The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub).

The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 3+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub). The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 5+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• At least a minimum of 5 years of relevant experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to identify and validate candidates that address the body’s adaptive responses to weight loss.

TaRgeted Analysis of Novel Secreted Factors for Obesity Reduction and Metabolic Health (TRANSFORM)

Description:

Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g. mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies and therapeutic strategies.

Job responsibilities:

● Conduct in vitro wet lab experiments for identified candidates (e.g. cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy etc)

● Conduct in vivo screening experiments for prioritized candidates (e.g. in preclinical models of obesity)

● Conduct end-point and mechanistic experiments (e.g. target tissue and blood collection, sample preparation etc)

● Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings

● Interact and collaborate with and assist other researchers and collaborators on related projects

● Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction

● Assist in the preparation of grant applications and grant process reports

● Present findings both orally and in written form via presentations and publication in peer-reviewed journal

● Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals

● Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in dermatology, immunology, molecular allergy and clinical immunology
• Experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description

We are looking for talented wet-lab Research Fellow to work with a multidisciplinary group of scientists on the discovery of new targets for therapy in Diabetic Nephropathy (DN), a devastating complication of diabetes causing significant morbidity, mortality and human suffering. In Singapore, the incidence of DN as a cause of end-stage kidney disease is among the highest in the world. The job will be part of the NMRC-funded project called Diabetes Study in Nephropathy and other Microvascular Complications II, and it will be based within the Centre for Computational Biology (CCB). This position will be for a period of 3 years, with possible extension depending on work performance and funding availability.

The selected candidate will perform a variety of research activities, which include planning, organising and conducting research studies within the overall scope of a research project under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Contribute to occasional educational / instructional activities and project management.
• Provide guidance and mentorship to undergraduate / medical students and research assistants.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in a related scientific area (e.g., Life Sciences/Biomedical Sciences, Pharmacology). Candidates with higher credentials may be considered for Senior Research Fellow appointment.
• Hands-on experience with transgenic models (breeding and maintenance) and surgery.
• Experience with rodents (mice/rats) phenotyping, including metabolic traits, biochemistry, histology and microscopy.
• Hands-on experience with wet-lab techniques in molecular and cell biology, including familiarity with primary cell cultures and inflammatory and metabolic cellular assays.
• Possess knowledge and experience in pharmacology and pharmacokinetics.
• Have a system-level understanding of human cardiometabolic pathology.
• Proven track record in the form of peer-reviewed research publications.
• Demonstrated capability of research independence progressively.
• Possess strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will play a key role in a natural products-based drug discovery program, conducting analytical chemistry, bioassays, compound management, molecular and cell biology, and biochemistry laboratory experiments under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Support all aspects of the research project.
• Conduct extractions and fractionation of natural products.
• Execute cancer and other mammalian cell culture assays.
• Carry out antibacterial and antifungal assays and assist with microscopy imaging of cells.
• Perform molecular and phenotypic analyses to understand mechanism of action.
• Conduct accurate monitoring, documenting and reporting of experimental results and/or research findings.
• Assist with general upkeep of laboratory needs, procurement of reagents, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described therein.

Job Requirements

• Bachelor’s or Master’s Degree in Analytical Chemistry, Chemical Biology, Pharmacology, or other related fields. Candidates with higher credentials may be considered for the Research Assistant (Senior) position.
• Familiar with organic and analytical chemistry techniques, including chromatography and HPLC.
• Demonstrated knowledge and possesses experience in cell and molecular biology techniques such as cell culture, western blot, RNA and DNA isolation, and RT-qPCR.
• Strong interpersonal communication skills with excellent written, and computer skills.
• Well-organised and excellent record keeping skills are a must.
• A strong team player who is open-minded, energetic, highly motivated and can work collaboratively in an interdisciplinary team and diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will play a key role in a natural products-based drug discovery program. He/she will work both independently and collaboratively to analyse complex natural products using NMR and mass spectrometry, including metabolomic profiling to identify potential molecular targets and mechanisms.

