Laboratory of Regulatory Genomics is a cutting-edge research facility that focuses on the field of spatial and single cell genomics. We are dedicated to developing tools and investigating the complex biology of individual cells to gain a deeper understanding of cellular processes and translate them into tangible therapeutics. Our research encompasses a wide range of applications, including cancer biology, drug development and drug delivery. Our team is composed of highly skilled and motivated researchers who work collaboratively to push the boundaries of single cell genomics and contribute to the advancement of biomedical research.

We are seeking a talented Postdoctoral Researcher to join our team and work on Spatial and Single Cell Genomics projects. The successful candidate will have a PhD in molecular biology, genomics, or a related field, and will be responsible for designing, developing, and conducting experiments involving the integration of spatial transcriptomics and single cell genomics related to drug discovery, development, and delivery.

Key Responsibilities:

• Design and execute experiments to investigate gene expression in single cells and spatially resolved tissue samples
• Analyze data from transcriptomic and genomic assays including single cell RNAseq, spatial transcriptomics, and other sequencing technologies
• Develop and optimize experimental protocols for large scale single cell genomics and/or spatial transcriptomics
• Maintain detailed experimental records and contribute to scientific reports and publications
• Collaborate with other members of the team to develop and implement research strategies

Qualifications:

• A PhD in molecular biology, genomics, or a related field
• Proven experience in single cell genomics and/or spatial transcriptomics is a plus
• Strong experience with molecular biology techniques, including sample preparation, RNA isolation, and sequencing library preparation
• Proficient in data analysis tools such as R, Python
• Experience with microscopy, image analysis, and statistical analysis would be advantageous
• Ability to work independently and collaboratively with other team members
• Excellent organizational skills and attention to detail

This is an excellent opportunity to join a dynamic and growing research team, with excellent prospects for career development. The position is offered on a fixed-term contract for a period of [Insert duration] months. If you are a highly motivated and enthusiastic individual with a passion for molecular biology and genomics, we encourage you to apply.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A Scientist position is available at the Hair & Pigmentation Development Laboratory within A*STAR Skin Research Labs, a partner in the Skin Research Institute of Singapore. This candidate will become part of our research group to elucidate mechanisms regulating hair morphogenesis, growth and regeneration. This project will take up 100% of his/her time. The research fellow will lead the project and oversee a team composed of a research officer and a student.

Job Responsibilities:

• Cell culture of primary skin cells
• 2D and 3D co-culture models of hair follicle cell
• Prospective isolation of human and mouse hair follicle cells
• Whole and spatial transcriptome analysis
• Hair induction mouse models

Job Requirements:

• Degree in Biology, Bioengineering, Life Sciences or equivalent
• Advanced cell culture and molecular techniques
• Experienced with 2D and 3D skin organotypic assays
• Experienced with mouse in-vivo models
• Experienced with RNA, single-cell and spatial transcriptomics analyses
• Excellent communication (verbal and written) and presentation skills
• Highly motivated, passionate about science, committed to laboratory work and able to work flexible hours, as required by experimental planning

Job Description:

• Engage with companies and agencies to understand their businesses, product/service offerings & technology needs.
• Foster R&D collaboration between companies/agencies with researchers/research units in A*STAR SRTT, to drive impactful outcomes.
• Proliferate IP portfolio of A*STAR SRTT through technology productization, licensing or formation of new spin off.
• Work closely with industries and agencies to market the portfolio and research capabilities through collaboration and facilitate the technology transfer as needed.
• Work closely with scientists and principal investigators in determining the scope of projects, costing estimation, agreement drafting, and negotiation with industries and agencies.
• Provide management reporting support, market intelligence and facts gathering to facilitate decision-making and occasionally convinces others where strong interests exists to adopt new concepts and approaches.
• Analyse problems and ensure compliance to A*STAR practices and policies.
• Drive or support the development and execution of industry strategy for key R&D programmes under SRTT.
• Takes ownership and responsibility for team's action and decision.

Requirements:

• Master in Physical Sciences or equivalent.
• 5 years of industry/agency experience, with 3-5 years in a business development and/or technical strategic planning and execution role.
• Candidates with experience and knowledge in advanced scientific concepts and cutting-edge technologies, preferably in advanced computing, high performance computing, quantum , semicon/electronics, will have an advantage.
• Experience in project management in an R&D, Technology and/or Operations environment, interfacing with private and public sector agencies would be a plus.
• Excellent oral and written communication skills.
• Pro-active, quality conscious, and results-oriented.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Strategic Innovation role is to support GIS T-BD office to develop, manage and track each innovation project in GIS within the FoS funnel.

He/She is to take the lead to drive translation outcome using the FoS engine as a mechanism such as calling/scouting/fishing for new innovation ideas, developing innovation projects, and validating/supporting the projects leaders to achieve funding and eventual spin-off. He/She will also constantly innovate and improve the FoS engine by working closely with GIS management and I&E, hence allowing the GIS to establish good and successful spin-offs.

1. Calling/scouting/fishing for new innovation ideas within GIS. Discussing with PIs, GIS Tech Biz Research Partnership team, Post-docs, to identify new innovation ideas to develop into innovation projects.

a) Attend GIS scientific event (ie. GIS weekly) to scout potential innovation ideas with commercial value.

b) Attend GIS Tech Biz TD showcase/review to scout potential innovation ideas from the TDs.

2. Work with Innovation Project Leaders to qualify/validate problem statement.

3. Work with PIs/Innovation Project Leaders to provide commercial assessment/evaluation (ie. Market assessment, validation with industry players) to the Innovation Projects.

