We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to study the metabolic regulation of immune cells during the NASH to NASH-HCC progression.

Metabolic regulation of immune dysfunction during the progression of NASH to NASH-HCC

Description:

The lack of effective treatments for non-alcoholic steatohepatitis (NASH) and NASH-associated hepatocellular carcinoma (NASH-HCC) underscores the need to understand the transition from NASH to NASH-HCC. Identifying why some NASH patients develop HCC while others do not is a significant challenge, with growing evidence indicating that immune dysregulation plays a crucial role in this progression. The interstitial space, where cells receive nutrients and signals, significantly impacts immune function, suggesting that understanding the liver"s metabolic environment could reveal how immune cells behave during NASH progression to HCC. By profiling interstitial fluid metabolism and single-cell transcriptomics, the team aims to understand the metabolic regulation of the immune landscape in NASH to NASH-HCC progression. Using a high-fat, high-fructose, and high-cholesterol dietary mouse model that mirrors human progression, the team will study the metabolic and immune changes leading to NASH-HCC. In addition, the team’s preliminary findings show immune alterations and reduced levels of the bile acid hyodeoxycholic acid (HDCA) during NASH-HCC transition. The identified candidate will also test the potential of HDCA in preventing NASH to HCC transition, and further explore HDCA"s effects on immune cells.

Job responsibilities:

• Conduct in vitro wet lab experiments (e.g. cell culture, molecular biology and assays, microscopy etc)
• Conduct in vivo animal experiments (e.g. diet/treatment regimes, body weight & composition analyses, metabolic phenotyping, blood sampling etc)
• Conduct end-point animal experiments (e.g. terminal blood collection, tissue collection and sample preparation, whole tissue/organ imaging, serum measurements etc)
• Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings
• Interact and collaborate with and assist other researchers and collaborators on related projects
• Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction
• Assist in the preparation of grant applications and grant process reports
• Present findings both orally and in written form via presentations and publication in peer-reviewed journal
• Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals
• Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

The CPPS group is seeking a highly motivated scientist or senior scientist to lead and conduct research in Industry 5.0 smart manufacturing solutions and integrating digital technologies with AI-enabled physical production systems that promote human-centricity, environmental sustainability, and value chain resilience in manufacturing. The ideal candidate should have a strong background in controls and/or automation. Knowledge of PLC programming would be a strong advantage.

The key roles & responsibilities include, but are not limited to the following:

• Research into novel adaptive and autonomous control algorithms for scalable self-learning, self-optimizing and self-recovery production systems
• Working with a team of scientists and engineers to design and implement integrated IIOT and AI-enabled production systems for smart manufacturing
• Formulate scientific research directions and innovative proposals to secure competitive funding
• Understand the autonomous manufacturing domain and provide innovative solutions to industry problems in this area
• Familiarity with industry communication protocols such as OPC-UA, MQTT, Profibus, and RS-232 is needed

Job Requirement:

• PhD degree in Computer Science / Engineering, Electrical Engineering, Mechanical Engineering, with emphasis on controls and/or automation.
• Fresh Graduates with strong fundamentals in controls and IIOT are welcome. (For Senior Scientist) 5 years’ experience in research and leadership of R&D projects in the relevant area of expertise.
• Good track record of scientific publications in top journals or conferences
• Excellent technical presentation and writing skills
• Ability to develop and program PLCs and other control systems, utilizing platforms like TwinCAT, EcoStruxure, Codesys and others is a strong advantage
• Can-do attitude and able to work with different needs of various stakeholders
• Proactive team player and technically motivated to solve problems innovatively

Key responsibilities:

* Technical Support:

• Work closely with research scientiest and engineers to support R&D projects in advanced manufacturing technologies.
• Identify and recommend appropriate characterization techniques, test standard and methodology for projects.
• Perform sample preparation, equipment operation, data collection and report for metallurgical analysis, materials characterization and measurement.
• Operate and maintain analytical and test equipment, such as cross-section polisher, optical microscope with image processing software, mechanical tester, profilometer and spectrometers.

* Lab Management and day-to-day operations

• Maintain lab equipment in good working condition, lab consumables are adequately stocked and well managed.
• Source and purchase new equipment, modules and accessories.
• Prepare and update lab safety document RA/SWP. Implement and maintain 5S in the lab.
• Provide training and advice for lab equipment users.

