Research Fellow, Bioinformatics - National Precision Medicine program
Lee Kong Chian School of Medicine (LKCMedicine) established in September 2010 is a partnership between Imperial College London and Nanyang Technological University (NTU), Singapore. Consistently rated amongst the world's best universities, Imperial College London is a science-based institution with a reputation for excellence in teaching and research while NTU is the only Singapore university listed in the Top 10 of the Times Higher’s 200 Under 50 Rankings and is ranked the world’s No. 1 young university by QS in the last three consecutive years.
LKCMedicine operates from two campuses – Yunnan Campus at Nanyang Technological University and Novena Campus, which is located in the precinct of the future HealthCity. At LKCMedicine, we recognize that synergies is the key to maximize research output and we seek to promote synergies between researchers in LKCMedicine itself and local and/or overseas researchers. We strongly believe that building synergies and robust collaborations will be the key to maximizing research output in today’s competitive environment.
We are currently recruiting a Research Fellow, Bioinformatics to join Professor John Chambers’ group at LKCMedicine as part of the National Precision Medicine (NPM) program. NPM This ambitious national collaboration comprises researchers from across Singapore’s major Research Institutes. The potential candidate will be a part of the core NPM Data Science Team working on the large-scale genetic studies. The primary dataset will comprise a large-scale database consisting of comprehensive phenotypic characterization and whole genome sequencing of 100,000 Singaporeans participating in the PRECISE-SG100K population study. Our aim is to use these genomic data to transform understanding of health and disease in Asian populations, and to advance healthcare in Singapore.
The candidate should have excellent communication and problem-solving skills, and the ability to work independently as well as in collaboration with multi-disciplinary teams across different partner institutions.
Key responsibilities:
- Quality control of large-scale biological datasets
- Genetic studies of clinical and molecular phenotypes at a population scale.
- Evaluation and application of appropriate statistical techniques, as well as developing and implementing innovative computational tools for analysis of multi-omics data.
- Building databases and visualization tools.
- Development of robust pipelines for data integration and analysis.
- Contribute to publication efforts and presentation of research findings.
Preferred qualifications:
- Master’s (+3 years working experience) or PhD degree in bioinformatics or statistical genetics, computational biology, or related field.
- Experience working with large genomic datasets; a good understanding of genomic approaches (including but not limited to genome/phenome-wide association studies, burden tests, QTL studies, colocalization, fine-mapping) are essential.
- Strong skills in scientific programming (R, Python) in the UNIX/LINUX environment.
- Experience working in high performance computing cluster.
This opening will be based at LKCMedicine Novena Campus, Singapore. Salary will be commensurate with experience and qualifications.
Application Procedure:
Please apply with names of two referees. Only shortlisted candidates will be notified.
