Total 88 lab technician job vacancies in Others category in d18 tampines pasir ris

Auristone is an Asian-based epigenomic profiling company with data analytics capabilities that spun out from Genome Institute of Singapore (GIS) in 2021 with the vision to be the largest curator of Asian Epigenomic database to drive epigenomic discoveries. We are currently seeking a Laboratory Technologist to actively participate in driving the service offerings in the company. This role will also require the candidate to support the end-to-end workflow for our flagship products EPI-CALL™ and Signomax™.

Job Responsibilities:

1. Handle the receiving and testing of samples/specimens received.

2. Perform Quality Checks (QC) where required.

3. Record all experimental findings in accordance with company regulations.

4. Communicates experimental results, and issues faced, to reporting officer.

5. Support lab inventory and procurement of reagents, consumables, and equipment, when required.

6. Perform routine equipment maintenance and calibration as per SOP requirement, when required.

7. Communicate and cooperate with team members and conform to all rules and regulatory requirements of lab facilities.

8. Prepare documentation, reports, and present experimental findings and data.

9. Any other ad-hoc activities required by the role.

Skills/Qualifications

1. Highly organized, able to multi-task, and ability to pay close attention to details. Rigorous execution of experimental protocols is critical.

2. Ability to work in a collaborative manner with reporting officer, to achieve long- and short-term goals is required.

3. Ability to perform basic data analysis and interpretation and perform troubleshooting experiments when required.

Education/Experience Requirements

1. Qualification: Bachelor of Science in Molecular Biology, Biomedical Sciences, Biomedical Engineering or related field.

2. Work experience: 1-3 years.

3. Technical skills:

a. Proficiency in DNA/RNA extraction from FFPE samples is preferred, but not required

b. Proficiency in Next Generation Sequencing (NGS) workflow and sample library preparation is preferred, but not required.

c. Basic knowledge in molecular biology techniques

d. Proficiency in MS Excel, including basic functions and formulas.

The “Cellular Basis of Neural Diseases” laboratory in the Institute of Molecular and Cell Biology, A*STAR invites applications for a position as Senior Scientist I (Postdoctoral Research Fellow) in Cellular and Metabolic Therapies for Neurological Diseases.

The goal of the program is to derive clinically relevant neural cell types from induced pluripotent stem cells for development of novel therapies. This will be achieved through enhanced biological understanding of the disease progression and identification of new disease targets.

Interested candidates should have a PhD degree in Biomedical Sciences, Neuroscience, Stem Cells and Regenerative Biology or a relevant field. The ideal candidate should possess the following characteristics:

• Passionate and committed to advance the frontiers of Stem Cell/Neuroscience research
• Excellent communication skills (both written and oral)
• A team player who can perform well with colleagues as well as independently
• Proven track record of scientific research evidenced by strong publication record
• Experience with neural organoid cultures, as well as single cell RNA-seq analyses would be highly desirable
• Meticulous and organized

Role and Responsibilities:

Prepare resources, and chemical solutions, assemble apparatus, and deliver equipment to labs as required.

Assist teachers and students with technical advice and resources during lessons.

Inventory management of all science equipment, apparatus, and consumables.

Source and recommend equipment to replace damaged ones.

Be responsible for clearing, storing, and maintaining equipment and fume hood units.

Clear, tidy up, and put away glassware and equipment in labs daily.

Fix broken equipment or seek assistance for repair/replacement.

Support other departments in administrative jobs during school holidays.

Requirements:

Qualification- A degree or diploma in a relevant scientific field (e.g., Chemistry, Biology, Physics) or equivalent practical experience.

Experience:- Previous experience working as a laboratory technician in a high school or educational setting is preferred.

Experience with high school-level science experiments, equipment, and safety protocols.Skills and Abilities:- Strong understanding of laboratory safety practices and procedures.

Ability to troubleshoot, repair, and maintain science laboratory equipment.

Excellent organizational skills, attention to detail, and multitasking skills.

Ability to work independently and as part of a team.

Good communication skills to interact with staff, students, and parents as needed.

Proficiency in English (both written and spoken) is required, as this is the language of instruction.

Job Description and Requirements

A postdoctoral senior/ research fellow (scientist) position is available in Tan Yee Joo’s lab to work on hepatitis B virus. Candidate is required to work closely with fellow lab members and collaborators in a joint grant.

