The Experimental Drug Development Centre (EDDC) is at the forefront of advancing Singapore-discovered therapeutic assets from concept to commercialization. We collaborate closely with multidisciplinary teams of scientists to translate cutting-edge research into innovative healthcare solutions.

Responsibilities:

• Evaluate projects entering EDDC’s portfolio by conducting thorough business due diligence.
• Perform market analysis and continuously monitor the competitive landscape as projects progress within our portfolio.
• Foster strong relationships with local and international scientific and business partners crucial to EDDC's success.
• Lead contractual negotiations and participate in commercialization discussions (e.g., out-licensing, co-development) with third parties in collaboration with A* Innovation & Enterprise and A*STAR Legal.
• Represent EDDC and its projects at meetings with external academic and industry partners.
• Attend international industry partnering conferences to connect with potential pharma and biotech partners, showcase EDDC’s drug discovery efforts, and establish strategic partnerships.
• Assist in refining EDDC’s value proposition for drug co-development and venture creation with local and international entities.

Requirements:

• Degree in biology, biochemistry, or related discipline. With additional qualifications in business administration, finance, or a related field will be a plus. Advanced degree (e.g., MBA, PhD) preferred.
• Proven experience in business development within the pharmaceutical or biotechnology industry, including deal-making and strategic partnerships.
• Strong understanding of drug development processes, market dynamics, and intellectual property considerations.
• Excellent communication, negotiation, and interpersonal skills, with the ability to engage effectively with diverse stakeholders.
• Ability to thrive in a dynamic, collaborative environment and manage multiple projects concurrently.
• Experience managing due diligence (including the use of virtual datarooms) and licensing negotiations will be a plus.

About EDDC EDDC is a national platform committed to developing innovative therapies that have the potential to transform patients" lives. Our research and development efforts are focused on understanding the underlying mechanisms of disease and translating these insights into effective treatments. We collaborate with both public sector and industry partners to translate scientific discoveries in Singapore’s biomedical and clinical research into innovative healthcare solutions.

Position Summary

We are seeking a highly motivated Junior Scientist/Scientist I to join our dynamic research team. The ideal candidate will have a strong foundation in chemical biology and thrive in an interdisciplinary research environment. The successful candidate will contribute to cutting-edge research focused on the design, synthesis, and application of small molecule probes for target engagement studies aimed at understanding disease mechanisms and advancing drug discovery.

Job Description

• Plan and execute research experiments under supervision and communicate results and conclusions in group meetings.
• Contribute to ongoing research and development projects in a fast-paced, collaborative environment.
• Maintain detailed and accurate lab notebooks to document research findings.
• Ensure proper upkeep of lab equipment, laboratory supplies, and maintain good housekeeping standards.

Job Qualifications

• A BSc in Chemical Biology is preferred. Applicants with a BSc in Chemistry, Biology, or related disciplines with relevant skill sets may also be considered.

Job Requirements

• Chemistry lab skills: Proficient in the synthesis and purification of compounds (using flash column chromatography, preparative HPLC), and compound characterization techniques (LCMS, HPLC, NMR).
• Biology lab skills: Proficient in cell culture, SDS-PAGE, Western Blot, pulldown and co-immunoprecipitation assays.
• Chemical Biology lab skills: Experience with Activity-Based Protein Profiling (ABPP), Affinity-Based Protein Profiling (AfBP), and chemoproteomics is a plus.
• Candidates without prior experience but with a strong desire and commitment to learn are also encouraged to apply.
• Passion for interdisciplinary research.
• A committed, self-motivated individual with a desire to learn new skills and take on new responsibilities.
• Excellent written and verbal communication skills.
• Strong interpersonal skills, team-oriented with a collaborative spirit and the ability to build relationships internally and externally.

Description:

The Laboratory of Genome Function, led by Dr. Tim Stuart (https://stuartlab.org) at the Genome Institute of Singapore is seeking a postdoctoral fellow interested in single-cell epigenomics. The successful candidate will lead the development of new algorithms and software for the analysis of single-cell genomic data, and lead the application of these methods to analyze and interpret new single-cell datasets.

Requirements:

• Ph.D. in computer science, mathematics, statistics, or a related field. Applicants with a degree in a biological field with strong programming and data analysis experience will also be considered.
• Experience in the analysis of single-cell data
• Ability to program in R, Python, C++, or Rust
• Machine learning experience
• Demonstrated ability to independently lead research projects
• Excellent oral and written communication skills
• Demonstrated ability to publish high-quality research

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Singapore Immunology Network (SIgN), A*STAR, is seeking to appoint an outstanding Senior Principal Scientist to carry out internationally competitive research in Autoimmunity and Inflammatory Diseases.

The research should investigate the pathophysiology of biological pathways and novel pathogenic mechanisms for debilitating disorders, with the aim to translate insights into innovative therapeutic approaches that lead to significant clinical benefits.