4. Track, manage and report out progress of each innovation project.

5. Main point of contact for GIS? FoS.

6. Manage and oversees the community of EIR (including Innovation Project Leaders, GIS Innovation Fellow, Aspired Entrepreneur and Spun-off Alumni).

7. Any other duties assigned by supervisor.

Job requirements

1. Degree in Business Administration or equivalent, or Degree in scientific discipline related to GIS core businesses, e.g. Bioinformatic, or biomedical engineering, or biology, or chemistry, or equivalent.
2. Must possess an entrepreneurial spirit, must be innovative and drive to create, modify and build new frameworks to achieve objectives.
3. 5 years of industry experience in R&D, Business Development in medical devices and life sciences preferred or related industries.
4. Prior experiences leading innovation projects are preferred.
5. Customer-oriented and a team player.
6. Hands-on approach.
7. Ability to build and maintain long-term and short-term partnerships.
8. Occasional travel may be required.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Preparation of mRNA-loaded polymeric or lipid nanoparticles using a microfluidic device.
• Evaluation of in vitro and in vivo gene transfection efficiency induced by the nanoparticles via intramuscular injection or subcutenous or i.v. injection.
• In vitro and in vivo toxicity studies.
• In vivo biodistribution studies.
• Participate in maintenance of equipment and procurement of consumables used for this project.
• Participate in lab safety and general housekeeping of the lab

Requirements:

• PhD in drug/gene delivery, pharmaceutical science, biomaterials or biomaterial science
• Familiarity in gene delivery with non-viral nanoparticles
• Highly motivated and able to work independently
• Team player with good interpersonal skills
• Good spoken and written communication skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Join the Institute of Microelectronics (IME) to be immersed in cutting-edge semiconductor research. As a research institute within the Agency for Science, Technology and Research (A*STAR), IME bridges the gap between academia and industry. Our mission is to accelerate innovation in advanced packaging, piezoMEMS, SiC, RF/mmwave GaN, and photonics & sensors, and to develop talent and inspire in Singapore.

We are looking for a passionate individual to lead our Technology-Business Development (Tech-Biz) department. You will be responsible for leading the department to define and implement our strategies for technology-business development, account management, sales and marketing, and ecosystem development. If you"re excited about the future of microelectronics and wish to contribute to the development of Singapore’s innovation engine for microelectronics, we want you on our team!

Job Responsibilities

• Technology-business Development: Lead the department to define and develop strategies for technology translation.
• Customer Relationship Management: Lead the department to win and retain industry partners and customers for high-value and sustainable engagements.
• Sales: Collect, maximise leads and close customer collaboration projects.
• Marketing: Develop and execute marketing strategies to promote IME’s research capabilities to the industry. Represent IME at international conferences and exhibitions.
• Collaborate with Technology Development (TD) Teams: Partner with our "Technology Development" teams to craft robust value propositions for the industry and shape IME’s ‘go-to-market’ strategy. Detect, track and provide market trends and needs for the TD teams.
• Ecosystem Development: Liaise, coordinate and engage effectively with key internal stakeholders, including A*STAR’s Industry and Enterprise Group, other economic agencies and public sector agencies, to align efforts and achieve common goals for the Singapore semiconductor ecosystem.

Job Requirements:

• Degree in Science or Engineering.
• At least 10-15 years of relevant work experience.
• Able to structure and negotiate collaboration agreements.
• Strong communication (written and verbal), marketing and interpersonal skills.
• Strong analytical skills.
• Results oriented, pro-active, and a team player.
• Adaptable and comfortable working in a fast-paced and fast-changing environment.
• Passion to develop Singapore’s semiconductor industry.

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking for a Principal Scientist to join us in our mission to be a leading centre of infectious diseases research. A*STAR IDL aims to develop a cohesive A*STAR response to drive and deliver translational infectious diseases research to better health and economic outcomes.

Job Description:

• Leads conceptual and technical integration of various research studies to provide leading edge solutions in antimicrobial resistance (AMR) research and development
• Conceptualize and create new technologies, patents and publications
• Review and manage operating budget of grants and team
• Establish collaborations, develop scientific proposals and ensure timely achievement of project milestones
• Manage a team and provide scientific and career mentorship to researchers and students

Job Requirements:

• PhD in Biomedical Sciences, Life Sciences, Microbiology, Molecular Biology, Infectious Diseases, Immunology or related field as above
• 4 years of post-PhD relevant experience
• Strong background in Microbiology, Immunology, Molecular Biology, Biochemistry, Genetics and Genomics
• Strong publication record
• Highly motivated and ability to develop strong research ideas to secure grant and funding
• Strong analytical, technical and problem-solving skills
• Team player with good interpersonal skills
• Good spoken and written communication skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description :

We are looking for candidates to join the fusion-energy effort in the newly formed Future Energy Acceleration & Translation (FEAT) Programme, A*STAR. FEAT's plasma physics team focuses primarily on plasma diagnostics, microwave and radiofrequency (RF) heating and current drive (H&CD), and exhaust, with an emphasis on solving the challenges faced by future fusion energy systems. The new hires will be expected to contribute to, and potentially lead, research in magnetic confinement fusion. This includes analytical, computational, and experimental approaches, with the particular emphasis dependent on one's interests and skill set. While the new hires will begin by working on existing projects, participation in grant calls as a principal investigator will be highly encouraged.

