Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 5 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Key Responsibilities:

• Provide scientific and technical expertise to lead a research team to develop capabilities in ingredient fermentation
• Develop mechanistic understanding of the microbiology of fermentation
• Develop research proposals and seek research fundings
• Disseminate research findings through conference presentations and journal publications
• Build and maintain strong relationships with local and international research network

Job Requirements:

• Possess a PhD degree in microbiology, fermentation or relevant disciplines
• Excellent knowledge and experience in microbiology and food fermentation
• At least 5 year of independent research experience and leading a research team
• Strong supervisory skills
• Strong track record for securing research funding
• Excellent publication track record
• Excellent communication and interpersonal skills, with the ability to effectively engage with diverse stakeholders at all levels
• Track record of strategic thinking capability with a outcomes-oriented mindset, able to translate vision into actionable plans and driving their execution

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 5 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 2 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub).

The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 3+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub). The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 5+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• At least a minimum of 5 years of relevant experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to identify and validate candidates that address the body’s adaptive responses to weight loss.

TaRgeted Analysis of Novel Secreted Factors for Obesity Reduction and Metabolic Health (TRANSFORM)

Description:

Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g. mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies and therapeutic strategies.

Job responsibilities:

● Conduct in vitro wet lab experiments for identified candidates (e.g. cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy etc)

● Conduct in vivo screening experiments for prioritized candidates (e.g. in preclinical models of obesity)

● Conduct end-point and mechanistic experiments (e.g. target tissue and blood collection, sample preparation etc)

● Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings

● Interact and collaborate with and assist other researchers and collaborators on related projects

● Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction

● Assist in the preparation of grant applications and grant process reports

● Present findings both orally and in written form via presentations and publication in peer-reviewed journal

● Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals

● Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in dermatology, immunology, molecular allergy and clinical immunology
• Experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Working Days & Hours: 5 days across Monday – Sunday, Up to 44 hours per week. (11am - 8pm/ 12pm - 9pm)
Location: Newton/ Chinatown

Contract: yearly renewable based on business needs and individual performance

• Conduct survey interviews via outbound calls and field visits to collect timely and reliable data
• Handle incoming hotline and mailbox enquiries to resolve respondents’ issues
• Compile, record, input survey returns and data accurately into the system
• Conduct data verification of completed survey cases to ensure accuracy and reliability of data
• Establish and maintain relationship with respondents throughout the project period
• Ensure that the given KPI are being met based on the project timeline
• Provide status report to the supervisor

Requirements:
• Strong phone and verbal communication skills along with active listening
• Experience with Key Performance Indicators (KPIs) preferred
• Excellent customer service skills

Interested candidates, please click on the following link to begin your job search journey and submit your curriculum vitae (CV) directly through the official PERSOLKELLY job application platform - GO. https://go.persolkelly.com/job...

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Job Description

• Develop, validate and perform bioassays and bioanalytical assays in compliance with FDA/EMA and GLP guidelines
• Refine current method in response to changing requirements of drug development
• Prepare study plan and study data of assays performed
• Analyse and present data/results
• Document work, results, analyses and findings in laboratory notebooks or study folders as appropriate according to workflow
• Draft SOPs and study reports
• Perform literature review for various drug pipelines and assays as required
• Meet project milestones with set quality
• Ensure scientific integrity of studies conducted and reports submitted

Requirements

• BSc or MSc in biomedical science, life science or equivalent
• Prior research and development experience are required
• Proficient in mammalian cell culture and aseptic techniques is a must
• Experience in ligand binding assays mainly ELISA, cell-based assays, SDS-PAGE, western blot and reporter assays is highly desirable
• Good knowledge of cell based (potency) or ligand binding assays required in drug development process
• Proficient with office software (MS office, Teams), and familiar with statistical tools (Graphpad Prism, XLSTAT or PLA)
• Knowledge of bioassays, bioanalytics and its method validation, GLP and ISO17025 is a plus
• Good written and verbal communication skills
• Superior problem solving and troubleshooting skills, attention to details
• Good interpersonal skills

Job Description

The Centre for Ageing Research and Education (CARE) is an academic research centre in Duke-NUS Medical School. Drawing on its multidisciplinary expertise and collaborations across medical, social, psychological, economic, and environmental perspectives, CARE’s research is situated in eight broad thematic areas: Population Health, Family Caregiving, Community-Based Health and Social Care Services, Productive Ageing, Falls, Ageing and the Environment, Health Communication, and Social and Psychological Aspects of Ageing.