The successful candidate is expected to build and maintain a strong research programme that complements the existing programmes at SIgN, and to establish collaborations with the biomedical community and industry. The candidate will also mentor Junior PIs, postdocs and PhD students.

The Senior Principal Scientist position is equivalent to that of an Associate/Full Professor in the university system. The successful candidate can look forward to a competitive salary package and resources as well as a dynamic work environment. Although part of the research programme will be supported by core funding, the candidate is expected to expand his/her research activities by securing additional funds through the various grant schemes available in Singapore and abroad.

Job Responsibilities:

• To lead a research team to conduct experimental research in the areas of Autoimmunity and Inflammatory Diseases.
• To initiate and execute novel research projects, to translate research outputs into clinical or industrial collaborations
• To write up high impact research publications
• To mentor and provide support to junior researchers

Job Requirements:

• PhD in Immunology, Microbiology, Biomedical Sciences, or other relevant disciplines
• More than 8 years’ experience in independent research and leading a research group
• Strong lab-based research background in Immunology and Microbiology
• An excellent track record of research publications
• Excellent written and spoken communication skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Biological Resource Centre (BRC) is an AAALAC International accredited and bizSAFE Level 3 certified laboratory animal facility that provides high quality animal housing and animal support services. BRC is seeking an Associate (Administration) to join us to support the administrative duties.

Job Description

• Working closely with Finance and assist in billing of customers.
• Follow up with customers on overdue invoices.
• Communicate with customers/vendors via phone, email or personally and investigate and resolve customer queries.
• Performance of Good Receipt.
• Maintain and update booking system details when needed.
• Collation of information for Management.
• Assist with Management / Financial reporting.
• Preparation of presentation slides.
• Carry out other duties and tasks that may be assigned from time to time.

Job Requirements:

• Diploma in Business or Accountancy, or equivalent.
• Proficient in Microsoft Office (e.g. Outlook, Word, Excel, PowerPoint).
• Excellent interpersonal and communication skills, meticulous.
• Ability to break down tasks into deliverables and set realistic timelines for completion.
• Ability to work independently and collaboratively in teams.
• Excellent spoken & written communication skills.
• Knowledge of SAP system will be advantageous.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Experimental Drug Development Centre (EDDC) is at the forefront of advancing Singapore-discovered therapeutic assets from concept to commercialization. We collaborate closely with multidisciplinary teams of scientists to translate cutting-edge research into innovative healthcare solutions.

Responsibilities:

• Evaluate projects entering EDDC’s portfolio by conducting thorough business due diligence.
• Perform market analysis and continuously monitor the competitive landscape as projects progress within our portfolio.
• Foster strong relationships with local and international scientific and business partners crucial to EDDC's success.
• Lead contractual negotiations and participate in commercialization discussions (e.g., out-licensing, co-development) with third parties in collaboration with A* Innovation & Enterprise and A*STAR Legal.
• Represent EDDC and its projects at meetings with external academic and industry partners.
• Attend international industry partnering conferences to connect with potential pharma and biotech partners, showcase EDDC’s drug discovery efforts, and establish strategic partnerships.
• Assist in refining EDDC’s value proposition for drug co-development and venture creation with local and international entities.

Requirements:

• Degree in biology, biochemistry, or related discipline. With additional qualifications in business administration, finance, or a related field will be a plus. Advanced degree (e.g., MBA, PhD) preferred.
• Proven experience in business development within the pharmaceutical or biotechnology industry, including deal-making and strategic partnerships.
• Strong understanding of drug development processes, market dynamics, and intellectual property considerations.
• Excellent communication, negotiation, and interpersonal skills, with the ability to engage effectively with diverse stakeholders.
• Ability to thrive in a dynamic, collaborative environment and manage multiple projects concurrently.
• Experience managing due diligence (including the use of virtual datarooms) and licensing negotiations will be a plus.

The role will be part of the Singapore Aerospace Programme (SAP) team to manage research projects performed by A*STAR Research Entities for industry partners, manage programme activities and handle industry engagement activites.

Key responsibilities include:

Programme management

• Assist in the planning and execution of new project launches including the call for problem statements, workshops and proposal/technical reviews
• Monitor on-going projects through regular review meetings with research teams to ensure budget and deliverables are met
• Manage report submissions and variation requests
• Assist in the planning and execution of 6-monthly Programme Management Committee (PMC) meetings
• Work with teammates to ensure the smooth operations of the programme
• Support other office functions, e.g. hosting industry events

Stakeholder engagement and development

• Participate in meetings with SAP consortium members, industry stakeholders and public agencies
• Assist in the planning and execution of Singapore Airshow exhibition and hosting of Singapore Aerospace Technology Leadership Forum
• Facilitate the conceptualization and development of follow-on research initiatives beyond SAP
• Work with inter-division or inter-agency teams to drive aerospace industry development, develop industry transformation maps and aerospace roadmaps
• Coordinate industry engagement activities such as company visits to A*STAR and Airshow meetings and manage follow-up actions
• Nurture industry accounts to deepen research activities with A*STAR
• Engage Institutes of Higher Learning (IHLs) to jointly develop research ecosystem aerospace capabilities