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Source financial support for research activities by investigating potential sources of funding, collaborate with Principal Investigator to write and revise grant/fellowship applications.
• Provide guidance and mentorship to junior researchers.
• Ensure optimal progress of experiments in the laboratory by conducting, supervising, and evaluating laboratory procedures and outcomes. Revise and analyse targets to obtain high-quality and reproducible results.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in Chemistry, Chemical Biology, or related discipline with 2 years of relevant post-doctoral experience.
• Demonstrate general expertise in the field of natural products isolation, metabolomics, and global profiling.
• Strong NMR and mass spectrometry skills in compound characterisation.
• Familiar with database and networking platforms for dereplication (e.g., GNPS).
• Proven track record in the form of high impact publications.
• Strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Cardiovascular and Metabolic Disorders (CVMD) Programme at Duke-NUS houses state-of-the-art technologies for profiling mitochondrial function and metabolic adaptations in model organisms and undertakes translational research in cardiovascular and metabolic disorders. The program has a strong track record of publication in top-tier journals, successful commercialisation efforts leading to spin-offs, as well as nurturing early career researchers into independent academic or industry positions.

Metabolic dysfunction-associated steatohepatitis (MASH) is a severe metabolic liver disease that can affect up to 6.5% of the adult population, with only one FDA-approved drug. Dr. Jin Zhou’s team is specialised in studying the novel molecular pathogenesis underlying MASH for the identification of new druggable targets. The lab uses a combination of biochemistry, genetics, animal modeling, and metabolomics approaches to understand cellular processes related to mitochondrial function and hepatic lipid metabolism.

We are looking for a highly self-motivated Research Fellow to join the team. The selected candidate will perform a variety of research activities, including but not limited to the following:

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Maintain accurate and complete records of all findings and ensure the validity and reliability of data at all times.
• Present research outcomes orally, and draft research abstracts and manuscripts for publication.
• Provide guidance and mentorship to undergraduate/medical students and research assistants.
• Perform other related duties incidental to the work described herein.

Job Requirements

• PhD in Biomedical Sciences, Molecular Biology, Cell Biology, Pharmacology, or related disciplines.
• Hands-on experience with mice models, as well as wet-lab techniques in molecular and cell biology. Prior experience in polysome and/or ribosome profiling would be advantageous.
• Proven track record of academic publications, including writing/drafting first-author papers.
• Demonstrate excellent communication, technical independence, and analytical and problem-solving skills.
• Self-motivated individual, enthusiastic to take initiative, and able to work independently and collaboratively in a team.

We regret that only shortlisted candidates will be notified.

Job Description

The laboratory of Dr. Tang Hong-Wen within the Signature Research Programme in Cancer and Stem Cell Biology (CSCB) at Duke-NUS is recruiting a Research Assistant with strong enthusiasm and interest in muscles and muscle stem cells. The Tang lab’s scientific focus is to understand how muscle functions get impaired during aging and tumorigenesis. Dr Tang’s laboratory uses unique cross-species and interdisciplinary approach incorporating Drosophila genetics, biochemistry, cell biology, and mouse models, to identify new evolutionary conserved mechanisms underlying human muscle diseases and provide new therapeutic strategies targeting muscle wasting and mitigating the effects of aging.

The selected candidate will perform a variety of functions related to research under the supervision of the Principal Investigator or his/her designate: -

• Perform tasks and support all aspects of the research project.
• Conduct accurate monitoring, documenting and reporting of experimental results and research findings.
• Evaluate and interpret collected data and prepare oral presentations or written reports/ scientific manuscripts/literature for publication and analyses setting forth progress, adverse trends and appropriate recommendations or conclusions.
• Contribute to some project management, provision of guidance to undergraduate/medical students.
• Assist with general upkeep of laboratory needs, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described herein.

Job Requirements

• Bachelor’s Degree in Sciences / Life Sciences.
• Demonstrated basic knowledge, skills and expertise in supporting various research activities.
• Knowledge of the scientific background relevant to the research area.
• Laboratory experimental skills.
• A strong team player who is open-minded, energetic, highly motivated and can work collaboratively in an interdisciplinary team and diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Laboratory for Translational and Molecular Imaging (LTMI), Duke-NUS Medical School, is recruiting a Research Fellow/Senior Research Fellow to lead state-of-the-art small animal imaging studies in Viral Infectious Disease. LTMI aims to develop local infrastructure and deep capabilities in the development of molecular imaging technologies for guiding the advancement and translation of new imaging biomarkers to guide novel therapeutics in viral infectious disease.