Requirements:

• PhD in Biomedical Science or related fields
• Highly experienced in common biochemical techniques including PCR, real-time PCR, Western blot and immunofluorescence assays
• Highly experienced in mammalian cell culture methodologies including gene knockout/knockdown, transient and stable transfections
• Experienced in virology is preferred
• Experienced in performing pathway analysis of datasets from proteomics and transcriptomics experiments is preferred
• Experienced in chromatin immunoprecipitation assay is preferred
• Have a strong publication record in peer-reviewed journals
• Be able to work in a team and conduct independent research with excellent analytical, technical and problem-solving skills

Job Description and Requirements

A postdoctoral senior/ research fellow (scientist) position is available in Tan Yee Joo’s lab to work on hepatitis B virus. Candidate is required to work closely with fellow lab members and collaborators in a joint grant.

Requirements:

• PhD in Biomedical Science or related fields
• Highly experienced in common biochemical techniques including PCR, real-time PCR, Western blot and immunofluorescence assays
• Highly experienced in mammalian cell culture methodologies including gene knockout/knockdown, transient and stable transfections
• Experienced in virology is preferred
• Experienced in performing pathway analysis of datasets from proteomics and transcriptomics experiments is preferred
• Experienced in chromatin immunoprecipitation assay is preferred
• Have a strong publication record in peer-reviewed journals
• Be able to work in a team and conduct independent research with excellent analytical, technical and problem-solving skills

About Us:

At BioDefense, we aim to enhance the quality and safety of perishable foods with our cutting edge microbial safety solutions. We are looking for a passionate and motivated Lab Assistant to join our team. If you're eager to kickstart your career in a dynamic laboratory environment, we want to hear from you!

Job Summary:

As a Lab Assisstant, you will play a crucial role in the manufacturing and quality control processes of our product . You will assist in the preparation, testing, packaging and ensuring that our products meet the highest standards of quality and safety. This position is perfect for someone looking to gain hands-on experience in a laboratory setting while contributing to cutting-edge food preservation solutions.

Key Responsibilities:

- Assist in the preparation of our product according to established protocols.

- Conduct routine tests and analyses on raw materials and finished products to ensure quality standards are met.

- Maintain accurate records of production activities, including batch logs, test results, and inventory levels.

- Support the cleaning and maintenance of laboratory equipment and workspaces to ensure a safe and organized environment.

- Collaborate with senior lab staff to troubleshoot and resolve production issues as they arise.

- Follow all safety guidelines and standard operating procedures (SOPs) in the laboratory.

- Participate in team meetings and contribute to continuous improvement initiatives in the production process.

Qualifications:

- Degree in Food Science, Biology, Chemistry, or a related field (or relevant coursework).

- Previous laboratory experience (internships, coursework, or volunteer work) is a plus but not required.

- Strong attention to detail and ability to follow protocols precisely.

- Good communication and teamwork skills.

- Willingness to learn and adapt to new techniques and procedures.

- Basic computer skills for data entry and record-keeping.

How to Apply:

If you are excited about starting your career in laboratory production and making a difference in food safety, please submit your resume and interest in the position to [email protected].

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in dermatology, immunology, molecular allergy and clinical immunology
• Experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with experience in dermatology, immunology, molecular allergy and clinical immunology
• At least 2 years experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Technical maintenance skills:
· Repair cell phones, tablets and other electronic devices, including screen replacements, battery replacements and component-level repairs.

· Proficiency in the use of specialized tools and equipment to disassemble, reassemble and test mobile equipment.

quality assurance:

· Follow standardized repair procedures and quality control measures to ensure repairs comply with company standards and industry specifications.

· Conduct thorough testing and inspection of repaired equipment to verify functionality and identify any remaining issues.

· Accurately and comprehensively document maintenance activities, including parts used, repairs performed and test results.

Recommend suitable mobile phone accessories according to customer needs.

58 RECRUITMENT PTE. LTD

12C5922

99668864

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking a Laboratory Officer/ Technician (BSL-3 operations) to join us.

The Laboratory Officer/ Technician will engage in day-to-day operations, housekeeping, maintenance of the high containment (BSL-3) and BSL-2 enhanced laboratories. This role will involve but is not limited to the following:

Job Responsibilities:

• Perform lab biohazard waste collection, sort, autoclave, and safe disposal.
• Liaise with biohazard waste contractor for scheduled disposal.
• Manage laboratory supplies, chemical and equipment inventory.
• Assist in coordination of the lab maintenance, calibration, repair of faulty and recertification of laboratory equipment.
• Coordinate with vendors and service providers to ensure timely delivery of lab supplies and stock checking.
• Track and manage personal protective equipment (PPE) inventory, perform regular checks, and replenish stock as needed.
• Maintain overall cleanliness and organization of the laboratories.
• Able to carry loads such as lab laundry and send for cleaning, drying and redistributing to storage cabinet.
• Perform ad-hoc duties as required to facilitate smooth and efficient operation of the lab.