Job Requirements

• Bachelor of Engineering, preferably in the field of aerospace or aeronautical
• 8 years of relevant experience, preferably in aerospace MRO or R&D and/or project management roles
• Strong communication skills
• Strong interpersonal skills
• Strong planning and analytical skills
• Result-oriented, resourceful and attentive to details
• Familiarity with the Singapore research ecosystem and grant call process will be an advantage

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The role will be part of the Singapore Aerospace Programme (SAP) team to manage research projects performed by A*STAR Research Entities for industry partners, manage programme activities and handle industry engagement activites.

Key responsibilities include:

Programme management

• Assist in the planning and execution of new project launches including the call for problem statements, workshops and proposal/technical reviews
• Monitor on-going projects through regular review meetings with research teams to ensure budget and deliverables are met
• Manage report submissions and variation requests
• Assist in the planning and execution of 6-monthly Programme Management Committee (PMC) meetings
• Work with teammates to ensure the smooth operations of the programme
• Support other office functions, e.g. hosting industry events

Stakeholder engagement and development

• Participate in meetings with SAP consortium members, industry stakeholders and public agencies
• Assist in the planning and execution of Singapore Airshow exhibition and hosting of Singapore Aerospace Technology Leadership Forum
• Facilitate the conceptualization and development of follow-on research initiatives beyond SAP
• Work with inter-division or inter-agency teams to drive aerospace industry development, develop industry transformation maps and aerospace roadmaps
• Coordinate industry engagement activities such as company visits to A*STAR and Airshow meetings and manage follow-up actions
• Nurture industry accounts to deepen research activities with A*STAR
• Engage Institutes of Higher Learning (IHLs) to jointly develop research ecosystem aerospace capabilities

Job Requirements

• Bachelor of Engineering, preferably in the field of aerospace or aeronautical
• 5 years of relevant experience, preferably in aerospace MRO or R&D and/or project management roles
• Strong communication skills
• Strong interpersonal skills
• Strong planning and analytical skills
• Result-oriented, resourceful and attentive to details
• Familiarity with the Singapore research ecosystem and grant call process will be an advantage

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

About EDDC EDDC is a national platform committed to developing innovative therapies that have the potential to transform patients" lives. Our research and development efforts are focused on understanding the underlying mechanisms of disease and translating these insights into effective treatments. We collaborate with both public sector and industry partners to translate scientific discoveries in Singapore’s biomedical and clinical research into innovative healthcare solutions.

Position Summary

We are seeking a highly motivated Junior Scientist/Scientist I to join our dynamic research team. The ideal candidate will have a strong foundation in chemical biology and thrive in an interdisciplinary research environment. The successful candidate will contribute to cutting-edge research focused on the design, synthesis, and application of small molecule probes for target engagement studies aimed at understanding disease mechanisms and advancing drug discovery.

Job Description

• Plan and execute research experiments under supervision and communicate results and conclusions in group meetings.
• Contribute to ongoing research and development projects in a fast-paced, collaborative environment.
• Maintain detailed and accurate lab notebooks to document research findings.
• Ensure proper upkeep of lab equipment, laboratory supplies, and maintain good housekeeping standards.

Job Qualifications

• A BSc in Chemical Biology is preferred. Applicants with a BSc in Chemistry, Biology, or related disciplines with relevant skill sets may also be considered.

Job Requirements

• Chemistry lab skills: Proficient in the synthesis and purification of compounds (using flash column chromatography, preparative HPLC), and compound characterization techniques (LCMS, HPLC, NMR).
• Biology lab skills: Proficient in cell culture, SDS-PAGE, Western Blot, pulldown and co-immunoprecipitation assays.
• Chemical Biology lab skills: Experience with Activity-Based Protein Profiling (ABPP), Affinity-Based Protein Profiling (AfBP), and chemoproteomics is a plus.
• Candidates without prior experience but with a strong desire and commitment to learn are also encouraged to apply.
• Passion for interdisciplinary research.
• A committed, self-motivated individual with a desire to learn new skills and take on new responsibilities.
• Excellent written and verbal communication skills.
• Strong interpersonal skills, team-oriented with a collaborative spirit and the ability to build relationships internally and externally.

The Singapore Immunology Network (SIgN), A*STAR, is seeking to appoint an outstanding Senior Principal Scientist to carry out internationally competitive research in Autoimmunity and Inflammatory Diseases.

The research should investigate the pathophysiology of biological pathways and novel pathogenic mechanisms for debilitating disorders, with the aim to translate insights into innovative therapeutic approaches that lead to significant clinical benefits.