The successful candidate will lead pre-clinical imaging efforts to validate novel imaging probes that target potential biomarkers of viral infection and host response. He/She will be responsible for the strategic planning, execution and communication of research. Candidates with strong records of scientific accomplishment in radiopharmaceutical sciences, immunology or related disciplines are encouraged to apply.

Lead mouse model development and characterisation of viral disease.

• Perform in vivo characterisation of imaging probe specificity and sensitivity with PET/CT, SPECT/CT and/or optical imaging in combination with different treatment regimes.
• Monitor immune response to anti-viral, and vaccines with longitudinal imaging, supported with pathology (IHC/IF), and cellular assessment (flow cytometry).
• Ensure regulatory compliance of research, including legal and ethical requirements.
• Ensure timely reporting and presentation of study results to the team, and making appropriate decisions on data obtained from imaging studies.
• Write and review research papers, and present at local and international conferences.
• Provide guidance and mentorship to junior researchers and/or graduate students.
• Demonstrate effective organization/project management abilities to efficiently manage time and work activities.

Job Requirements

• PhD in Virology/Immunology/Radiopharmaceutical Sciences or related disciplines.
• Experience in multimodality imaging and image analysis (including PET, SPECT, CT, fluorescence, and/or optical imaging) within the infectious diseases and immunology domain.
• Background in virology, molecular biology, cell biology and oncology.
• Possesses experience in mouse studies (injection, anatomy, necropsy, pathology) required.
• Proven track record of academic publications, including writing/drafting first author papers.
• Self-motivated individual, enthusiastic to take initiatives, as well as able to work independently and collaboratively in a team.
• Demonstrate excellent communication, technical independence, analytical and problem-solving skills.

We regret that only shortlisted candidates will be notified.

Job Description

The Cardiovascular and Metabolic Disorders (CVMD) Programme houses state-of-the-art technologies for profiling mitochondrial function and metabolic adaptations in human patients and other model organisms, and undertakes translational and clinical research in cardiovascular and metabolic disorders.

Prof Derek Hausenloy’s laboratory aims to discover new treatments for protecting the heart from acute ischaemia/reperfusion injury and for preventing heart failure. We use a translational approach to research comprising cell models, rodent models (atherosclerosis, acute myocardial infarction and heart failure), nanoparticles for delivery of therapeutics to the ischaemic heart, and clinical studies.

The selected candidate will perform a variety of functions related to research under the supervision of the Principal Investigator or his/her designate, including but not limited to the following: -

• Perform tasks and support all aspects of the research project.
• Conduct accurate monitoring, documenting and reporting of experimental results and/or research findings.
• Evaluate and interpret collected data and prepare oral presentations or written reports/ scientific manuscripts/literature for publication and analyses setting forth progress, adverse trends and appropriate recommendations or conclusions.
• Assist researchers in contributing to some aspects of the project management, occasional laboratory demonstrations and in providing guidance to undergraduate/medical students.
• Establish work procedures to maintain high efficiency and productivity of the laboratory. Assist with general upkeep of laboratory needs, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described herein.

Job Requirements

• Bachelor / Master’s Degree in Sciences/Life Sciences with at least 2 years of relevant work experience in the design and conduct of experimental projects.
• Demonstrated good knowledge, skills and expertise in supporting various research activities including molecular biology, cellular assay, ELISA, and histology.
• Knowledge of the scientific background relevant to the research area.
• Laboratory experimental skills.
• Experience with cardiovascular research and animal work (rodents) preferred.
• A strong team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.
• RCULA certification will be an advantage.

We regret that only shortlisted candidates will be notified.

As the Research Engineer (Equipment/Operations), you are directly involved in tool installation activities for semiconductor process tools. You would need to work proactively to coordinate with the contractor on the ground for the execution and take corrective and preventive actions of lessons learned, due diligently to prevent reoccurrence. You are responsible for performing utilities turn-on after installation is completed. You must perform the activities per ASTAR site procedure and safety policies to ensure all tool-install-related activities are completed, meeting safety, quality, schedule and budget requirements. You will also be required to perform other activities such as operations for the different semiconductor modules (Diffusion, Litho, Dry/Wet Etch, Thin Film, Implant, etc).