Job Requirements:

• "N" Level/"O" Level/ITE/NITEC/Higher NITEC/Diploma.
• Minimum 2 years working experience in a BSL-2 laboratory setting.
• Experience in a high containment environment will be advantageous.
• Team player, proactive and possess good communication skills.
• Ability to work independently under minimal supervision.
• Able to wear PPE and don respirator to perform daily work.
• Knowledge of biohazard waste management and autoclaving procedures.
• Familiarity with research animal facility housekeeping.
• Attention to detail and strong organizational skills.
• Willing to learn and ability to follow strict safety protocols and guidelines

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

• can work on publick holidays
• can work on shifts/change of shifts
• can work and stand for long hours
• at least 10 years experiences
• have relavant certificates
• 
  
• Provide overall supervision of production activities.
• Plan, organize and lead a team of production workers to achieve production target and output, cycle time, and yield.
• Improvement in maintaining product quality and productivity. Provide a guideline to check on processes thereby assuring that work is done by the operators.
• Monitor the daily efficiency status of the line.
• Ensure good housekeeping and safety at the workplace.
• Oversee hiring and training of food production personnel
• Perform other duties as assigned.

Host Pathogen Interactions in A*STAR Infectious Diseases Labs (A*STAR ID Labs) is seeking a Postdoctoral Researcher to join the lab.

We are seeking a talented and collaborative post-doctoral researcher to work in the broad scope of host-pathogen interactions and infectious diseases. The lab has various funded projects on the comparison of host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric and multiOmic approach. Other projects include immune response evaluation of vaccine adjuvant candidates, development of cell-based reporter systems of viral infections to facilitate and accelerate antiviral studies, as well as development of novel vaccine strategies.

The candidate will be expected to work on funded projects as well as develop novel research projects in the scope of the lab research interests to be able to apply to the various early career development schemes both at an internal and external national level. Virus studied in the lab are positive sense RNA viruses as well as some negative sense RNA viruses. Other common techniques and tools in the lab include protein-protein/RNA interactions, microscopy, functional genomics, viral reverse genetics, CRISPR Cas9 gene editing. Animals models available in the lab include mice and zebrafish.

Throughout the project, close collaborative work within A*STAR ID Labs as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology, Virology or related field
• At least 2 to 3 years of relevant experience (immunology or related field) is a plus.
• No virology experience necessary. Prior bioinformatic experience is a plus.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Technician Responsibilities:

• Diagnose, troubleshoot and repair mobile devices;

• Quality control and testing of repaired devices to ensure full functionality. Resolve/manage customer inquiries;

• Able to interact positively with customers at the storefront and over the phone;

• Ability to multi-task between repairs and customer service;

• Other related duties as required;

• Maintain and use repair tools and equipment. Including software and in-store POS system to track repair tickets and inventory;

• Strategically plan the order of operations to ensure a successful repair;

• Provide estimates and quotes;

• Glass only replacement on Samsung and iPads;

• Microscopic Board work; component replacement Hand-solder SMT components,

• remove and replace thru-hole comp without board damage,

• solder wires and cables,

• Diagnosis, troubleshoot and repair mobile devices;

• identify assembly and documents issues;

• Repair logic board issues from water damage.

Requirements:

• Excellent knowledge of customer service best practice with previous experience;

• Ability to repair a variety of mobile devices (i.e., iPhone, Samsung, LG, Motorola, Sony, Huawei and OnePlus phone, and iPads.);

• Ability to communicate effectively with a wide variety of people in a professional manner, face to face, on the telephone and in writing;

• Knowledge of mobile devices including manufacturers, operating systems, and network service providers;

• Willing to work flexibly and with enthusiasm;

• Excellent organizational skills;

• Good attention to detail and ability to show initiative;

• Ability to demonstrate practical troubleshooting and problem analysis techniques;

• Ability to plan and prioritize your workload without supervision

Technician Responsibilities:

• Diagnose, troubleshoot and repair mobile devices;