The successful candidate is expected to build and maintain a strong research programme that complements the existing programmes at SIgN, and to establish collaborations with the biomedical community and industry. The candidate will also mentor Junior PIs, postdocs and PhD students.

The Senior Principal Scientist position is equivalent to that of an Associate/Full Professor in the university system. The successful candidate can look forward to a competitive salary package and resources as well as a dynamic work environment. Although part of the research programme will be supported by core funding, the candidate is expected to expand his/her research activities by securing additional funds through the various grant schemes available in Singapore and abroad.

Job Responsibilities:

• To lead a research team to conduct experimental research in the areas of Autoimmunity and Inflammatory Diseases.
• To initiate and execute novel research projects, to translate research outputs into clinical or industrial collaborations
• To write up high impact research publications
• To mentor and provide support to junior researchers

Job Requirements:

• PhD in Immunology, Microbiology, Biomedical Sciences, or other relevant disciplines
• More than 10 years’ experience in independent research and leading a research group
• Strong lab-based research background in Immunology and Microbiology
• An excellent track record of research publications
• Excellent written and spoken communication skills

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description

• Develop, validate and perform bioassays and bioanalytical assays in compliance with FDA/EMA and GLP guidelines
• Refine current method in response to changing requirements of drug development
• Prepare study plan and study data of assays performed
• Analyse and present data/results
• Document work, results, analyses and findings in laboratory notebooks or study folders as appropriate according to workflow
• Draft SOPs and study reports
• Perform literature review for various drug pipelines and assays as required
• Meet project milestones with set quality
• Ensure scientific integrity of studies conducted and reports submitted

Requirements

• BSc or MSc in biomedical science, life science or equivalent
• Prior research and development experience are required
• Proficient in mammalian cell culture and aseptic techniques is a must
• Experience in ligand binding assays mainly ELISA, cell-based assays, SDS-PAGE, western blot and reporter assays is highly desirable
• Good knowledge of cell based (potency) or ligand binding assays required in drug development process
• Proficient with office software (MS office, Teams), and familiar with statistical tools (Graphpad Prism, XLSTAT or PLA)
• Knowledge of bioassays, bioanalytics and its method validation, GLP and ISO17025 is a plus
• Good written and verbal communication skills
• Superior problem solving and troubleshooting skills, attention to details
• Good interpersonal skills

Job Description

The Centre for Ageing Research and Education (CARE) is an academic research centre in Duke-NUS Medical School. Drawing on its multidisciplinary expertise and collaborations across medical, social, psychological, economic, and environmental perspectives, CARE’s research is situated in eight broad thematic areas: Population Health, Family Caregiving, Community-Based Health and Social Care Services, Productive Ageing, Falls, Ageing and the Environment, Health Communication, and Social and Psychological Aspects of Ageing.

CARE is a vibrant centre with individuals from diverse academic and personal backgrounds, and values the energy, passion, and thought leadership of promising scholars who desire to achieve health, social inclusion, and a high quality of life for older adults in Singapore. At Duke-NUS, CARE works closely with the Health Services and Systems Research (HSSR) Signature Research Programme, a centre of academic excellence for research and education on the organisation, funding and delivery of health services, and a focus is on public health and clinical service innovation in an increasingly complex and connected world.

We are seeking a full-time Research Assistant to join the team. The selected candidate will work across research projects, with the primary responsibilities including but not limited to the following:

• Perform data management including data cleaning, quality and consistency checks, and preparation of codebooks.
• Work with other researchers on interpreting and analysing quantitative data.
• Contribute to preparation of reports, policy and research briefs, presentations, and research papers.
• Conduct follow-up assessments of study participants over the phone.
• Support other project management tasks.
• Assist with other initiatives at CARE where required.

Job Requirements

• Bachelor’s Degree in Sociology, Epidemiology, Gerontology, Public Health, Psychology, Social Work, or other related disciplines.
• Prior work experience in quantitative data analysis will be advantageous.
• Possess strong communication and interpersonal skills.
• Able to take initiatives to learn on the job and manage assigned tasks.
• Motivated and detail-oriented with the ability to work independently as well as with others in a multi-disciplinary setting.

Candidates with relevant work experience may be considered for a Research Assistant (Senior) position.

Please attach a cover letter and a CV, with names and contact information of 3 referees. Applications will be reviewed on a rolling basis. We regret that only shortlisted applicants will be notified.

