Job description: Research Scientist, Chemical Development: Linker-payload synthesis for Antibody Drug Conjugates (ADCs):

• Engage in groundbreaking research and development in the field of synthetic organic chemistry, peptide chemistry.
• Investigate and explore new ideas and concepts by defining experiments in order to verify proof of principle.
• Collaborate with biologists constantly to develop novel linker-payloads for next generation Antibody-Drug Conjugates
• Collaborate closely with project team members and other cross-functional groups in the organization.
• Submit and present project updates and reports in verbal and written formats.
• Write invention disclosures and possible patent applications.
• Manage and prioritize daily assignments to ensure timely completion.
• Attend and participate in scheduled planning meetings and/or status meetings.
• Manage and maintain required reagents, laboratory environment, and equipment needed to carry out assignments.
• Adhere to safety and regulatory requirements
• Transfer new products from R&D to Manufacturing.
• Responsible for sustaining products to address customer needs
• Writing SOP and work instruction according to Quality management standards and requirements.
• Other opportunities may include possible contributions to scientific literature and presentations at conferences.

Requirements

• PhD in synthetic organic chemistry with 5 years relevant experience.
• R&D experience in multi-step small molecule synthesis, peptide synthesis
• Proficient in operating analytical equipment and applying analytical chemistry principles
• Experience with new product development is a plus
• Strong understanding of instrumentation principles and troubleshooting ability.
• Strong understanding of synthetic chemistry
• Strong understanding of Analytical chemistry principles
• Record of accomplishment should be demonstrated by publications or patents
• Demonstrated organizational skills with the ability to balance multiple tasks with different priorities
• Ability to make independent decisions and possess strong initiative
• Ability to dissect problems with strong analytical and critical thinking skills
• Ability to accurately plan, define, and manage projects tasks
• Must possess excellent verbal and written communication skills.
• Capable of working with multi-disciplinary teams.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to study the metabolic regulation of immune cells during the NASH to NASH-HCC progression.

Metabolic regulation of immune dysfunction during the progression of NASH to NASH-HCC

Description:

The lack of effective treatments for non-alcoholic steatohepatitis (NASH) and NASH-associated hepatocellular carcinoma (NASH-HCC) underscores the need to understand the transition from NASH to NASH-HCC. Identifying why some NASH patients develop HCC while others do not is a significant challenge, with growing evidence indicating that immune dysregulation plays a crucial role in this progression. The interstitial space, where cells receive nutrients and signals, significantly impacts immune function, suggesting that understanding the liver"s metabolic environment could reveal how immune cells behave during NASH progression to HCC. By profiling interstitial fluid metabolism and single-cell transcriptomics, the team aims to understand the metabolic regulation of the immune landscape in NASH to NASH-HCC progression. Using a high-fat, high-fructose, and high-cholesterol dietary mouse model that mirrors human progression, the team will study the metabolic and immune changes leading to NASH-HCC. In addition, the team’s preliminary findings show immune alterations and reduced levels of the bile acid hyodeoxycholic acid (HDCA) during NASH-HCC transition. The identified candidate will also test the potential of HDCA in preventing NASH to HCC transition, and further explore HDCA"s effects on immune cells.

Job responsibilities:

• Conduct in vitro wet lab experiments (e.g. cell culture, molecular biology and assays, microscopy etc)
• Conduct in vivo animal experiments (e.g. diet/treatment regimes, body weight & composition analyses, metabolic phenotyping, blood sampling etc)
• Conduct end-point animal experiments (e.g. terminal blood collection, tissue collection and sample preparation, whole tissue/organ imaging, serum measurements etc)
• Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings
• Interact and collaborate with and assist other researchers and collaborators on related projects
• Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction
• Assist in the preparation of grant applications and grant process reports
• Present findings both orally and in written form via presentations and publication in peer-reviewed journal
• Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals
• Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with experience in dermatology, immunology, molecular allergy and clinical immunology
• At least 2 years experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• 1-2 years of experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Tower Research Capital, a high-frequency proprietary trading firm founded in 1998, seeks a Risk Manager, with a strong background in systematic/algorithmic trading to join the global Risk and Trading Supervision team in Singapore.