Requirements:

• Diploma in Materials, Chemistry, Mechanical Engineering, or equivalent.
• Good communication skills.
• Self-motivated with a positive work and learning attitude.
• Team player who thrives in a collaborative environment

RESPONSIBILITIES

• Provide administrative and marketing support to the Sales & Marketing Divisions
• Prepare quotations, follow up on sales orders and tender preparations
• Generate reports and maintenance of database
• Help to build and maintain good relationship with customers

REQUIREMENTS

• Diploma/Degree holders, preferably with the background of medical, scientific or equivalent
• Prior experience in the medical/scientific equipment, devices and consumables industry would be an added advantage
• Entry level candidates are welcome to apply
• Good communication skills
• Proficient in Microsoft Office
• Meticulous and organized
• Good attitude and willingness to learn
• Knowledge of SAP/SAGE will be an additional advantage
• Good team player

RESPONSIBILITIES

• Management of fast-paced and/or complex projects undertaken by ITS Science & Medical in Singapore or regional areas.
• Responsible for project management of infrastructure services supplied/offered by the Company that include, but not limited to hospital infrastructure, animal facilities, laboratory furniture, industrial, schools and other systems.
• Manage ACMV, HVAC system laboratory projects to completion in both Singapore and/or international standard, adhering to quality assurance policies and meeting performance standards
• Liaise with all stakeholders including facility management, architects, M&E consultants on engineering design and user specification, ensuring compliance
• Part-take in project tendering meetings and provide technical advice to tender team
• Prepare and manage project schedule and monitor project activities by project team to ensure compliance to activity execution timeline
• Provide technical support to Support sales team from time to time.
• Ensure Workplace Safety and Health is implemented at site.

REQUIREMENTS

• Diploma/Bachelor’s Degree in Mechanical Engineering or related Engineering disciplines.
• Experience in ACMV is preferred.
• Preferably with 3-5 years of relevant work experience handling construction projects (designing & management)
• Valid Class 3 driving license and personal vehicle will be an added advantage.
• Team player with a great can-do attitude.
• Outgoing personality.

BENEFITS

• Attractive remuneration package
• Career development opportunities

RESPONSIBILITIES

• Provide comprehensive range of technical after-sales service support, installation, commissioning and repair plus preventive maintenance plans for scientific and/or biopharmaceutical equipment;
• Provide technical consultation to customers; with a focus on the refrigeration system;
• Respond to customers’ requests by troubleshooting problems and taking corrective actions within targeted timeline;
• Prepare service reports.

REQUIREMENTS

• ITE/Higher NITEC/Diploma/Degree in Electronics, Electrical, Mechanical Engineering or equivalent
• Minimum 3 years of relevant technical work experience in service/ maintenance;
• Ideally process experience in similar industry (scientific/biopharmaceutical);
• Understanding of refrigeration system as focus;
• Excellent communication and interpersonal skills;
• Able to work independently and a team player;
• Self-motivated, results-oriented individual with good business acumen;
• Valid Class 3 driving license and personal vehicle will be an added advantage

BENEFITS

• Attractive remuneration package
• Career development opportunities
• Excellent technical exposure in the scientific/biopharmaceutical industry
• Fixed Monthly Transport Allowance

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 5 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 2 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description

We are seeking a highly motivated and skilled Development Engineer specializing in ROS 2 to join our dynamic team. The role focuses on developing robotic solutions using ROS 2 and Robotics Middleware Framework (RMF) to drive the adoption of cutting-edge robotics technologies in industrial applications. The ideal candidate will play a pivotal role in bridging research innovations with real-world deployment, contributing to the full software development lifecycle of robotics projects while ensuring seamless integration with industrial systems.

Roles and Responsibilities

1. Software Development:

· Develop, test, and maintain robotics software solutions using ROS 2 and RMF.

· Write clean, efficient, and modular code in C++ and Python.

2. System Integration:

· Design and implement systems for deploying robotic solutions in industrial settings.

· Integrate robotic hardware, sensors, and actuators with ROS 2-based software solutions.

3. Project Execution:

· Plan and execute technical projects, ensuring timely delivery of milestones.

· Collaborate with cross-functional teams to translate research outcomes into deployable solutions.

4. Software Development Lifecycle:

· Contribute to all phases of the software development lifecycle (SDLC), including requirement gathering, design, implementation, testing, and deployment.

· Use version control systems (e.g., Git) effectively to manage and track code changes.

5. Systems Engineering and Technical Planning:

· Conduct systems engineering activities such as requirement analysis, system design, and validation planning.