Responsibilities:

• Coordinate with all tool-install base contractors to execute equipment hookup for new tools, to meet the high-quality standards, dynamic schedule, and forecasted budget.
• Coordinate with the Project owner (NGTC/APM) to facilitate utility release as per the planned schedule and update tool release status timely
• Follow all safety and environmental procedures to ensure compliance with EHS-related regulations, risk assessment, safe work procedures, and permit-to-work system.
• Play an active role in safety, actively participating in safety discussions and safe work practices.
• Establish regular area walks to identify opportunities for improved safety, cleanliness, housekeeping and efficiency
• Establish regular, working interaction with peers as well as vendors in tool installation & facilitation, communicating clearly and respectfully all relevant information.
• Keep the reporting officer informed regarding the progress of assigned work and any abnormalities observed in your area.
• Demonstrate ability to understand drawing and highlighting discrepancies
• Follow area-specific procedures and documentation
• Prioritize work tasks to meet schedule and expectations, minimum guidance
• Perform tool tool-relativities and cleanroom systems troubleshooting during the hookup phase
• To perform equipment trouble-shooting of the equipments in NGTC when the need arises
• To perform utility-on after installation completion and to work closely with LCAM for complete closure
• To perform tests balancing of exhaust for new tools whenever necessary
• To perform measures for tool consumption during the hookup phase and to work closely with LCAM
• Use methods to organize, calculate, and display data accurately for utility and flowrate measurement
• Perform site activities in accordance to the Discipline

Requirements:

• Degree/Diploma in Mechanical/Electrical/Chemical engineering or equivalent
• Semiconductor experience (Equipment & Process)
• Facilities field or Wafer Fab Manufacturing equipment background will be an advantage.
• AutoCAD

Job Description:

• Actively working with cross functional stakeholders to plan and develop new lithography process
• Validate mask designs, reticle tape out and post tape out verifications
• Actively participate in internal and external technical discussions to overcome process related challenges and provide relevant solutions
• Perform process characterization, margin study to determine the process capability of new process platform
• Act as subject matter expert and resource for researchers and industry partners to enable process and/or product realization
• Publish process development outcomes and breakthroughs in research community
• Engage with relevant equipment makers/vendors and responsible for selecting and procuring research equipment
• Work with fab team in establishing SPC for newly developed processes

Job Requirements:

• Bachelors/Masters in Materials Science and Engineering, Physics, Electrical Engineering, or closely related fields are welcome to apply
• More than 5 years of relevant working experience in R&D and/or industry environment and broad exposure in handling 6”, 8” and/or 12” substrate covering nano to micron technology nodes, preferably in SiC/GaN/Photonics
• Proficient in Photolithography tools including Immersion/KrF/I-line Scanner/Stepper/Mask Aligner, knowledge in eBeam Lithography tool will be added advantage
• Hands-on experience in metrology including but not limited to CdSEM, Overlay, OCD, DRSEM, Microscope. Capable to create recipe to support various research requirements
• Knowledge in design and simulation (ProLith, OPC,etc), and reticle layouts (OAS,GDS) review and basic tape out process
• Equipped with Photolithography skill set including fundamental lithography theory, Photoresist characteristic and application, new process setup (swing curve, FEM, DoE, Statistic Root Cause Analysis and problem solving methodology, etc), optimization and margin improvement.
• Relevant hardware and application knowledge in Photolithography tools and metrology.
• Possess good interpersonal and oral/written communication skills, with ability to deliver clear and concise messages to both internal and external stakeholders.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The National University of Singapore invites applications for the position of Research Assistant in the Department of Information Systems and Analytics, School of Computing. The School of Computing is strongly committed to research excellence in all its dimensions: Searching for fundamental results and insights, developing novel computational solutions to a wide range of applications, building large-scale experimental systems and improving the well-being of society. We seek to play an active role both internationally and locally in the core and emerging areas of Computer Science and Information Systems.

