Bioinformatics DevOps & Data Engineer – Hummingbird Bioscience
Full-time position – SG based location
ABOUT HUMMINGBIRD BIOSCIENCE
Hummingbird Bioscience is a precision biotherapeutics company discovering and developing transformative biologics for hard-to-treat diseases. To address key challenges with current antibody-drug conjugate (ADC) therapies, Hummingbird Bioscience is building a pipeline of next-generation ADCs using its proprietary antibody discovery and linker/payload platforms. The company has a pipeline of ADCs in preclinical development and other novel biologics including monoclonal antibodies, HMBD-001 (anti-HER3 mAb) and HMBD-002 (anti-VISTA mAb) in Phase I and a recently out-licensed ADC (HMBD-501) that will enter the clinic this year. The Hummingbird Bioscience approach combines computational and systems biology with wet lab drug discovery in a multi-disciplinary, collaborative environment spanning initial discovery through clinical development. The company harnesses this integrated approach across target identification and patient selection, enabling the team to increase the efficiency of translating novel scientific insights while reducing the inherent risk in drug discovery and development. At Hummingbird Bioscience, the commitment to rigorous science, teamwork, and intellectual integrity underpins our passion to accelerate the journey of new drugs from concept to clinic.
For more information, please visit www.hummingbirdbioscience.com, and follow Hummingbird Bioscience on LinkedIn, X (formerly Twitter), and YouTube.
ABOUT THE ROLE
The Bioinformatics team at Hummingbird Bioscience is expanding to meet the challenges in precision oncology. Our team delivers data-driven, actionable insights through the application of computational approaches to guide strategic decisions in clinical development that are already having a profound impact on the lives of patients.
We are looking for a talented and highly motivated Bioinformatics DevOps and Data engineer. The ideal candidate should possess a strong background in applying software principles and best practices when designing, developing, testing, and maintaining databases, pipelines, and applications. These contributions will play a crucial role in advancing the development of the next generation of cancer therapies.
KEY RESPONSIBILITIES
- Develop and maintain new and existing applications for science teams as required
- Design and maintain a centralized data hub of SQL/NoSQL databases of both publicly available and internally generated datasets
- Design and implement ETL processes for data extraction and transformation
- Develop workflows that integrate multiple data processing algorithms to generate summaries and reports
- Build containerized applications and tools (Docker/singularity)
- Provide platform and software support (clarifying and troubleshooting issues) on HPC and AWS for bioinformatics scientists
- Develop and improve the functionality of analytical dashboards
- Aggregate results from multiple analytical pipelines to generate comprehensive reports
- Write maintainable production-level code and testing changes to current application/database/workflow builds
- Review existing code base and deployment architecture and support adding functionalities to the pipeline
- Design of cloud environments for secure data storage and deployment of analytical pipelines
- Create documentation to ensure the proper establishment, description and continuity of processes
- As needed undertake data analyses for specific bioinformatics or projects
ESSENTIAL QUALIFICATIONS
- Bachelor/Master’s degree in computer science, software engineering, information systems, or equivalent experience in a related field
- Good knowledge of Python programming
- Proficient in developing and maintaining SQL/NoSQLdatabases
- Familiarity in developing workflow pipelines using technologies such as CWL or Nextflow
- Expertise in using Unix operating systems and HPC job schedulers (SLURM)
- Experience in full stack application development/deployment, and able to implement new features swiftly
- Demonstrated ability to containerize tools (docker/singularity)
- Strong communication skills, with a focus on documentation
- Ability to work independently and collaborate with other team members
- Excellent interpersonal skills with the ability to build strong relationships with stakeholders
- Familiarity with AWS cloud services and concepts
- Experience in front-end and back-end software development
DESIRABLE QUALIFICATIONS
- Familiarity with data cleaning, feature engineering and data analysis
- Experience of building and deploying applications in Biotechnology or Drug discovery or health care domains
- Familiarity with R/Shiny app development
- Familiarity with R and ggplot2 for data visualization
- Knowledge of additional database frameworks
- 1-3 years of relevant experience
- Desire and interest to mentor others to effectively support project tasks
- The ability to work on simultaneous projects, and to adapt to changing priorities with tight deadlines
OUR MISSION & VALUES
Our fast-growing biotechnology company is committed to discovering and developing important new drugs for cancer and autoimmune diseases, and living by our values: Excellence, Determination, Teamwork, Intellectual Integrity and Audacity.
JOIN US AT THE FRONTIER OF DRUG DISCOVERY AND DEVELOPMENT
We are looking for passionate and motivated individuals committed to solving important, complex problems. We are committed to the personal and professional development of our team and offer robust learning and development programs. Hummingbird Bioscience understands the need for flexibility for our team and offers a generous paid time off program with flexibility to support employees through different life stages. We invest in our team’s health by offering competitive benefits including health and dental insurance, and a comprehensive and holistic employee assistance program. We foster a more collaborative, productive, and sociable culture with on-site lunches and snacks. Finally, we believe in creating social impact beyond our business through corporate social responsibility initiatives.
Are you ready to join us on our mission to discover and develop important new drugs for cancer and autoimmune disease? Click on ‘Apply for this Job’ to submit your application.