· Translating business requirements into system requirements and validation methodologies in project planning and proposals

· Create technical documentation, including design documents, user manuals, and test plans.

6. Continuous Improvement:

· Stay updated with advancements in ROS 2, RMF, and robotics technologies.

· Identify opportunities to enhance performance, reliability, and usability of solutions.

Job Requirements

· Qualification & field of study: Bachelor's degree or higher in Robotics, Computer Science, Electrical/Mechanical Engineering, or related fields.

· Min. years of experience: 5 years

· Proficiency in C++ and Python programming.

· Experience in developing robotics applications using ROS 2

· Familiarity with Git for version control and collaborative development.

· Knowledge of the Robotics Middleware Framework (RMF) and its ecosystem.

· Familiarity with the software development lifecycle and best practices in software engineering.

· Ability to execute technical project planning and manage deliverables.

· Experience in systems engineering, including system design, requirements definition, and testing methodologies.

· Strong problem-solving skills and a proactive mindset.

· Effective communication and teamwork abilities.

· Adaptability to dynamic project requirements and timelines.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Key Responsibilities:

• Provide scientific and technical expertise to lead a research team to develop capabilities in ingredient fermentation
• Develop mechanistic understanding of the microbiology of fermentation
• Develop research proposals and seek research fundings
• Disseminate research findings through conference presentations and journal publications
• Build and maintain strong relationships with local and international research network

Job Requirements:

• Possess a PhD degree in microbiology, fermentation or relevant disciplines
• Excellent knowledge and experience in microbiology and food fermentation
• At least 5 year of independent research experience and leading a research team
• Strong supervisory skills
• Strong track record for securing research funding
• Excellent publication track record
• Excellent communication and interpersonal skills, with the ability to effectively engage with diverse stakeholders at all levels
• Track record of strategic thinking capability with a outcomes-oriented mindset, able to translate vision into actionable plans and driving their execution

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 2 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 5 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description

We are seeking an experienced and innovative Senior Scientist to lead advanced robotics research and development efforts in the areas of robotic path planning, simulator design, and AI-based solutions. This role involves working with ROS 2, Robotics Middleware Framework (RMF), and other state-of-the-art technologies to develop and deploy scalable robotic systems for industrial applications. The ideal candidate will combine a strong research background with hands-on development skills to advance the field of robotics and facilitate the translation of innovative solutions into real-world deployments.

Roles and Responsibilities

1. Research and Development:

• Lead the design and development of path planning algorithms for autonomous robots, including multi-robot coordination and dynamic environments.
• Conduct research on robot simulation tools to create realistic and scalable testing environments.
• Develop and implement AI/ML-based solutions for robot perception, decision-making, and task optimization.

2. Software Development and Integration:

• Architect and develop robust software using ROS 2 and RMF, focusing on scalability and interoperability.
• Develop, test, and maintain robotics software solutions using ROS 2 and RMF.
• Write clean, efficient, and modular code in C++ and Python.

3. Technical Leadership:

• Drive innovation by identifying and pursuing new research directions in robotics and AI.
• Collaborate with cross-functional teams to align research goals with industrial deployment needs.

4. Project Management:

• Lead the technical execution of robotics R&D projects, ensuring timely delivery of milestones.
• Plan, execute, and manage research projects, including proposal writing and securing funding.
• Develop technical documentation, research papers, and presentations for both internal and external stakeholders.

5. Knowledge Sharing and Collaboration:

• Publish findings in leading journals and conferences to contribute to the global robotics and research community.

Job Requirements

· Qualification & field of study: PhD degree in Robotics Engineering, Software Engineering, Computer Engineering, Electrical Engineering or Computer Science

· Min. years of experience: 3-5 years

· Proficiency in C++ and Python, with strong experience in ROS 2 and RMF development.

· Experience in designing and using robotic simulators (e.g., Gazebo, Unreal Engine, Nvidia Omniverse or custom solutions).

· Advanced knowledge of AI/ML frameworks (e.g., TensorFlow, PyTorch) and their application in robotics.

· Familiarity with robotic systems engineering, middleware frameworks, and sensor fusion techniques.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub).

The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 3+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub). The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 5+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• At least a minimum of 5 years of relevant experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to identify and validate candidates that address the body’s adaptive responses to weight loss.

TaRgeted Analysis of Novel Secreted Factors for Obesity Reduction and Metabolic Health (TRANSFORM)

Description:

Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g. mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies and therapeutic strategies.