We are looking to fill several positions in:

• Plasma diagnostics, including experimental, computational, and AI approaches.
• Theory and simulation of microwave and RF H&CD.
• Theory and simulation of plasma-material interactions, including edge turbulence and transport, sheaths, and sheath-edge coupling.

The key scope of work includes:

• Understanding the physics of fusion plasmas, exhaust, plasma diagnostics, and/or RF H&CD.
• Publishing peer-reviewed papers.
• Writing grants and developing the direction of fusion research in FEAT.
• Supporting local and international collaborators in fusion research.
• Supervising students and interns (optional).

Job Requirements:

• PhD in Physics, Plasma Physics, or equivalent, with a background in magnetic confinement fusion, such as in plasma physics and/or engineering with at least 5 years of relevant experience.
• Deep knowledge in at least one of the followings:
  1. Plasma diagnostics (including hardware experience). Candidates with an experimental inclination will have the opportunity to travel to international collaborators' experiments for extended periods.
  2. Theoretical plasma physics (such as plasma waves, turbulent transport).
  3. Computational plasma physics (such as full-wave, beam tracing, fluid dynamics, gyrokinetics).
• Proficiency in programming languagues such as, but not limited to, Python, C/C++, and Julia.
• Good interpersonal and communication skills both oral and written, ability to adapt and work effectively as a member of a team.
• Resourcefulness and self-motivation with a high degree of professional integrity

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

JOB DESCRIPTION

This job focuses on software development for Software as a Medical Devices. System engineer will be working closely with Project Managers and project teams to ensure the software as a medical device product management Lifecyle is followed thoroughly.

• Support project manager to plan and execute Software as a Medical Device (SaMD) projects including AI applied to healthcare.
• Support technical team in product development, design verification and validation of medical devices including software as medical device.
• Prepare, design and development documentation by working together with software developers, quality and regulatory personnel.
• Prepare project agreements, procurement specifications and technical documents.
• Follow-up on project milestones.

JOB REQUIREMENT

• Preferred to have one year of experience in software development or medical device product development.
• Educational background of computer engineering or bio medical engineering.
• Knowledge in software development, experience in software development environment will be an added advantage.
• Knowledge / willingness to learn the ISO 13485 documentation practices and drive project teams for adherence.
• Good follow up skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A*STAR Strategic Research and Translational Thrusts (SRTTs) are mission-focused programmes in strategic and emerging areas that are cross-disciplinary and of wider strategic interest to A*STAR and Singapore. Set up to address ambitious technological challenges towards impactful outcomes, each SRTT is led by a Programme Director (PD) and is centrally facilitated and supported by A*STAR HQ.

The Future Energy Acceleration and Translation (FEAT) SRTT pioneers next-generation technologies for critical components in extreme environments, thereby addressing today’s industrial challenges and accelerating the realisation of future energy solutions.

Project Manager (PM) and PM Administrator, Strategic Research and Translational Thrust SRTT

Job description:

• Responsible for managing R&D projects and product delivery within FEAT SRTT by planning, organizing, communicating with all FEAT SRTT team members and external stake holders under the guidance of FEAT SRTT Programme Director (PD) and Scientific Programme Manager (SPgM).
• Establish internal and external stakeholder communication & escalation plans, build project / programme schedules, identify and manage major risks, and define clear project / programme deliverables and milestones.
• Assist the FEAT SRTT PD and SPgM to ensure successful delivery of project / programme scope and targets while managing project / programme risk, quality, delivery, scope, schedule, and budget (and project change when required).
• Work with FEAT SRTT scientists and SPgM to bring together grant proposals to secure competitive funding and coordinate cross-project activities, under the guidance of Programme Director as well as Tech-Biz for industry engagements.
• Assist the FEAT SRTT PD and SPgM to manage and implement project / programme changes and interventions to achieve project deliverables and mitigate risk, and to lead, monitor and report the progress of the multiple projects to all internal and external stakeholders.
• Work closely with Tech-Biz officer to support industry engagements and projects, ensuring effective communication throughout the project life cycle.
• Lead and drive solutions for quality, procurement, finance and legal challenges, working closely with the various department and corporate support partners.
• Draft, update and maintain key documents relevant to project lifecycle (if relevant).
• Serve as main administrator of A*STAR project management system (A*PS) to support the roll-out and systematic set up of project management to SRTTs (present and future).
• Guide and train the SRTT project managers to use the A*PS including onboarding.
• Work closely with Central Project Management Office (CPMO), SRTT Programme office, internal colleagues and external stakeholders effectively for execution and implementation of PM processes, policies and projects and assists in the development of best practices of project management.
• Interprets functional A*STAR policies such as project life cycle management, risk management to ensure that plans are aligned to organisation objectives.
• Rollout risk management framework, including Enterprise Risk Management, Business Continuity Management for SRTTs.
• Generate dashboards to regular project reporting as required to management to effectively govern SRTT’s portfolio, programmes, and projects.
• Other exigencies of ad-hoc duties as required

Job Requirements:

• Master or Bachelor in any sciences/project management related discipline.
• Candidates with experience and knowledge in future energy (e.g. nuclear, hydrogen, geothermal) or existing industries (e.g. aerospace, O&G, space, semiconductor) will have an advantage.
• At least 3-5 years of project management experience in technology transfer, product development or research project would be preferable.
• PMP certifications (or equivalent) and experience with Microsoft’s Project System are an advantage.
• Ability to demonstrate a good level of understanding of technical / engineering processes and lead teams throughout the project development cycle.
• Good business acumen, driven to deliver customer requirements and project deadlines.
• Proactive team player and technically motivated to solve problems, innovate and deliver to internal and external customers.
• Good understanding of research administrative and grant processes.
• Experience in managing and roll-out enterprise software is required. Familiarity with PowerBI is a plus.
• Strong planning and analytical skills with an eye for details.
• Strong communicator with excellent interpersonal skills and stakeholder management skills.
• Able to work independently in a diverse environment.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description :