• Quality control and testing of repaired devices to ensure full functionality. Resolve/manage customer inquiries;

• Able to interact positively with customers at the storefront and over the phone;

• Ability to multi-task between repairs and customer service;

• Other related duties as required;

• Maintain and use repair tools and equipment. Including software and in-store POS system to track repair tickets and inventory;

• Strategically plan the order of operations to ensure a successful repair;

• Provide estimates and quotes;

• Glass only replacement on Samsung and iPads;

• Microscopic Board work; component replacement Hand-solder SMT components,

• remove and replace thru-hole comp without board damage,

• solder wires and cables,

• Diagnosis, troubleshoot and repair mobile devices;

• identify assembly and documents issues;

• Repair logic board issues from water damage.

Requirements:

• Excellent knowledge of customer service best practice with previous experience;

• Ability to repair a variety of mobile devices (i.e., iPhone, Samsung, LG, Motorola, Sony, Huawei and OnePlus phone, and iPads.);

• Ability to communicate effectively with a wide variety of people in a professional manner, face to face, on the telephone and in writing;

• Knowledge of mobile devices including manufacturers, operating systems, and network service providers;

• Willing to work flexibly and with enthusiasm;

• Excellent organizational skills;

• Good attention to detail and ability to show initiative;

• Ability to demonstrate practical troubleshooting and problem analysis techniques;

• Ability to plan and prioritize your workload without supervision

Duties and Responsibilities - Process Integration

• Plan the integration flow with device designers
• Draft the runsheet by translating the flow into process steps and capturing necessary shortloops
• Perform the DoE with process module teams
• Track the lot and report the progress
• Identify failure modes/root causes and address the problems by proposing changes
• Must be good at documentation and written communication

Job Requirements

• Bachelor's degree in Microelectronics, Electrical, Mechanical, or Chemical Engineering.
• A basic understanding of the semiconductor processes is preferred.
• 3-5 years of hands-on experience in semiconductor processes (Diffusion, Wet Clean, CMP, ECP, Litho, Etch, CVD, PVD, etc.) will add advantages.
• Must be a team worker with the project stakeholders (device design, process module, and equipment/facility).

JOB DESCRIPTION

• Monitor, assist and perform on-going operations at tankfarm and jetty area
• Assist to line-up the pipeline system, inspect pipes, pumps, valves and tanks to ensure discharging, loading, processing and tank-to-tank transfers are performed in accordance to the company's work procedures
• Carry out first-line maintenance, i.e. replacing blinds, greasing of valves and oiling of operational equpment
• Assist in daily operations, including proper housekeeping at site

REQUIREMENTS

• Fresh graduates with Diploma, Higher/Nitec in engineering disciplines are welcome
• Willing to perform outdoor fieldwork
• Willing to perform 12 hours rotating shift (alternate weekend not working)
• Travel to offshore island (near Jurong Island), with monthly Offshore and Transport Allowance
• Class 4 driving license added advantage
• On Job Training provided

On behalf of CTS Asia Pacific, we are looking for a PLC/Robotics Engineer!

While this role is customer-facing, in addition to the customer, work tightly together with the Project Manager, and other project team members as required to support each other in our close-knit team.

The preferred educational background in one of more of the following Software Engineering, Mechanical Engineering, or Electronic/Electrical Engineering from a local institution in Singapore. We welcome ITE graduates, but expect you to show 3-5 years relevant experience. For Diploma holders, 2-3 years; and for Degree holders, 1-2 years experience is expected. Training will be provided!

What are you expected to do?
- Project planning of automation solutions for industrial manufacturing plants
- Simulation of the process plant
- Software creation (e.g. robots, safety controls or HMI)
- Integrating drives and robots into the machine
- Commissioning of the machine with the software created for process testing in-house, and start-up support for the customer

What should you bring with you for this application?
- Good to have: Relevant experience and knowledge in Siemens PLC.
- Points of contact in the programming of controls (e.g. Simatic S7, TIA, PCS7, B&R, Beckhoff etc.)
- Creating user interfaces and/or drive technology is desirable but not a must
- Enjoy holistic project processing and an agile way of working
- Interest in technical challenges and robots

Do note that we are on the lookout for key members who can work independently and responsibly in a local team with collaboration from HQ in Germany.

It should also be exciting for you to know that training opportunities are ample in Singapore, and exchange abroad are available; in the future, projects scope will expand regionally too.