Job responsibilities:

● Conduct in vitro wet lab experiments for identified candidates (e.g. cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy etc)

● Conduct in vivo screening experiments for prioritized candidates (e.g. in preclinical models of obesity)

● Conduct end-point and mechanistic experiments (e.g. target tissue and blood collection, sample preparation etc)

● Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings

● Interact and collaborate with and assist other researchers and collaborators on related projects

● Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction

● Assist in the preparation of grant applications and grant process reports

● Present findings both orally and in written form via presentations and publication in peer-reviewed journal

● Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals

● Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Key responsibilities:

* Technical Support:

• Work closely with research scientiest and engineers to support R&D projects in advanced manufacturing technologies.
• Identify and recommend appropriate characterization techniques, test standard and methodology for projects.
• Perform sample preparation, equipment operation, data collection and report for metallurgical analysis, materials characterization and measurement.
• Operate and maintain analytical and test equipment, such as cross-section polisher, optical microscope with image processing software, mechanical tester, profilometer and spectrometers.

* Lab Management and day-to-day operations

• Maintain lab equipment in good working condition, lab consumables are adequately stocked and well managed.
• Source and purchase new equipment, modules and accessories.
• Prepare and update lab safety document RA/SWP. Implement and maintain 5S in the lab.
• Provide training and advice for lab equipment users.

Requirements:

• Diploma in Materials, Chemistry, Mechanical Engineering, or equivalent.
• Good communication skills.
• Self-motivated with a positive work and learning attitude.
• Team player who thrives in a collaborative environment

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

The CPPS group is seeking a highly motivated scientist or senior scientist to lead and conduct research in Industry 5.0 smart manufacturing solutions and integrating digital technologies with AI-enabled physical production systems that promote human-centricity, environmental sustainability, and value chain resilience in manufacturing. The ideal candidate should have a strong background in controls and/or automation. Knowledge of PLC programming would be a strong advantage.

The key roles & responsibilities include, but are not limited to the following:

• Research into novel adaptive and autonomous control algorithms for scalable self-learning, self-optimizing and self-recovery production systems
• Working with a team of scientists and engineers to design and implement integrated IIOT and AI-enabled production systems for smart manufacturing
• Formulate scientific research directions and innovative proposals to secure competitive funding
• Understand the autonomous manufacturing domain and provide innovative solutions to industry problems in this area
• Familiarity with industry communication protocols such as OPC-UA, MQTT, Profibus, and RS-232 is needed

Job Requirement:

• PhD degree in Computer Science / Engineering, Electrical Engineering, Mechanical Engineering, with emphasis on controls and/or automation.
• Fresh Graduates with strong fundamentals in controls and IIOT are welcome. (For Senior Scientist) 5 years’ experience in research and leadership of R&D projects in the relevant area of expertise.
• Good track record of scientific publications in top journals or conferences
• Excellent technical presentation and writing skills
• Ability to develop and program PLCs and other control systems, utilizing platforms like TwinCAT, EcoStruxure, Codesys and others is a strong advantage
• Can-do attitude and able to work with different needs of various stakeholders
• Proactive team player and technically motivated to solve problems innovatively

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in dermatology, immunology, molecular allergy and clinical immunology
• Experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Join the Institute of Microelectronics (IME) to be immersed in cutting-edge semiconductor research. As a research institute within the Agency for Science, Technology and Research (A*STAR), IME bridges the gap between academia and industry. Our mission is to accelerate innovation in advanced packaging, piezoMEMS, SiC, RF/mmWave GaN, and photonics & sensors, and to develop talent and inspire in Singapore.

We are looking for a passionate individual to join our Technology-Business Development department. You will be responsible for sales and marketing, account management and industry development. If you're excited about the future of microelectronics and wish to contribute to the development of Singapore's innovation engine for microelectronics, we want you on our team!

Job Responsibilities

• Perform market intelligence, develop and execute go-to-market plans for commercialization of IME's research capabilities.
• Lead industry and customer engagements, understand their needs and work with Technology Development teams to formulate value propositions.
• Structure, review and negotiate contracts with industry partners and customers.
• Develop industry network, manage accounts and build relationships to win and retain industry partners and customers.

Job Requirements:

• Degree in Science or Engineering.
• Ability to think on the feet
• Result-oriented, analytical, proactive, resourceful and team player
• Good communication, presentation and interpersonal skills
• Resilience and adaptability to work in a fast-paced and fast-changing environment
• Passion to develop Singapore's semiconductor industry