We are looking for candidates to join the fusion-energy effort in the newly formed Future Energy Acceleration & Translation (FEAT) Programme, A*STAR. FEAT's plasma physics team focuses primarily on plasma diagnostics, microwave and radiofrequency (RF) heating and current drive (H&CD), and exhaust, with an emphasis on solving the challenges faced by future fusion energy systems. The new hires will be expected to contribute to, and potentially lead, research in magnetic confinement fusion. This includes analytical, computational, and experimental approaches, with the particular emphasis dependent on one's interests and skill set. While the new hires will begin by working on existing projects, participation in grant calls as a principal investigator will be highly encouraged.

We are looking to fill several positions in:

• Plasma diagnostics, including experimental, computational, and AI approaches.
• Theory and simulation of microwave and RF H&CD.
• Theory and simulation of plasma-material interactions, including edge turbulence and transport, sheaths, and sheath-edge coupling.

The key scope of work includes:

• Understanding the physics of fusion plasmas, exhaust, plasma diagnostics, and/or RF H&CD.
• Publishing peer-reviewed papers.
• Writing grants and developing the direction of fusion research in FEAT.
• Supporting local and international collaborators in fusion research.
• Supervising students and interns (optional).

Job Requirements:

• PhD in Physics, Plasma Physics, or equivalent, with a background in magnetic confinement fusion, such as in plasma physics and/or engineering.
• Deep knowledge in at least one of the followings:
  1. Plasma diagnostics (including hardware experience). Candidates with an experimental inclination will have the opportunity to travel to international collaborators' experiments for extended periods.
  2. Theoretical plasma physics (such as plasma waves, turbulent transport).
  3. Computational plasma physics (such as full-wave, beam tracing, fluid dynamics, gyrokinetics).
• Proficiency in programming languagues such as, but not limited to, Python, C/C++, and Julia.
• Good interpersonal and communication skills both oral and written, ability to adapt and work effectively as a member of a team.
• Resourcefulness and self-motivation with a high degree of professional integrity

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

You will embark on an enriching career journey at the Environmental Health Institute (EHI), and be a member of the Rodent Ecology Section, where your role encompasses the execution of both field and laboratory research. The areas of focus include (i) biosurveillance of the diversity, distribution, and ecology of rodents and their associated pathogens, and (ii) development of integrated mitigation strategies. You will work with stakeholders to translate scientific findings into policy and operations and contribute to the development of national environmental public health policies. As a member of the EHI family, you will have numerous opportunities for personal development, not only in science, but also in other areas such as project management, and stakeholder engagement.

Job Requirements:

• Bachelor's or Master's degree in Ecology, Zoology, or a related life sciences field, preferably with training in public health.
• Experience in designing and conducting research projects, including fieldwork
• Any peer-reviewed scientific publications will be an advantage
• Knowledge in the systematics, biology, ecology, and field surveillance of vectors (including rodents) and their associated pathogens
• Experience in or a willingness to learn animal dissection techniques
• Familiarity with molecular biology techniques and interest in working in high-containment laboratories
• Basic knowledge of biostatistics and use of statistical software
• Possessing a valid class 3 license and willingness to drive NEA's vehicle to field sites is preferred
• Ability to work with multiple stakeholders and contribute to the translation of research into public health policy and operations
• Good organisational, analytical, interpersonal, and communication (written and oral) skills
• Ability to work in a fast-paced environment and to manage multiple tasks
• Self-motivated and eager to learn

Applicants will be updated on the status of their applications within 4 weeks of the closing date of this job posting.

To apply, please proceed to Careers@Gov at https://sggovterp.wd102.myworkdayjobs.com/PublicServiceCareers/job/Singapore/Senior-Principal-Principal-Research-Officer--Rodent-Ecology-Section-_JR-10000026029-1

We are seeking an experienced Bioinformatics Scientist to support new diagnostics product development and support data analytics in software development for Software as a Medical Devices. In this role, you will play a crucial role in driving the successful execution of diagnostic products in collaboration with external partners. The ideal candidate should possess a strong background in bioinformatics and knowledge of biostatistics is highly preferred.

Job Responsibilities:

• Design, development and deployment of latest bioinformatics analysis pipelines for IVD development.
• Design, development and deployment of Bioinformatics pipelines in multi-omics data such as NGS processing, analysis, and reporting for IVD product development
• Provide Bioinformatics analysis support for diagnostics assay product development.
• Provide Biostatistics analysis support for clinical study of diagnostics product development.