Essential duties and responsibilities for this position include:

• The candidate will work together with a multidisciplinary research team to develop the quantum optical characterization setups, such as g(2) measurements, entangled photon measurements
• Optical characterizations of the fabricated quantum optical & nanophotonic devices.
• Data processing, programming, and automation of characterization setups
• Scientific dissemination (journal papers, conferences, and patents)

The detailed job requirements:

• A PhD Degree in physics/quantum optical characterization
• Strong publication track record
• Strong foundation knowledge in quantum optical characterization.
• Strong capability with optical alignment and optical characterization is an essential requirement.
• Self-motivated and passionate on research work
• Possess good critical thinking and problem-solving skills
• Good team player
• Excellent oral and written communication skills
• Applicants with no minimum work experience may apply

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description

We are looking for talented wet-lab Research Fellow to work with a multidisciplinary group of scientists on the discovery of new targets for therapy in Diabetic Nephropathy (DN), a devastating complication of diabetes causing significant morbidity, mortality and human suffering. In Singapore, the incidence of DN as a cause of end-stage kidney disease is among the highest in the world. The job will be part of the NMRC-funded project called Diabetes Study in Nephropathy and other Microvascular Complications II, and it will be based within the Centre for Computational Biology (CCB). This position will be for a period of 3 years, with possible extension depending on work performance and funding availability.

The selected candidate will perform a variety of research activities, which include planning, organising and conducting research studies within the overall scope of a research project under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Contribute to occasional educational / instructional activities and project management.
• Provide guidance and mentorship to undergraduate / medical students and research assistants.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in a related scientific area (e.g., Life Sciences/Biomedical Sciences, Pharmacology). Candidates with higher credentials may be considered for Senior Research Fellow appointment.
• Hands-on experience with transgenic models (breeding and maintenance) and surgery.
• Experience with rodents (mice/rats) phenotyping, including metabolic traits, biochemistry, histology and microscopy.
• Hands-on experience with wet-lab techniques in molecular and cell biology, including familiarity with primary cell cultures and inflammatory and metabolic cellular assays.
• Possess knowledge and experience in pharmacology and pharmacokinetics.
• Have a system-level understanding of human cardiometabolic pathology.
• Proven track record in the form of peer-reviewed research publications.
• Demonstrated capability of research independence progressively.
• Possess strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will play a key role in a natural products-based drug discovery program, conducting analytical chemistry, bioassays, compound management, molecular and cell biology, and biochemistry laboratory experiments under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Support all aspects of the research project.
• Conduct extractions and fractionation of natural products.
• Execute cancer and other mammalian cell culture assays.
• Carry out antibacterial and antifungal assays and assist with microscopy imaging of cells.
• Perform molecular and phenotypic analyses to understand mechanism of action.
• Conduct accurate monitoring, documenting and reporting of experimental results and/or research findings.
• Assist with general upkeep of laboratory needs, procurement of reagents, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described therein.

Job Requirements

• Bachelor’s or Master’s Degree in Analytical Chemistry, Chemical Biology, Pharmacology, or other related fields. Candidates with higher credentials may be considered for the Research Assistant (Senior) position.
• Familiar with organic and analytical chemistry techniques, including chromatography and HPLC.
• Demonstrated knowledge and possesses experience in cell and molecular biology techniques such as cell culture, western blot, RNA and DNA isolation, and RT-qPCR.
• Strong interpersonal communication skills with excellent written, and computer skills.
• Well-organised and excellent record keeping skills are a must.
• A strong team player who is open-minded, energetic, highly motivated and can work collaboratively in an interdisciplinary team and diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will play a key role in a natural products-based drug discovery program. He/she will work both independently and collaboratively to analyse complex natural products using NMR and mass spectrometry, including metabolomic profiling to identify potential molecular targets and mechanisms.

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Source financial support for research activities by investigating potential sources of funding, collaborate with Principal Investigator to write and revise grant/fellowship applications.
• Provide guidance and mentorship to junior researchers.
• Ensure optimal progress of experiments in the laboratory by conducting, supervising, and evaluating laboratory procedures and outcomes. Revise and analyse targets to obtain high-quality and reproducible results.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in Chemistry, Chemical Biology, or related discipline with 2 years of relevant post-doctoral experience.
• Demonstrate general expertise in the field of natural products isolation, metabolomics, and global profiling.
• Strong NMR and mass spectrometry skills in compound characterisation.
• Familiar with database and networking platforms for dereplication (e.g., GNPS).
• Proven track record in the form of high impact publications.
• Strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Cardiovascular and Metabolic Disorders (CVMD) Programme at Duke-NUS houses state-of-the-art technologies for profiling mitochondrial function and metabolic adaptations in model organisms and undertakes translational research in cardiovascular and metabolic disorders. The program has a strong track record of publication in top-tier journals, successful commercialisation efforts leading to spin-offs, as well as nurturing early career researchers into independent academic or industry positions.

Metabolic dysfunction-associated steatohepatitis (MASH) is a severe metabolic liver disease that can affect up to 6.5% of the adult population, with only one FDA-approved drug. Dr. Jin Zhou’s team is specialised in studying the novel molecular pathogenesis underlying MASH for the identification of new druggable targets. The lab uses a combination of biochemistry, genetics, animal modeling, and metabolomics approaches to understand cellular processes related to mitochondrial function and hepatic lipid metabolism.