The Research Assistant will be responsible for working closely with the Principal Investigator and lab members on one or more research projects. He/she should possess experience or interest in at least one of the following research areas:

Key responsibilities:

• Build a tree based private blockchain system for the given specification. It is a tree structure with hash based dependency for validation similar to blockchain.
• Evaluate the tree based system for efficiency, accuracy, scalability, throughput and energy efficiency through simulations with varying data complexities.
• Build an application using the tree based structure and gather insights from users, developers or businesses leveraging BlockForest, focusing on ease of usage/integration and practical benefits.

Only shortlisted candidates will be notified.

Job Requirements

• A Bachelor’s degree with Honours in Computer Science or related area;
• Good knowledge in Blockchain technologies; and
• Experience in research

Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, and other new antibody engineering technologies that are under development.

Research Assistant – Mid-size Molecule Unit

Job Scope:

· Peptide screening - ELISA, bead-based separation etc.

· DNA/RNA analysis - primer design, PCR, qPCR, purification (spin column, magnetic beads, ethanol precipitation, phenol chloroform extraction etc.), electrophoresis (Agarose gel, Urea-PAGE), NGS(Illumina) etc.

· Protein analysis - SDS-PAGE, western blotting, ELISA etc.

Requirements

· Lead identification screening in drug discovery

· Antibody, protein or peptide engineering

· Biopanning, such as phage display, SELEX, in vitro compartmentalization, microfluidics

· RNA-related analytics, protein purification, NGS data analysis, Biomek operation, etc.

· Degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Molecular Biotechnology with 1-2 years of working experience in a related field.

· Fresh graduates are welcome to apply.

Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to: [email protected]

For more information regarding our Company, you may refer to our website at:

http://chugai-pharmabody.com/

We regret that only short-listed candidates will be notified

Job Description:

• Actively working with cross functional stakeholders to plan and develop new lithography process
• Validate mask designs, reticle tape out and post tape out verifications
• Actively participate in internal and external technical discussions to overcome process related challenges and provide relevant solutions
• Perform process characterization, margin study to determine the process capability of new process platform
• Act as subject matter expert and resource for researchers and industry partners to enable process and/or product realization
• Publish process development outcomes and breakthroughs in research community
• Engage with relevant equipment makers/vendors and responsible for selecting and procuring research equipment
• Work with fab team in establishing SPC for newly developed processes

Job Requirements:

• Bachelors/Masters in Materials Science and Engineering, Physics, Electrical Engineering, or closely related fields are welcome to apply
• More than 5 years of relevant working experience in R&D and/or industry environment and broad exposure in handling 6”, 8” and/or 12” substrate covering nano to micron technology nodes, preferably in SiC/GaN/Photonics
• Proficient in Photolithography tools including Immersion/KrF/I-line Scanner/Stepper/Mask Aligner, knowledge in eBeam Lithography tool will be added advantage
• Hands-on experience in metrology including but not limited to CdSEM, Overlay, OCD, DRSEM, Microscope. Capable to create recipe to support various research requirements
• Knowledge in design and simulation (ProLith, OPC,etc), and reticle layouts (OAS,GDS) review and basic tape out process
• Equipped with Photolithography skill set including fundamental lithography theory, Photoresist characteristic and application, new process setup (swing curve, FEM, DoE, Statistic Root Cause Analysis and problem solving methodology, etc), optimization and margin improvement.
• Relevant hardware and application knowledge in Photolithography tools and metrology.
• Possess good interpersonal and oral/written communication skills, with ability to deliver clear and concise messages to both internal and external stakeholders.

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking a Laboratory Officer/ Technician (BSL-3 operations) to join us. The Laboratory Officer/ Technician will engage in day-to-day operations, housekeeping, maintenance of the high containment (BSL-3) and BSL-2 enhanced laboratories. This role will involve but is not limited to the following:

Job Responsibilities:

• Perform lab biohazard waste collection, sort, autoclave, and safe disposal.
• Liaise with biohazard waste contractor for scheduled disposal.
• Manage laboratory supplies, chemical and equipment inventory.
• Assist in coordination of the lab maintenance, calibration, repair of faulty and recertification of laboratory equipment.
• Coordinate with vendors and service providers to ensure timely delivery of lab supplies and stock checking.
• Track and manage personal protective equipment (PPE) inventory, perform regular checks, and replenish stock as needed.
• Maintain overall cleanliness and organization of the laboratories.
• Carry loads such as lab laundry and send for cleaning, drying and redistributing to storage cabinet.
• Perform ad-hoc duties as required to facilitate smooth and efficient operation of the lab.