Job Requirements:

• PhD or Degree in Computational Biology, Bioinformatics, or a related field, with a strong emphasis on data analytics and machine learning in biological contexts. 1- 2 years of experience or equivalent in industry settings.
• Proficient in working language with Python, R/Matlab. Good knowledge of bioinformatics workflow languages such as Nextflow, Snakemake and Common Workflow Language (CWL).
• Experience with biostatistical analysis and AI machine learning for biomarker identification and predictive model development.
• Experience with Biopython, Bioconductor, Linux and cloud-based deployment is advantageous.
• Knowledge of statistical software such as Minitab, R, SAS/STAT and SPSS, etc. is a plus.
• Experience with IVD (compliance, validation) is a plus.
• Excellent communication and collaboration skills, with experience working independently and in multi-disciplinary teams.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Institute of High Performance Computing (IHPC) was established in April 1998 to provide leadership in high performance computing as a strategic resource for scientific inquiry and industry development. Our mission is to advance science and technology, and develop leading-edge applications through high performance computing and computational science. We have long-term ties with industry partners, including multinational companies and local SMEs, which ensures that our R&D activities stay focused and relevant to real-world needs. We also have active cooperation with the world’s top academics and academic institutions.

Simulation Scientist:

We are looking for a simulation expert who will be part of the team developing a next-generation mobility simulation platform using an agent-based modelling approach. The platform is envisioned to be integrated with other modelling & simulation systems under a digital twin strategy. The responsibilities may include any of the following:

• Develop simulation modules for the agent-based simulator.
• Design and implement simulation scenarios.
• Develop behavioural rules for the simulation agents.
• Implement real-world dynamics including physical motion laws, power-flow, scheduling, and operational constraints as needed.
• Design, calibrate and validate simulation models.
• Optimise the performance of the simulation.
• Write research papers and present at conferences and communicate to project collaborators

Education and experience requirements:

• Ph.D. degree in a related discipline (transportation engineering, operations research, computer engineering/science, or related disciplines)
• At least 2 years of experience
• Strong interests and expertise in traffic simulation, statistical modeling, mathematical programming, reinforcement learning, and optimization
• Minimum of two years of experience in simulation development.

Technical skills:

• Strong proficiency in Java and Python programming languages.
• Familiarity with electrified mobility technologies, electric vehicles, and charging infrastructure.
• Experience with version control systems (e.g., Git).

Experience/familiarity with any of the following is a plus:

• Familiarity with simulation software and tools (e.g., SimPy, MASON, Repast, Simulink, AnyLogic, SUMO).
• Simulation integration standards and frameworks (e.g., HELICS, HLA, DIS).
• High-performance communication technology (e.g., gRPC, MPI, ZeroMQ).

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Institute of High Performance Computing (IHPC) was established in April 1998 to provide leadership in high performance computing as a strategic resource for scientific inquiry and industry development. Our mission is to advance science and technology, and develop leading-edge applications through high performance computing and computational science. We have long-term ties with industry partners, including multinational companies and local SMEs, which ensures that our R&D activities stay focused and relevant to real-world needs. We also have active cooperation with the world’s top academics and academic institutions.

Simulation Scientist:

We are looking for a simulation expert who will be part of the team developing a next-generation mobility simulation platform using an agent-based modelling approach. The platform is envisioned to be integrated with other modelling & simulation systems under a digital twin strategy. The responsibilities may include any of the following:

• Develop simulation modules for the agent-based simulator.
• Design and implement simulation scenarios.
• Develop behavioural rules for the simulation agents.
• Implement real-world dynamics including physical motion laws, power-flow, scheduling, and operational constraints as needed.
• Design, calibrate and validate simulation models.
• Optimise the performance of the simulation.
• Write research papers and present at conferences and communicate to project collaborators

Education and experience requirements:

• Ph.D. degree in a related discipline (transportation engineering, operations research, computer engineering/science, or related disciplines)
• At least 5 years of experience
• Strong interests and expertise in traffic simulation, statistical modeling, mathematical programming, reinforcement learning, and optimization
• Minimum of two years of experience in simulation development.

Technical skills:

• Strong proficiency in Java and Python programming languages.
• Familiarity with electrified mobility technologies, electric vehicles, and charging infrastructure.
• Experience with version control systems (e.g., Git).

Experience/familiarity with any of the following is a plus:

• Familiarity with simulation software and tools (e.g., SimPy, MASON, Repast, Simulink, AnyLogic, SUMO).
• Simulation integration standards and frameworks (e.g., HELICS, HLA, DIS).
• High-performance communication technology (e.g., gRPC, MPI, ZeroMQ).

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Institute of High Performance Computing (IHPC) was established in April 1998 to provide leadership in high performance computing as a strategic resource for scientific inquiry and industry development. Our mission is to advance science and technology, and develop leading edge applications through high performance computing and computational science.

We are looking for highly motivated individuals who are able to work independently and yet are good team players, possess excellent analytical, technical and problem-solving skills, good technical writing and presentation skills. If you share our interests in solving challenging scientific problems using computational science, mathematical methods and/or engineering techniques, we welcome you to apply for the following position.

SYSTEMS SCIENCE DEPARTMENT

Research Scientist (Urban Systems & Transportation modelling)

We are looking for researchers who are highly motivated with a passion for developing solutions relating to modelling and simulation of transportation and complex urban systems. The candidate will join a multidisciplinary team of scientists and engineers to develop next generation transport and urban R&D solutions, leveraging on advanced AI and digital twin technologies. The role is expected to work both internally and externally with collaborators/stakeholders from industry and government agencies.