We are looking for a highly self-motivated Research Fellow to join the team. The selected candidate will perform a variety of research activities, including but not limited to the following:

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Maintain accurate and complete records of all findings and ensure the validity and reliability of data at all times.
• Present research outcomes orally, and draft research abstracts and manuscripts for publication.
• Provide guidance and mentorship to undergraduate/medical students and research assistants.
• Perform other related duties incidental to the work described herein.

Job Requirements

• PhD in Biomedical Sciences, Molecular Biology, Cell Biology, Pharmacology, or related disciplines.
• Hands-on experience with mice models, as well as wet-lab techniques in molecular and cell biology. Prior experience in polysome and/or ribosome profiling would be advantageous.
• Proven track record of academic publications, including writing/drafting first-author papers.
• Demonstrate excellent communication, technical independence, and analytical and problem-solving skills.
• Self-motivated individual, enthusiastic to take initiative, and able to work independently and collaboratively in a team.

We regret that only shortlisted candidates will be notified.

Job Description

The laboratory of Dr. Tang Hong-Wen within the Signature Research Programme in Cancer and Stem Cell Biology (CSCB) at Duke-NUS is recruiting a Research Assistant with strong enthusiasm and interest in muscles and muscle stem cells. The Tang lab’s scientific focus is to understand how muscle functions get impaired during aging and tumorigenesis. Dr Tang’s laboratory uses unique cross-species and interdisciplinary approach incorporating Drosophila genetics, biochemistry, cell biology, and mouse models, to identify new evolutionary conserved mechanisms underlying human muscle diseases and provide new therapeutic strategies targeting muscle wasting and mitigating the effects of aging.

The selected candidate will perform a variety of functions related to research under the supervision of the Principal Investigator or his/her designate: -

• Perform tasks and support all aspects of the research project.
• Conduct accurate monitoring, documenting and reporting of experimental results and research findings.
• Evaluate and interpret collected data and prepare oral presentations or written reports/ scientific manuscripts/literature for publication and analyses setting forth progress, adverse trends and appropriate recommendations or conclusions.
• Contribute to some project management, provision of guidance to undergraduate/medical students.
• Assist with general upkeep of laboratory needs, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described herein.

Job Requirements

• Bachelor’s Degree in Sciences / Life Sciences.
• Demonstrated basic knowledge, skills and expertise in supporting various research activities.
• Knowledge of the scientific background relevant to the research area.
• Laboratory experimental skills.
• A strong team player who is open-minded, energetic, highly motivated and can work collaboratively in an interdisciplinary team and diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Laboratory for Translational and Molecular Imaging (LTMI), Duke-NUS Medical School, is recruiting a Research Fellow/Senior Research Fellow to lead state-of-the-art small animal imaging studies in Viral Infectious Disease. LTMI aims to develop local infrastructure and deep capabilities in the development of molecular imaging technologies for guiding the advancement and translation of new imaging biomarkers to guide novel therapeutics in viral infectious disease.

The successful candidate will lead pre-clinical imaging efforts to validate novel imaging probes that target potential biomarkers of viral infection and host response. He/She will be responsible for the strategic planning, execution and communication of research. Candidates with strong records of scientific accomplishment in radiopharmaceutical sciences, immunology or related disciplines are encouraged to apply.

Lead mouse model development and characterisation of viral disease.

• Perform in vivo characterisation of imaging probe specificity and sensitivity with PET/CT, SPECT/CT and/or optical imaging in combination with different treatment regimes.
• Monitor immune response to anti-viral, and vaccines with longitudinal imaging, supported with pathology (IHC/IF), and cellular assessment (flow cytometry).
• Ensure regulatory compliance of research, including legal and ethical requirements.
• Ensure timely reporting and presentation of study results to the team, and making appropriate decisions on data obtained from imaging studies.
• Write and review research papers, and present at local and international conferences.
• Provide guidance and mentorship to junior researchers and/or graduate students.
• Demonstrate effective organization/project management abilities to efficiently manage time and work activities.

Job Requirements

• PhD in Virology/Immunology/Radiopharmaceutical Sciences or related disciplines.
• Experience in multimodality imaging and image analysis (including PET, SPECT, CT, fluorescence, and/or optical imaging) within the infectious diseases and immunology domain.
• Background in virology, molecular biology, cell biology and oncology.
• Possesses experience in mouse studies (injection, anatomy, necropsy, pathology) required.
• Proven track record of academic publications, including writing/drafting first author papers.
• Self-motivated individual, enthusiastic to take initiatives, as well as able to work independently and collaboratively in a team.
• Demonstrate excellent communication, technical independence, analytical and problem-solving skills.

We regret that only shortlisted candidates will be notified.

Job Description

The Cardiovascular and Metabolic Disorders (CVMD) Programme houses state-of-the-art technologies for profiling mitochondrial function and metabolic adaptations in human patients and other model organisms, and undertakes translational and clinical research in cardiovascular and metabolic disorders.