Job Requirements:

• "N" Level/"O" Level/ITE/NITEC/Higher NITEC/Diploma.
• Minimum 2 years working experience in a BSL-2 laboratory setting.
• Experience in a high containment environment will be advantageous.
• Team player, proactive and possess good communication skills.
• Ability to work independently under minimal supervision.
• Wear PPE and don respirator to perform daily work.
• Knowledge of biohazard waste management and autoclaving procedures.
• Familiarity with research animal facility housekeeping.
• Attention to detail and strong organizational skills.
• Willing to learn and ability to follow strict safety protocols and guidelines

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.

Job Description:

We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher’s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.

The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology or related field
• Atleast 2 years of relevant experience in immunology or related field. No virology experience necessary.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Familiar with bioinformatics
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.

Job Description:

We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher’s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.

The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology or related field
• At least 4 years of relevant experience in immunology or related field. No virology experience necessary.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Familiar with bioinformatics
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

ROLE:

A*Star-IME is currently working on establishing a hybrid fabrication platform for 150mm and 200mm Silicon Carbide (SiC) power MOSFETs as a new pillar on Singapore"s Future of Microlectronics in wide-bandgap. The main objective of this SiC RnD program is to advance 200mm SiC technologies in various areas, such as epitaxy, device design, process integration & fabrication, and power module packaging. The ultimate aim is to drive disruptive innovations in power device research, specifically focusing on >1.7KV power MOSFETs. These innovations will have significant applications in enhancing automotive technologies, vehicle electrification, safety measures, sustainable energy grids, data centers, and industrial & aerospace automation. Key aspects for this role to be successful include the development and integration of several process modules, such as gate oxidation, implantation, implant activation, layout design verification, lithography, and ohmic contact formation. We are actively looking for individuals with extensive industry experience in device physics and process integration to join our team. The candidate will contribute to process integration, E-test and module process related data analysis, yield enhancement, and device physics.

RESPONSIBILITIES:

• Lead develop process technology for SiC power MOSFETs and ensure it meets the requirements for prototyping manufacturing

• Collaborate with advanced process module development team to establish a process flow for fabricating specific MOS devices

• Responsible to develop and improve test structures that enable fast and rigorous characterization of process

• Accountable to improve device performance and yield through the design, execution, and analysis of experiments for each specific device and product

• Work with cross-functional teams to minimize defects and address technical and yield concerns

• Drive CIP (Continuous improvement plans) to deliver integrated process modules and specific device per project goals

• Make decisions regarding the delivery of process, active and passive devices to multiple customers

REQUIREMENTS:

• MS/PhD Degree in Electrical Engineering or related field

• >3 years industrial experience for MOSFET process integration and device physics

• Proactive, self-motivated, and results-oriented professional with the ability to make efficient contributions to and lead technical discussions

• Extensive expertise in material and process integration

• Comprehensive understanding of semiconductor materials and the physics of MOSFET devices

• Strong communication skills to effectively communicate information about module integration for device fabrication and with customers

• Excellent analytical skills for interpreting process and device data, coupled with strong presentation abilities

ROLE:

A*Star-IME is currently working on establishing a hybrid fabrication platform for 150mm and 200mm Silicon Carbide (SiC) power MOSFETs as a new pillar on Singapore"s Future of Microlectronics in wide-bandgap. The main objective of this SiC RnD program is to advance 200mm SiC technologies in various areas, such as epitaxy, device design, process integration & fabrication, and power module packaging. The ultimate aim is to drive disruptive innovations in power device research, specifically focusing on >1.7KV power MOSFETs. These innovations will have significant applications in enhancing automotive technologies, vehicle electrification, safety measures, sustainable energy grids, data centers, and industrial & aerospace automation. Key aspects for this role to be successful include the development and integration of several process modules, such as gate oxidation, implantation, implant activation, layout design verification, lithography, and ohmic contact formation. We are actively looking for individuals with extensive industry experience in device physics and process integration to join our team. The candidate will contribute to process integration, E-test and module process related data analysis, yield enhancement, and device physics.