Responsibilities

• Receive biological samples from customers for NGS Sequencing
• Prepare sequencing libraries, perform quality assessment and perform sequencing runs
• Analyze sequencing data and report results to customers in a timely manner
• Assist in ensuring proper documentation of all processes including the monthly report of sequencing services conducted
• Assist in troubleshooting for customers
• Interact with bioinformaticians and evaluate bioinformatics output
• Maintain lab equipment & documentation in accordance with quality requirements of ISO and CAP accreditation standards
• Supervise and train junior staff
• Other ad-hoc projects as required by the superiors

Requirements

• Degree in Genetics, Biology or related life sciences major (Diploma with relevant major may apply too)
• 0-3 years lab work experience
• Hands-on NGS experience is highly desirable
• Strong molecular biology background
• Familiar with real-time PCR, bioanalyzer, sequencing assays
• Familiar with bioinformatics software and methodologies is a plus
• Good analytical skills and detail-oriented
• A committed team player who is enthusiastic and willing to learn
• Comfortable with flexible working hours and shift work

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Postdoctoral Scientist position

A postdoctoral scientist position is available immediately in the laboratory of Dr. Leslie Beh at IMCB.

The Beh lab seeks to develop cutting-edge CRISPR-Cas technologies to uncover the biological functions of RNA modifications. Dysregulation of these modifications has been linked to cancer, neurological disorders, and metabolic disease. We will determine the mechanisms by which RNA modifications and CRISPR-Cas systems operate by drawing upon diverse techniques, including protein engineering, biochemical reconstitution, genomics, and cell-based experiments. Successful applicants can expect close mentorship in a collaborative environment, with an emphasis on developing scientific knowledge and individual career goals. More information about can be found at (https://www.behlab.org/).

Requirements:

• Ph.D. in Life Sciences / Biomedical Sciences
• Experience in biochemistry and/or structural biology, particularly in protein-RNA or protein-DNA interactions.
• in vitro reconstitution of enzymatic activity using cell extracts or purified proteins
• Recombinant protein purification from bacterial and insect cells
• Genuine interest in pursuing a research-based career.
• Strong work ethic, with excellent organizational and communication skills

Preferred experience:

• Mammalian cell culture
• NGS library generation and data analysis
• Prior roles in lab management

Postdoctoral Scientist position

A postdoctoral scientist position is available immediately in the laboratory of Dr. Leslie Beh at IMCB.

The Beh lab seeks to develop cutting-edge CRISPR-Cas technologies to uncover the biological functions of RNA modifications. Dysregulation of these modifications has been linked to cancer, neurological disorders, and metabolic disease. We will determine the mechanisms by which RNA modifications and CRISPR-Cas systems operate by drawing upon diverse techniques, including protein engineering, biochemical reconstitution, genomics, and cell-based experiments. Successful applicants can expect close mentorship in a collaborative environment, with an emphasis on developing scientific knowledge and individual career goals. More information about can be found at (https://www.behlab.org/).

Requirements:

• Ph.D. in Life Sciences / Biomedical Sciences
• Experience in biochemistry and/or structural biology, particularly in protein-RNA or protein-DNA interactions.
• in vitro reconstitution of enzymatic activity using cell extracts or purified proteins
• Recombinant protein purification from bacterial and insect cells
• Genuine interest in pursuing a research-based career.
• Strong work ethic, with excellent organizational and communication skills

Preferred experience:

• Mammalian cell culture
• NGS library generation and data analysis
• Prior roles in lab management

Responsibilities

• Receive biological samples from customers for NGS Sequencing
• Prepare sequencing libraries, perform quality assessment and perform sequencing runs
• Analyze sequencing data and report results to customers in a timely manner
• Assist in ensuring proper documentation of all processes including the monthly report of sequencing services conducted
• Assist in troubleshooting for customers
• Interact with bioinformaticians and evaluate bioinformatics output
• Maintain lab equipment & documentation in accordance with quality requirements of ISO and CAP accreditation standards
• Supervise and train junior staff
• Other ad-hoc projects as required by the superiors

Requirements

• Degree in Genetics, Biology or related life sciences major (Diploma with relevant major may apply too)
• 0-3 years lab work experience
• Hands-on NGS experience is highly desirable
• Strong molecular biology background
• Familiar with real-time PCR, bioanalyzer, sequencing assays
• Familiar with bioinformatics software and methodologies is a plus
• Good analytical skills and detail-oriented
• A committed team player who is enthusiastic and willing to learn
• Comfortable with flexible working hours and shift work