Requirements

· PhD in Computer Science/Engineering/Computing/Information Systems/Civil Engineering or equivalent

· At least 5 years of experience

· Relevant experience/expertise in at least one of the following areas: Transport system modelling, Agent-based simulation, Geo-spatial analysis, Digital twin

· Strong interests in statistical modelling, optimization, AI

· Proficient in programming languages like Java, Python or C++

· Self-driven and motivated team player

· Curiosity and passion to learn new things

· Good written and verbal communication skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Implementation of HR Policies & Practices

• Understand the Leighton Asia HR Policies and practices defined by the corporate HR function and the organisation’s overall talent strategy.
• Communicate and implement current policies/practices, policy changes and new HR initiatives at project level; Seek support from Head Office (HO).
• Coordinate with respective team leads for allocation of tasks to team members as per plan.
• Analyse movement in volume of requests over time and highlight any downward/upward trend to supervisor for additional resource planning

Recruitment, promotions & transfers

• Review tracker shared by the project teams for open positions
• Coordinate with project teams to identify and promote existing personnel to fill openings prior to external recruitment
• Liaise with the recruitment team to close pending openings in order of criticality
• Identify resource requirements across projects and recommend employees for transfer based on project requirements, past performance of employees and employees’ own preferences
• Coordinate with project teams and HO to complete the transfer process and for appropriate contract extensions/terminations

Performance Management

• Coordinate with project teams to oversee implementations of the performance development review (PDR) process on the projects within stipulated timelines.
• Explain the PDR process in its current form and any changes from the previous cycle, as applicable, to the project teams.
• Share existing process documents, templates, etc.; Oversee timely completion of the process and related documentation/submission.
• Seek support from Project Director to expedite the process in case of any delays.

Training & Development

• Collate Appraisal results and identify training needs of individuals in line with the same
• Create training calendar for each project and share with the Project Director and respective department heads
• Track completion of training programmes via the training calendar; Follow-up with respective project teams and escalate to Project Manager, if required

Grievance handling & employee welfare

• Act as intermediary between employees for dispute resolution; Identify employee grievances on project sites and share the information with the Project Director, departments heads for resolution
• Share relevant information with healthcare providers for prompt & timely healthcare services to personnel
• Coordinate with healthcare providers to obtain “fit to work” certification for personnel post treatment

People management

• Set objective goals, evaluate performance of subordinates and provide them regular feedback
• Identify performance gaps in subordinates and provide necessary support to close such gaps
• Recognize and encourage high performing subordinates
• Train and mentor subordinates on technical as well as behavioral aspects of their respective roles
• Provide opportunities to the team to develop their capabilities

Requirement

• Candidate must possess at least a Diploma, Advanced/Higher/Graduate Diploma, Bachelor's Degree, Post Graduate Diploma, Professional Degree, Human Resource Management, Business Studies/Administration/Management or equivalent.
• At least 5 year(s) of working experience in the related field is required for this position.
• Preferably Executives specializing in Human Resources or equivalent.
• Able to meet deadlines and work under pressure

A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading centre for infectious diseases research. A*STAR IDL aims to develop a cohesive A*STAR response integrated with National PREPARE programme, and to advance translational research in infectious diseases to improve both health and economic outcomes.

The Genetics of Host Immunity Lab at A*STAR IDL focuses on studying the genetic and immunological determinants of life-threatening viral diseases. We are interested in how variants in human genes, or their immunological phenocopies, can predispose patients to severe viral diseases upon exposure to common, yet typically benign viruses. Better understanding of the cause and mechanism of disease that drive the clinical manifestations in patients can guide the development of targeted and effective therapeutic strategies against viral infections.

We are looking for a motivated and dynamic researcher to join us in this adventure. This work will require the selected candidate to work in a BSL-2 and BSL-3 facility.

Job Descriptions:

• Leading projects within the lab including designing and conducting the experiments, performing the analyses and documenting the results, as well as ensuring the timely achievement of project milestones
• Work with patient cohorts and relevant pre-clinical models (both in vitro and ex vivo) of infectious disease in BSL2, BSL2-enhanced and BSL3 facilities
• Participates in collaborations, conducting presentations to research collaborators, including industry partners
• Develop new research techniques, approaches or products that could create new intellectual properties, patents and publications
• Mentoring of students and participation in A*STAR- or Institute-related events

Job Requirements:

• PhD in Genetics, Biomedical Sciences, Microbiology, Immunology, Infectious Diseases or related fields – Candidate with genetics and infectious diseases background would be preferred
• 1-2 years of relevant experience. Candidates with no experience may apply
• Experience in infection/immunity, handling of BSL-2 viral pathogens, iPSC handling, cell culture, flow cytometry, organoid generation, cellular and molecular biology
• Strong analytical, technical, and problem-solving skills
• Demonstrated ability to complete research projects
• Capable of performing effectively in a fast-paced setting
• Highly motivated and able to work independently as well as in a group
• Team player with good interpersonal skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are seeking an experienced Bioinformatics Scientist to support new diagnostics product development and support data analytics in software development for Software as a Medical Devices. In this role, you will play a crucial role in driving the successful execution of diagnostic products in collaboration with external partners. The ideal candidate should possess a strong background in bioinformatics and knowledge of biostatistics is highly preferred.

Job Responsibilities:

• Design, development and deployment of latest bioinformatics analysis pipelines for IVD development.
• Design, development and deployment of Bioinformatics pipelines in multi-omics data such as NGS processing, analysis, and reporting for IVD product development
• Provide Bioinformatics analysis support for diagnostics assay product development.
• Provide Biostatistics analysis support for clinical study of diagnostics product development.