CARE is a vibrant centre with individuals from diverse academic and personal backgrounds, and values the energy, passion, and thought leadership of promising scholars who desire to achieve health, social inclusion, and a high quality of life for older adults in Singapore. At Duke-NUS, CARE works closely with the Health Services and Systems Research (HSSR) Signature Research Programme, a centre of academic excellence for research and education on the organisation, funding and delivery of health services, and a focus is on public health and clinical service innovation in an increasingly complex and connected world.

We are seeking a full-time Research Assistant to join the team. The selected candidate will work across research projects, with the primary responsibilities including but not limited to the following:

• Perform data management including data cleaning, quality and consistency checks, and preparation of codebooks.
• Work with other researchers on interpreting and analysing quantitative data.
• Contribute to preparation of reports, policy and research briefs, presentations, and research papers.
• Conduct follow-up assessments of study participants over the phone.
• Support other project management tasks.
• Assist with other initiatives at CARE where required.

Job Requirements

• Bachelor’s Degree in Sociology, Epidemiology, Gerontology, Public Health, Psychology, Social Work, or other related disciplines.
• Prior work experience in quantitative data analysis will be advantageous.
• Possess strong communication and interpersonal skills.
• Able to take initiatives to learn on the job and manage assigned tasks.
• Motivated and detail-oriented with the ability to work independently as well as with others in a multi-disciplinary setting.

Candidates with relevant work experience may be considered for a Research Assistant (Senior) position.

Please attach a cover letter and a CV, with names and contact information of 3 referees. Applications will be reviewed on a rolling basis. We regret that only shortlisted applicants will be notified.

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.

Job Description:

We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher’s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.

The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology or related field
• Atleast 2 years of relevant experience in immunology or related field. No virology experience necessary.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Familiar with bioinformatics
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.

Job Description:

We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher’s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.

The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology or related field
• At least 4 years of relevant experience in immunology or related field. No virology experience necessary.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Familiar with bioinformatics
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking a Laboratory Officer/ Technician (BSL-3 operations) to join us. The Laboratory Officer/ Technician will engage in day-to-day operations, housekeeping, maintenance of the high containment (BSL-3) and BSL-2 enhanced laboratories. This role will involve but is not limited to the following:

Job Responsibilities:

• Perform lab biohazard waste collection, sort, autoclave, and safe disposal.
• Liaise with biohazard waste contractor for scheduled disposal.
• Manage laboratory supplies, chemical and equipment inventory.
• Assist in coordination of the lab maintenance, calibration, repair of faulty and recertification of laboratory equipment.
• Coordinate with vendors and service providers to ensure timely delivery of lab supplies and stock checking.
• Track and manage personal protective equipment (PPE) inventory, perform regular checks, and replenish stock as needed.
• Maintain overall cleanliness and organization of the laboratories.
• Carry loads such as lab laundry and send for cleaning, drying and redistributing to storage cabinet.
• Perform ad-hoc duties as required to facilitate smooth and efficient operation of the lab.

Job Requirements:

• "N" Level/"O" Level/ITE/NITEC/Higher NITEC/Diploma.
• Minimum 2 years working experience in a BSL-2 laboratory setting.
• Experience in a high containment environment will be advantageous.
• Team player, proactive and possess good communication skills.
• Ability to work independently under minimal supervision.
• Wear PPE and don respirator to perform daily work.
• Knowledge of biohazard waste management and autoclaving procedures.
• Familiarity with research animal facility housekeeping.
• Attention to detail and strong organizational skills.
• Willing to learn and ability to follow strict safety protocols and guidelines

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking for a Principal Scientist to join us in our mission to be a leading centre of infectious diseases research. A*STAR IDL aims to develop a cohesive A*STAR response to drive and deliver translational infectious diseases research to better health and economic outcomes.