Responsibilities

• Providing risk oversight for the APAC trading activities of the firm by focusing on electronic trading risk and market risk
• Support the APAC Head of Risk in developing and enhancing risk management framework, policies and procedures
• Controlling both electronic trading risk and market risk of strategies in real-time, and consequently escalating, reporting, and resolving any risk related issues in a timely manner
• Working closely with the Portfolio Managers, Traders, Core Engineering team, and Exchanges/Prime Brokers to respond effectively to any risk limit violation and resolving any trading and risk related issues
• Assisting Risk Management and Risk Technology teams to enhance the electronic trading risk controls and design the next generation of risk analytics and trading supervision systems
• Conducting ad-hoc risk analysis and back-testing on trading strategies on a regular basis

Qualifications

• Bachelor’s degree in Financial Engineering, Mathematics, Economics, Computing or related field. Quantitative Master’s degree highly regarded
• At least 5 years of experience in an electronic trading role gained from a quantitative proprietary trading group, systematic hedge fund manager, or sell-side electronic trading role
• Strong experience with algorithmic trading and low latency electronic risk controls is preferred
• Strong financial markets, products and valuation knowledge preferably in Equities, FX and related derivatives (futures and options)
• Understanding of regional exchange-specific rules and regulations
• Strong Python and database proficiency skills in conducting data and quantitative analysis
• Good track record of working with senior management, compliance, business management and technology teams
• Strong problem-solving skills, attention to details with excellent written and verbal skills
• Desire to continuously learn and proactively challenge the status quo to improve existing processes

Please apply here: https://talent.sage.hr/jobs/12fc69c2-7012-4edc-b214-bb9c2ded1da2

Applicants will need to include a Cover Letter and CV with publication list.

Applications will be reviewed on a rolling basis, with final submission 20 January 2025.

We are particularly looking for IC Design Research Engineers with the following backgrounds:

- Digital IC Design

- Analog IC Design

As an IC Design Research Engineer, you will design and innovate secure circuits and systems for next-generation low-power IoMT devices and sensors, focusing on hardware security, and smart computing and connectivity platforms.

Imperial College London and Nanyang Technological University (NTU) are seeking Research Engineers and Research Fellows to join the exciting new Imperial/NTU CYber Protection for HEalthcaRe (IN-CYPHER) research programme on the cybersecurity of connected medical devices and systems.

The successful candidates will join the research programme which represents a collaboration between the United Kingdom and Singapore and will be based at the newly established Imperial Global Singapore (IGS) housed within the unique CREATE campus.

Positions will be initially for 2 years fixed term (subject to 6-month probation) with potential for extension.

Informal enquiries are greatly welcome. You are encouraged to send an e-mail to Dr Viktor Schlegel, Deputy Programme Director [email protected], together with an indication of the specific position you would like to apply for.

Questions about the recruitment process, should go to Paige Noyce, Associate Director [email protected].

Positions are based in Singapore at Imperial Global Singapore at the National Research Foundations Campus for Research Excellence and Technological Enterprise (CREATE) located on the campus of the National University of Singapore.

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 5 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 2 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 2 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 5 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Key Responsibilities:

• Provide scientific and technical expertise to lead a research team to develop capabilities in ingredient fermentation
• Develop mechanistic understanding of the microbiology of fermentation
• Develop research proposals and seek research fundings
• Disseminate research findings through conference presentations and journal publications
• Build and maintain strong relationships with local and international research network

Job Requirements:

• Possess a PhD degree in microbiology, fermentation or relevant disciplines
• Excellent knowledge and experience in microbiology and food fermentation
• At least 5 year of independent research experience and leading a research team
• Strong supervisory skills
• Strong track record for securing research funding
• Excellent publication track record
• Excellent communication and interpersonal skills, with the ability to effectively engage with diverse stakeholders at all levels
• Track record of strategic thinking capability with a outcomes-oriented mindset, able to translate vision into actionable plans and driving their execution

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub).

The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 3+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub). The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 5+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• At least a minimum of 5 years of relevant experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to identify and validate candidates that address the body’s adaptive responses to weight loss.

TaRgeted Analysis of Novel Secreted Factors for Obesity Reduction and Metabolic Health (TRANSFORM)

Description:

Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g. mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies and therapeutic strategies.

Job responsibilities:

● Conduct in vitro wet lab experiments for identified candidates (e.g. cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy etc)

● Conduct in vivo screening experiments for prioritized candidates (e.g. in preclinical models of obesity)

● Conduct end-point and mechanistic experiments (e.g. target tissue and blood collection, sample preparation etc)

● Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings

● Interact and collaborate with and assist other researchers and collaborators on related projects

● Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction

● Assist in the preparation of grant applications and grant process reports

● Present findings both orally and in written form via presentations and publication in peer-reviewed journal

● Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals

● Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

A Trainee Ship Broker for cape size is responsible for many stages of setting up and negotiating deals, including presenting the business to potential clients, negotiating the main terms of a contract or sale and seeing it through to its conclusion and any follow up that may be involved.

Duties and responsibilities

· Develop a framework and processes to manage chartering business.