Job Requirements:

• PhD or Degree in Computational Biology, Bioinformatics, or a related field, with a strong emphasis on data analytics and machine learning in biological contexts. 3 - 4 years of experience or equivalent in industry settings.
• Proficient in working language with Python, R/Matlab. Good knowledge of bioinformatics workflow languages such as Nextflow, Snakemake and Common Workflow Language (CWL).
• Experience with biostatistical analysis and AI machine learning for biomarker identification and predictive model development.
• Experience with Biopython, Bioconductor, Linux and cloud-based deployment is advantageous.
• Knowledge of statistical software such as Minitab, R, SAS/STAT and SPSS, etc. is a plus.
• Experience with IVD (compliance, validation) is a plus.
• Excellent communication and collaboration skills, with experience working independently and in multi-disciplinary teams.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Institute of High Performance Computing (IHPC) was established in April 1998 to provide leadership in high performance computing as a strategic resource for scientific inquiry and industry development. Our mission is to advance science and technology, and develop leading edge applications through high performance computing and computational science.

We are looking for highly motivated individuals who are able to work independently and yet are good team players, possess excellent analytical, technical and problem-solving skills, good technical writing and presentation skills. If you share our interests in solving challenging scientific problems using computational science, mathematical methods and/or engineering techniques, we welcome you to apply for the following position.

SYSTEMS SCIENCE DEPARTMENT

Research Scientist (Urban Systems & Transportation modelling)

We are looking for researchers who are highly motivated with a passion for developing solutions relating to modelling and simulation of transportation and complex urban systems. The candidate will join a multidisciplinary team of scientists and engineers to develop next generation transport and urban R&D solutions, leveraging on advanced AI and digital twin technologies. The role is expected to work both internally and externally with collaborators/stakeholders from industry and government agencies.

Requirements

· PhD in Computer Science/Engineering/Computing/Information Systems/Civil Engineering or equivalent

· At least 2 years of experience

· Relevant experience/expertise in at least one of the following areas: Transport system modelling, Agent-based simulation, Geo-spatial analysis, Digital twin

· Strong interests in statistical modelling, optimization, AI

· Proficient in programming languages like Java, Python or C++

· Self-driven and motivated team player

· Curiosity and passion to learn new things

· Good written and verbal communication skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

DxD Hub is an end-to-end productisation partner, committed to transforming the MedTech landscape in Singapore through innovative solutions sourced from both local and regional partners. Our strengths are in cross-disciplinary product development particularly in molecular diagnostics, protein immune assays, and digital diagnostic technologies.

We are seeking a Senior Engineer with system integration expertise with design oversight to join our team. As a vital member of our team, you will be involved in the design, development, and testing of medical devices, ensuring compliance with regulatory standards and industry best practices.

Your role will involve collaborating with cross-functional teams to create innovative solutions encompassing hardware, software and chemistry by conducting verification and validation activities, and providing technical support throughout the product lifecycle.

The ideal candidate will have a solid understanding of system integration principles, best practices in verification and validation testing, and knowledge of medical device regulations (such as ISO 13485).

Join our dynamic team and contribute to the development of cutting-edge medical devices that improve patient care and well-being.

Job Roles and Responsibilities:

• Develop high-level system architectures that meet user requirements while considering design feasibility.
• Ensure that all system components are compatible and can be integrated seamlessly.
• Design and implement integration strategies and validate the functions as intended while adhering to design principles.
• Lead collaborative teams for the design, implementation, and validation while is capable to perform hand-on testing independently if required to complete engineering or verification studies.
• Lead creating innovative solutions that align with both technical specification and user needs for medical products.
• Coordinate between design, engineering, assay, project manager, and other disciplines to ensure cohesive product development.
• Author or oversee the writing of protocols and reports.
• Foster collaboration among team members to address challenges from both a technical and design perspective.
• Creating and maintaining technical documentation, including design specifications, test protocols, and reports, ensuring compliance with regulatory requirements such as ISO 13485.

Job Requirements:

• Experience in system integration and innovation.
• Bachelor’s degree in Engineering, Design or equivalent engineering or science background.
• Comfortable with navigating uncertain situations without clear guideline.
• Adaptability to changing work conditions and project requirements.
• 5-10 years’ experience in cross-functional product development roles and completed one full product development cycle.
• Track record in working effectively with diverse teams, including engineering, design, and marketing.
• Strong interpersonal skills to facilitate communication between technical and non-technical stakeholders and ability to summarize and communicate complex problems in simple terms.
• Strong analytical skills to troubleshoot integration issues while considering design implications.
• Able to break down complex system in simple steps and identify interfaces between modules and generate system diagrams, workflows and reports.
• Curious and proactive approach to gather information necessary for decision-making.
• Knowledge of statistical tools for data analysis such as (Python/Matlab/Origin/LabView) will be a strong advantage.
• Experience with design software. Experience with CFD simulation software such as ANSYS is advantageous.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Summary:

DxD Hub is an end-to-end productisation partner, committed to transforming the MedTech landscape in Singapore through innovative solutions sourced from both local and regional partners. Our strengths are in cross-disciplinary product development particularly in molecular diagnostics, protein immune assays, and digital diagnostic technologies. We are seeking a skilled and experienced Mechanical Design Engineer to join our dynamic team. The successful candidate will take on the responsibility of leading a team in the design and development of mechanical systems. The candidate will work closely with cross-functional teams to lead projects, conducting feasibility studies and overseeing product development. They will also ensure that designs comply with both technical specifications and regulatory standards.