Job Description:

• Leads conceptual and technical integration of various research studies to provide leading edge solutions in antimicrobial resistance (AMR) research and development
• Conceptualize and create new technologies, patents and publications
• Review and manage operating budget of grants and team
• Establish collaborations, develop scientific proposals and ensure timely achievement of project milestones
• Manage a team and provide scientific and career mentorship to researchers and students

Job Requirements:

• PhD in Biomedical Sciences, Life Sciences, Microbiology, Molecular Biology, Infectious Diseases, Immunology or related field as above
• 4 years of post-PhD relevant experience
• Strong background in Microbiology, Immunology, Molecular Biology, Biochemistry, Genetics and Genomics
• Strong publication record
• Highly motivated and ability to develop strong research ideas to secure grant and funding
• Strong analytical, technical and problem-solving skills
• Team player with good interpersonal skills
• Good spoken and written communication skills

Tower Research Capital, a high-frequency proprietary trading firm founded in 1998, seeks a Risk Manager, with a strong background in systematic/algorithmic trading to join the global Risk and Trading Supervision team in Singapore.

Responsibilities

• Providing risk oversight for the APAC trading activities of the firm by focusing on electronic trading risk and market risk
• Support the APAC Head of Risk in developing and enhancing risk management framework, policies and procedures
• Controlling both electronic trading risk and market risk of strategies in real-time, and consequently escalating, reporting, and resolving any risk related issues in a timely manner
• Working closely with the Portfolio Managers, Traders, Core Engineering team, and Exchanges/Prime Brokers to respond effectively to any risk limit violation and resolving any trading and risk related issues
• Assisting Risk Management and Risk Technology teams to enhance the electronic trading risk controls and design the next generation of risk analytics and trading supervision systems
• Conducting ad-hoc risk analysis and back-testing on trading strategies on a regular basis

Qualifications

• Bachelor’s degree in Financial Engineering, Mathematics, Economics, Computing or related field. Quantitative Master’s degree highly regarded
• At least 5 years of experience in an electronic trading role gained from a quantitative proprietary trading group, systematic hedge fund manager, or sell-side electronic trading role
• Strong experience with algorithmic trading and low latency electronic risk controls is preferred
• Strong financial markets, products and valuation knowledge preferably in Equities, FX and related derivatives (futures and options)
• Understanding of regional exchange-specific rules and regulations
• Strong Python and database proficiency skills in conducting data and quantitative analysis
• Good track record of working with senior management, compliance, business management and technology teams
• Strong problem-solving skills, attention to details with excellent written and verbal skills
• Desire to continuously learn and proactively challenge the status quo to improve existing processes

Please apply here: https://talent.sage.hr/jobs/12fc69c2-7012-4edc-b214-bb9c2ded1da2

Applicants will need to include a Cover Letter and CV with publication list.

Applications will be reviewed on a rolling basis, with final submission 20 January 2025.

We are particularly looking for IC Design Research Engineers with the following backgrounds:

- Digital IC Design

- Analog IC Design

As an IC Design Research Engineer, you will design and innovate secure circuits and systems for next-generation low-power IoMT devices and sensors, focusing on hardware security, and smart computing and connectivity platforms.

Imperial College London and Nanyang Technological University (NTU) are seeking Research Engineers and Research Fellows to join the exciting new Imperial/NTU CYber Protection for HEalthcaRe (IN-CYPHER) research programme on the cybersecurity of connected medical devices and systems.

The successful candidates will join the research programme which represents a collaboration between the United Kingdom and Singapore and will be based at the newly established Imperial Global Singapore (IGS) housed within the unique CREATE campus.

Positions will be initially for 2 years fixed term (subject to 6-month probation) with potential for extension.

