for the creation of novel metabolic pathways for terpenoid production in engineered bacterial strains.
The perspective researcher will work in a multidisciplinary environment with access to high-throughput screening equipments (both in Singapore and Toulouse, France) and have frequent and strong interactions with other scientists involved in metabolic engineering, pathway engineering and computational enzyme design.
EXPERIENCE & QUALIFICATIONS
• PhD in Molecular Biology, Biochemistry, Biochemical engineering or related field
• Experience with enzyme engineering and enzyme library construction
• Expertise with HT screening, assay design and development and trouble shooting
• Experience in structural biology and molecular modelling/computational enzyme design would be a plus
• Preferred experience with protein production, purification, characterization and crystallization knowledge
• Preferred experience with metabolic engineering/synthetic biology background
• Strong communication with structured reporting and organizational skills
• enjoy working in a team-oriented environment
• Good English skills are required.
FURTHER INFORMATION & CONTACT
Salary range: SGD 6,900 – SGD 10,000 (depending on suitability and experience)
The position is available starting February 2025 and for a duration of up to three years. The position will be mainly based in Singapore with possible visiting stays in Toulouse, France.
Applicants should send as soon as possible CV, summary of previous research and contact addresses of two references to:
Isabelle ANDRÉ (TBI, Toulouse, France): [email protected]
Xixian CHEN (A*-SIFBI, Singapore) : [email protected]
Bo XUE (SynCTI-NUS, Singapore): [email protected]
Thomas Lautier (TBI, Toulouse, France): [email protected]