. Oversee negotiations relating to ship chartering. Work closely with traders and attend to their queries, looking for cooperation with trader directly.

· Negotiate charter party terms and conditions on behalf of Owners or Charterers.

· Provide timely and accurate shipping information, voyage calculations to trading teams to facilitate smooth trading activities.

· Excellent communicational skills are required to liaise with ship owners, cargo owners, ship brokers etc.

· Capability to work under pressure

· Self-motivated and a team player

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in dermatology, immunology, molecular allergy and clinical immunology
• Experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description & Requirements

A Ship Broker is responsible for many stages of setting up and negotiating deals, including presenting the business to potential clients, negotiating the main terms of a contract or sale, and seeing it through to its conclusion and any follow-up that may be involved.

Duties and responsibilities

·Develop a framework and processes to manage chartering business

·Oversee negotiations relating to ship chartering. Work closely with traders and attend to their queries, looking for cooperation with traders directly.

· Negotiate charter party terms and conditions on behalf of Owners or Charterers.

· Provide timely and accurate shipping information, voyage calculations to trading teams to facilitate smooth trading activities.

· Excellent communicational skills are required to liaise with ship owners, cargo owners, shipbrokers etc.

· Capability to work under pressure

· Self-motivated and a team player

A Ship Broker is responsible for many stages of setting up and negotiating deals, including presenting the business to potential clients, negotiating the main terms of a contract or sale and seeing it through to its conclusion and any follow up that may be involved.

Duties and responsibilities

· Develop a framework and processes to manage chartering business.

. Oversee negotiations relating to ship chartering. Work closely with traders and attend to their queries, looking for cooperation with trader directly.

· Negotiate charter party terms and conditions on behalf of Owners or Charterers.

· Provide timely and accurate shipping information, voyage calculations to trading teams to facilitate smooth trading activities.

· Excellent communicational skills are required to liaise with ship owners, cargo owners, ship brokers etc.

· Capability to work under pressure

· Self-motivated and a team player

The Trianee Forward Freight Broker is responsible for executing research on shipments and determining the divergences of the freight, fulfill any research related enquiries the Brokers may have or request for and other ad-hoc tasks.

• Monitor and stay up to date with factors such as the Baltic Index, fuel costs, cost of insurance etc.
• Perform and deliver an analysis for Market Supply & Demand Model with data collected.
• Maintain, update and refine the Freight Matrix to be distributed to clients.
• Work on the maintenance and development of various models and new products relating to international trade and the demand for shipping.
• Supporting senior team members in preparing presentations that are delivered to key clients.
• Providing general assistance to the Dry Market Analysis team and brokers with a variety of ad-hoc analytical requests.
• Education – Bachelor’s Degree in the Maritime Business / Data Science
• Specialized knowledge (Preferred)
  • Data Analysis
  • Computer Literacy (Proficient in MS Excel, PowerPoint, Word)Abilities
  • Outspoken
  • Good customer relations skills
  • Able to remain calm and deliver under pressure and tight deadlines
  • Other characteristics such as personal characteristics
  • Independent

Please apply here: https://talent.sage.hr/jobs/8e073ef4-d42b-4457-a8d7-d0d491627bad

Applicants will need to include a Cover Letter and CV with publication list.

Applications will be reviewed on a rolling basis, with final submission 20 January 2025.

We are particularly looking for Wet Lab Specialists with the following backgrounds:

- Biomedical sensor design and fabrication

- Electrochemistry

- Biomedical Engineering

- Wet lab experience with regard to protein and small molecule assays

- Translational and regulatory expertise in medical devices

As a Wet Lab Specialist, the successful candidate will contribute to the programme by developing novel biosensors that are secure by design, and work toward translating the devices into clinical practice to drive the future of personalised medicine.

Imperial College London and Nanyang Technological University (NTU) are seeking Research Engineers and Research Fellows to join the exciting new Imperial/NTU CYber Protection for HEalthcaRe (IN-CYPHER) research programme on the cybersecurity of connected medical devices and systems.

The successful candidates will join the research programme which represents a collaboration between the United Kingdom and Singapore and will be based at the newly established Imperial Global Singapore (IGS) housed within the unique CREATE campus.

Positions will be initially for 2 years fixed term (subject to 6-month probation) with potential for extension.

Informal enquiries are greatly welcome. You are encouraged to send an e-mail to Dr Viktor Schlegel, Deputy Programme Director [email protected], together with an indication of the specific position you would like to apply for.

Questions about the recruitment process, should go to Paige Noyce, Associate Director [email protected].

Positions are based in Singapore at Imperial Global Singapore at the National Research Foundations Campus for Research Excellence and Technological Enterprise (CREATE) located on the campus of the National University of Singapore.