Prof Derek Hausenloy’s laboratory aims to discover new treatments for protecting the heart from acute ischaemia/reperfusion injury and for preventing heart failure. We use a translational approach to research comprising cell models, rodent models (atherosclerosis, acute myocardial infarction and heart failure), nanoparticles for delivery of therapeutics to the ischaemic heart, and clinical studies.

The selected candidate will perform a variety of functions related to research under the supervision of the Principal Investigator or his/her designate, including but not limited to the following: -

• Perform tasks and support all aspects of the research project.
• Conduct accurate monitoring, documenting and reporting of experimental results and/or research findings.
• Evaluate and interpret collected data and prepare oral presentations or written reports/ scientific manuscripts/literature for publication and analyses setting forth progress, adverse trends and appropriate recommendations or conclusions.
• Assist researchers in contributing to some aspects of the project management, occasional laboratory demonstrations and in providing guidance to undergraduate/medical students.
• Establish work procedures to maintain high efficiency and productivity of the laboratory. Assist with general upkeep of laboratory needs, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described herein.

Job Requirements

• Bachelor / Master’s Degree in Sciences/Life Sciences with at least 2 years of relevant work experience in the design and conduct of experimental projects.
• Demonstrated good knowledge, skills and expertise in supporting various research activities including molecular biology, cellular assay, ELISA, and histology.
• Knowledge of the scientific background relevant to the research area.
• Laboratory experimental skills.
• Experience with cardiovascular research and animal work (rodents) preferred.
• A strong team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.
• RCULA certification will be an advantage.

We regret that only shortlisted candidates will be notified.

As the Research Engineer (Equipment/Operations), you are directly involved in tool installation activities for semiconductor process tools. You would need to work proactively to coordinate with the contractor on the ground for the execution and take corrective and preventive actions of lessons learned, due diligently to prevent reoccurrence. You are responsible for performing utilities turn-on after installation is completed. You must perform the activities per ASTAR site procedure and safety policies to ensure all tool-install-related activities are completed, meeting safety, quality, schedule and budget requirements. You will also be required to perform other activities such as operations for the different semiconductor modules (Diffusion, Litho, Dry/Wet Etch, Thin Film, Implant, etc).

Responsibilities:

• Coordinate with all tool-install base contractors to execute equipment hookup for new tools, to meet the high-quality standards, dynamic schedule, and forecasted budget.
• Coordinate with the Project owner (NGTC/APM) to facilitate utility release as per the planned schedule and update tool release status timely
• Follow all safety and environmental procedures to ensure compliance with EHS-related regulations, risk assessment, safe work procedures, and permit-to-work system.
• Play an active role in safety, actively participating in safety discussions and safe work practices.
• Establish regular area walks to identify opportunities for improved safety, cleanliness, housekeeping and efficiency
• Establish regular, working interaction with peers as well as vendors in tool installation & facilitation, communicating clearly and respectfully all relevant information.
• Keep the reporting officer informed regarding the progress of assigned work and any abnormalities observed in your area.
• Demonstrate ability to understand drawing and highlighting discrepancies
• Follow area-specific procedures and documentation
• Prioritize work tasks to meet schedule and expectations, minimum guidance
• Perform tool tool-relativities and cleanroom systems troubleshooting during the hookup phase
• To perform equipment trouble-shooting of the equipments in NGTC when the need arises
• To perform utility-on after installation completion and to work closely with LCAM for complete closure
• To perform tests balancing of exhaust for new tools whenever necessary
• To perform measures for tool consumption during the hookup phase and to work closely with LCAM
• Use methods to organize, calculate, and display data accurately for utility and flowrate measurement
• Perform site activities in accordance to the Discipline

Requirements:

• Degree/Diploma in Mechanical/Electrical/Chemical engineering or equivalent
• Semiconductor experience (Equipment & Process)
• Facilities field or Wafer Fab Manufacturing equipment background will be an advantage.
• AutoCAD

Job Description:

• Actively working with cross functional stakeholders to plan and develop new lithography process
• Validate mask designs, reticle tape out and post tape out verifications
• Actively participate in internal and external technical discussions to overcome process related challenges and provide relevant solutions
• Perform process characterization, margin study to determine the process capability of new process platform
• Act as subject matter expert and resource for researchers and industry partners to enable process and/or product realization
• Publish process development outcomes and breakthroughs in research community
• Engage with relevant equipment makers/vendors and responsible for selecting and procuring research equipment
• Work with fab team in establishing SPC for newly developed processes

Job Requirements:

