Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, and other new antibody engineering technologies that are under development.
Research Assistant - Protein Production unit
Job Scope:
· Tool generation – expression vector construction, expression, stable cell lines development
· Antibody generation – B cell cloning, antibody library
· Antibody screening – ELISA, FACS, cell-based functional assay, confocal microscopy etc.
· Lead optimization – expression vector construction, protein expression
· Protein Analysis – Biacore analysis, column chromatography analysis (IE, SE, RP etc.), SDS-PAGE, other physiochemical analysis
· Pharmacokinetics – sample measurement in in vitro and in vivo samples and PK simulation
· Protein production – Cell culture, E.coli culture, program and operate protein purification equipment using the AKTA platform, protein analysis with SDS-PAGE, Western, and HPLC blot
Requirements:
· Degree in Biomedical Science/Biotechnology/Molecular Biotechnology or a related field with at least 1-2 years of related working experience.
· Familiar with basic laboratory procedures. Experience in Molecular Biology, Protein Chemistry, Protein Purification techniques, Cell culture, Flow Cytometry, Confocal Microscopy and other relevant skills will be an added advantage.
· Fresh graduates are welcome to apply
Interested applicants are invited to email their detailed resume, qualifications, availability, current and expected salary to: [email protected]
For more information regarding our Company, you may refer to our website at:
http://chugai-pharmabody.com/
We regret that only short-listed candidates will be notified