RESPONSIBILITIES:

• Lead develop process technology for SiC power MOSFETs and ensure it meets the requirements for prototyping manufacturing

• Collaborate with advanced process module development team to establish a process flow for fabricating specific MOS devices

• Responsible to develop and improve test structures that enable fast and rigorous characterization of process

• Accountable to improve device performance and yield through the design, execution, and analysis of experiments for each specific device and product

• Work with cross-functional teams to minimize defects and address technical and yield concerns

• Drive CIP (Continuous improvement plans) to deliver integrated process modules and specific device per project goals

• Make decisions regarding the delivery of process, active and passive devices to multiple customers

REQUIREMENTS:

• MS/PhD Degree in Electrical Engineering or related field

• >3 years industrial experience for MOSFET process integration and device physics

• Proactive, self-motivated, and results-oriented professional with the ability to make efficient contributions to and lead technical discussions

• Extensive expertise in material and process integration

• Comprehensive understanding of semiconductor materials and the physics of MOSFET devices

• Strong communication skills to effectively communicate information about module integration for device fabrication and with customers

• Excellent analytical skills for interpreting process and device data, coupled with strong presentation abilities

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking for a Principal Scientist to join us in our mission to be a leading centre of infectious diseases research. A*STAR IDL aims to develop a cohesive A*STAR response to drive and deliver translational infectious diseases research to better health and economic outcomes.

Job Description:

• Leads conceptual and technical integration of various research studies to provide leading edge solutions in antimicrobial resistance (AMR) research and development
• Conceptualize and create new technologies, patents and publications
• Review and manage operating budget of grants and team
• Establish collaborations, develop scientific proposals and ensure timely achievement of project milestones
• Manage a team and provide scientific and career mentorship to researchers and students

Job Requirements:

• PhD in Biomedical Sciences, Life Sciences, Microbiology, Molecular Biology, Infectious Diseases, Immunology or related field as above
• 4 years of post-PhD relevant experience
• Strong background in Microbiology, Immunology, Molecular Biology, Biochemistry, Genetics and Genomics
• Strong publication record
• Highly motivated and ability to develop strong research ideas to secure grant and funding
• Strong analytical, technical and problem-solving skills
• Team player with good interpersonal skills
• Good spoken and written communication skills

Job Description:

Candidate will be part of Far-Backend Of Line (Far-BEOL) team of process module engineers, advancing specialty technologies at IME. His or her main roles and responsibilities include:

• Develop and support Chemical Mechanical Planarization (CMP) unit process capabilities for silicon photonics, flat optics, advanced packaging, MEMS, and wide bandgap semiconductor applications.
• Deliver innovations involving process methodologies, materials, or approach, and generate intellectual property related to various aspects of CMP.
• Participate as team member with process integration teams to actively support CMP process development, optimization and troubleshooting for various industry and grant projects.
• File patents/know-hows on new development activities.
• Publish research findings in prestigious journals and conferences.

Job Requirement:

• Masters with specialization in Electronics / Microelectronics / Materials Engineering / Chemical Engineering / Materials Science/ Chemistry / Physics or equivalent.
• Minimum 5 years of experience in CMP technologies, preferably in an industrial setting.
• Prior hands-on experience working on industry-scale 200 mm or 300 mm CMP equipment platforms (e.g., AMAT or Ebara platforms), with in-depth technical knowledge in process development, materials, and inline process control related to CMP.
• Knowledge of silicon photonics, advanced packaging, MEMS, or wide bandgap semiconductor technology platforms would be a plus, but not mandatory.
• Strong experimental design (DOE) and data analysis skills is preferred.
• Good interpersonal and strong demonstrated skills in collaborating with internal and external stakeholders.
• At least 2 years of demonstrated experience in managing projects of moderate complexity is preferred
• Good analytical skills and oral/written communication skills, with ability to deliver clear and concise messages to both internal and external stakeholders.
• Self-driven with strong interest in next-generation applications of CMP technologies and industry trends.