• Bachelors/Masters in Materials Science and Engineering, Physics, Electrical Engineering, or closely related fields are welcome to apply
• More than 5 years of relevant working experience in R&D and/or industry environment and broad exposure in handling 6”, 8” and/or 12” substrate covering nano to micron technology nodes, preferably in SiC/GaN/Photonics
• Proficient in Photolithography tools including Immersion/KrF/I-line Scanner/Stepper/Mask Aligner, knowledge in eBeam Lithography tool will be added advantage
• Hands-on experience in metrology including but not limited to CdSEM, Overlay, OCD, DRSEM, Microscope. Capable to create recipe to support various research requirements
• Knowledge in design and simulation (ProLith, OPC,etc), and reticle layouts (OAS,GDS) review and basic tape out process
• Equipped with Photolithography skill set including fundamental lithography theory, Photoresist characteristic and application, new process setup (swing curve, FEM, DoE, Statistic Root Cause Analysis and problem solving methodology, etc), optimization and margin improvement.
• Relevant hardware and application knowledge in Photolithography tools and metrology.
• Possess good interpersonal and oral/written communication skills, with ability to deliver clear and concise messages to both internal and external stakeholders.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The National University of Singapore invites applications for the position of Research Assistant in the Department of Information Systems and Analytics, School of Computing. The School of Computing is strongly committed to research excellence in all its dimensions: Searching for fundamental results and insights, developing novel computational solutions to a wide range of applications, building large-scale experimental systems and improving the well-being of society. We seek to play an active role both internationally and locally in the core and emerging areas of Computer Science and Information Systems.

The Research Assistant will be responsible for working closely with the Principal Investigator and lab members on one or more research projects. He/she should possess experience or interest in at least one of the following research areas:

Key responsibilities:

• Build a tree based private blockchain system for the given specification. It is a tree structure with hash based dependency for validation similar to blockchain.
• Evaluate the tree based system for efficiency, accuracy, scalability, throughput and energy efficiency through simulations with varying data complexities.
• Build an application using the tree based structure and gather insights from users, developers or businesses leveraging BlockForest, focusing on ease of usage/integration and practical benefits.

Only shortlisted candidates will be notified.

Job Requirements

• A Bachelor’s degree with Honours in Computer Science or related area;
• Good knowledge in Blockchain technologies; and
• Experience in research

Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, and other new antibody engineering technologies that are under development.

Research Assistant – Mid-size Molecule Unit

Job Scope:

· Peptide screening - ELISA, bead-based separation etc.

· DNA/RNA analysis - primer design, PCR, qPCR, purification (spin column, magnetic beads, ethanol precipitation, phenol chloroform extraction etc.), electrophoresis (Agarose gel, Urea-PAGE), NGS(Illumina) etc.

· Protein analysis - SDS-PAGE, western blotting, ELISA etc.

Requirements

· Lead identification screening in drug discovery

· Antibody, protein or peptide engineering

· Biopanning, such as phage display, SELEX, in vitro compartmentalization, microfluidics

· RNA-related analytics, protein purification, NGS data analysis, Biomek operation, etc.

· Degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Molecular Biotechnology with 1-2 years of working experience in a related field.

· Fresh graduates are welcome to apply.

Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to: [email protected]

For more information regarding our Company, you may refer to our website at:

http://chugai-pharmabody.com/

We regret that only short-listed candidates will be notified

Job Description:

• Actively working with cross functional stakeholders to plan and develop new lithography process
• Validate mask designs, reticle tape out and post tape out verifications
• Actively participate in internal and external technical discussions to overcome process related challenges and provide relevant solutions
• Perform process characterization, margin study to determine the process capability of new process platform
• Act as subject matter expert and resource for researchers and industry partners to enable process and/or product realization
• Publish process development outcomes and breakthroughs in research community
• Engage with relevant equipment makers/vendors and responsible for selecting and procuring research equipment
• Work with fab team in establishing SPC for newly developed processes

Job Requirements:

• Bachelors/Masters in Materials Science and Engineering, Physics, Electrical Engineering, or closely related fields are welcome to apply
• More than 5 years of relevant working experience in R&D and/or industry environment and broad exposure in handling 6”, 8” and/or 12” substrate covering nano to micron technology nodes, preferably in SiC/GaN/Photonics
• Proficient in Photolithography tools including Immersion/KrF/I-line Scanner/Stepper/Mask Aligner, knowledge in eBeam Lithography tool will be added advantage
• Hands-on experience in metrology including but not limited to CdSEM, Overlay, OCD, DRSEM, Microscope. Capable to create recipe to support various research requirements
• Knowledge in design and simulation (ProLith, OPC,etc), and reticle layouts (OAS,GDS) review and basic tape out process
• Equipped with Photolithography skill set including fundamental lithography theory, Photoresist characteristic and application, new process setup (swing curve, FEM, DoE, Statistic Root Cause Analysis and problem solving methodology, etc), optimization and margin improvement.
• Relevant hardware and application knowledge in Photolithography tools and metrology.
• Possess good interpersonal and oral/written communication skills, with ability to deliver clear and concise messages to both internal and external stakeholders.