Job Roles and Responsibilities:

• Conceptualise, design, and develop mechanical components and mechanisms for medical devices.
• Responsible for the preparation and maintaining design documentation such as specifications, bill of materials, test protocols, test reports, etc.
• Lead a team to perform structural analysis, thermal analysis, and other relevant tests to validate and optimise designs.
• Responsible for feasibility tests to assess the viability and performance of proposed designs.
• Work closely with cross-functional teams, including teams in molecular diagnostics, protein immune assays, and digital diagnostic technologies as well as electrical engineers, software engineers, and project managers.
• Ensure compliance with DxD Hub Quality Management system, standards, and regulatory requirements such as FDA, ISO13485, etc.

Job Requirements:

• Master’s or bachelor’s degree in mechanical engineering, or related field.
• At least 5 years relevant experience in mechanical design engineering and completed one full product development cycle.
• Three years of experience or equivalent in close and collaborative work with design managers and product managers.
• Experiences in leading a mechanical design team is a plus.
• Proficient in CAD software, such as SolidWorks, AutoCAD, etc.
• Strong understanding of engineering principles, materials, and manufacturing processes.
• Excellent problem-solving and analytical skills.
• Effective communication skills and ability to work collaboratively in a team.
• Knowledge in quality, product verification test, QMS, and ISO13485 would be an advantage.
• Self-driven team player who can work in a fast-paced environment.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody.

Position – Senior Scientist in Pharmacology Unit

CPR is seeking a Ph.D. Scientist with expertise in in vitro and in vivo pharmacology studies. The candidate will also be responsible for disease target validation and have a strong background in the area of oncology. The candidate will lead antibody screening for a drug discovery project. Depending on the experience and opportunity, the candidate will also lead antibody drug discovery project and participate in strategic discussions to advance programs through pipeline.

Responsibility

The applicant should be highly skilled in some of the following areas:

· Design and conduct experiments to investigate novel therapies

· Mentor junior researchers and research associates

· Propose a new drug discovery project

Job Requirements

The applicant should be highly skilled in some of the following areas:

• Proficiency in cell culture techniques with various cell lines
• Expertise in molecular biology techniques (generation of cell lines with overexpression, knockdown, and knockout of a gene, PCR, qPCR, Western blotting, ELISA)
• Experience with flow cytometry and cell sorting
• Knowledge of cell lines and animal models in cancer research
• Primary cell isolation and culture techniques
• Experience with drug discovery research would be highly advantageous
• Three to five years of post-doctoral research experience in oncology would be highly advantageous.

The applicant must have completed and be awarded with a relevant Ph.D. degree in Science or related field (not in the process of achieving it) with 1-2 years of working experience in a related field. In addition, the successful candidates must be able to demonstrate their molecular and cellular biology expertise as evidenced by projects, presentations, or peer-reviewed scientific publications.

Scientists with strong passion in medical science for creating and delivering innovative drugs to society which leads to saving patients suffering from unmet medical needs are highly desired. Familiarity or having prior work experience in antibody drug discovery work will be a plus, although not absolutely necessary. You should also possess good command of spoken and written English, excellent organizational and communication skills, team player mindset, as well as the ability to perform multi-task.

Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to: [email protected]

For more information regarding our Company, you may refer to our website at:

http://chugai-pharmabody.com/

We regret that only short-listed candidates will be notified

Job Responsibilities

• Develop and align strategies to economic and national agenda (e.g. DxD Hub 3.0 in RIE2030 strategy), including strengthening linkages with internal and external stakeholders (e.g. MOH, clinical clusters in setting up satellite programmes).
• Translate overarching DxD Hub’s strategies into an action plan, coordinating across public sector and internal stakeholders and entities to achieve Enterprise’s desired outcomes.
• Set, monitor and report performance and tracking indicators for DxD Hub in alignment with National Platforms Co-ordinating Office and A*STAR Innovation and Enterprise (I&E) division and its operating units and in partnership with finance for financial targets.
• Establish and maintain corporate branding and public awareness of DxD Hub.
• Perform Divisional reporting and communications functions with stakeholders within A*STAR, governing and advisory boards, as well as other public agencies in the ecosystem.
• Review internal operational processes for possible improvements, in alignment with Enterprise and A*STAR best practices.
• Build capabilities of service platforms & drive realization of business outcome.
• Hires, motivates, develops, and retains key talent.
• Develop and deliver accurate reports of operational metrics to the CEO. Deliver monthly operation reports.

Requirements:

• Bachelor’s degree, preferably in Science or Engineering.
• More than 6 years of relevant working experience. Experience in strategic and/or corporate planning would be an advantage.
• Possess strong strategic and analytical thinking skills.
• Able to identify and contextualise stakeholder issues and manage them appropriately.
• Good communication (written and verbal) and interpersonal skills. Able to work in a team and guide the team to achieve their tasks. Able to work outside of organizational boundaries to engage external stakeholders as necessary
• Able to deliver results under tight timelines. Pro-active, quality conscious and results oriented.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The successful candidate will work with PIs Associate Professor Duane Loh and Assistant Professor Tan Yongzi on computational phase retrieval for cryo-electron microscopy of floppy, low-contrast RNA molecules.

The main responsibilities of the position include:

1. Develop realistic forward model to simulate noisy cryo-electron micrographs from RNA biomolecules.
2. Perform computational phase retrieval on 2D micrographs using physics-informed neural networks.
3. Infer structural variability of floppy biomolecules from computationally phase-retrieved micrographs.

Qualifications

Ph.D. in physics-related disciplines.

Experience:

• Fluent in high-performance scientific computing and imaging in python, and comfortable in the Unix environment.

Skills:

• Strong foundation in computational optics, deep learning, high performance computing, and structural biology in cryo-EM