Informal enquiries are greatly welcome. You are encouraged to send an e-mail to Dr Viktor Schlegel, Deputy Programme Director [email protected], together with an indication of the specific position you would like to apply for.

Questions about the recruitment process, should go to Paige Noyce, Associate Director [email protected].

Positions are based in Singapore at Imperial Global Singapore at the National Research Foundations Campus for Research Excellence and Technological Enterprise (CREATE) located on the campus of the National University of Singapore.

Job Description

We are looking for talented wet-lab Research Fellow to work with a multidisciplinary group of scientists on the discovery of new targets for therapy in Diabetic Nephropathy (DN), a devastating complication of diabetes causing significant morbidity, mortality and human suffering. In Singapore, the incidence of DN as a cause of end-stage kidney disease is among the highest in the world. The job will be part of the NMRC-funded project called Diabetes Study in Nephropathy and other Microvascular Complications II, and it will be based within the Centre for Computational Biology (CCB). This position will be for a period of 3 years, with possible extension depending on work performance and funding availability.

The selected candidate will perform a variety of research activities, which include planning, organising and conducting research studies within the overall scope of a research project under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Contribute to occasional educational / instructional activities and project management.
• Provide guidance and mentorship to undergraduate / medical students and research assistants.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in a related scientific area (e.g., Life Sciences/Biomedical Sciences, Pharmacology). Candidates with higher credentials may be considered for Senior Research Fellow appointment.
• Hands-on experience with transgenic models (breeding and maintenance) and surgery.
• Experience with rodents (mice/rats) phenotyping, including metabolic traits, biochemistry, histology and microscopy.
• Hands-on experience with wet-lab techniques in molecular and cell biology, including familiarity with primary cell cultures and inflammatory and metabolic cellular assays.
• Possess knowledge and experience in pharmacology and pharmacokinetics.
• Have a system-level understanding of human cardiometabolic pathology.
• Proven track record in the form of peer-reviewed research publications.
• Demonstrated capability of research independence progressively.
• Possess strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will play a key role in a natural products-based drug discovery program, conducting analytical chemistry, bioassays, compound management, molecular and cell biology, and biochemistry laboratory experiments under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Support all aspects of the research project.
• Conduct extractions and fractionation of natural products.
• Execute cancer and other mammalian cell culture assays.
• Carry out antibacterial and antifungal assays and assist with microscopy imaging of cells.
• Perform molecular and phenotypic analyses to understand mechanism of action.
• Conduct accurate monitoring, documenting and reporting of experimental results and/or research findings.
• Assist with general upkeep of laboratory needs, procurement of reagents, maintain safety protocols, provide technical support and establish work procedures to ongoing research projects.
• Perform other related duties incidental to the work described therein.

Job Requirements

• Bachelor’s or Master’s Degree in Analytical Chemistry, Chemical Biology, Pharmacology, or other related fields. Candidates with higher credentials may be considered for the Research Assistant (Senior) position.
• Familiar with organic and analytical chemistry techniques, including chromatography and HPLC.
• Demonstrated knowledge and possesses experience in cell and molecular biology techniques such as cell culture, western blot, RNA and DNA isolation, and RT-qPCR.
• Strong interpersonal communication skills with excellent written, and computer skills.
• Well-organised and excellent record keeping skills are a must.
• A strong team player who is open-minded, energetic, highly motivated and can work collaboratively in an interdisciplinary team and diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Duke-NUS Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will play a key role in a natural products-based drug discovery program. He/she will work both independently and collaboratively to analyse complex natural products using NMR and mass spectrometry, including metabolomic profiling to identify potential molecular targets and mechanisms.

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Source financial support for research activities by investigating potential sources of funding, collaborate with Principal Investigator to write and revise grant/fellowship applications.
• Provide guidance and mentorship to junior researchers.
• Ensure optimal progress of experiments in the laboratory by conducting, supervising, and evaluating laboratory procedures and outcomes. Revise and analyse targets to obtain high-quality and reproducible results.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in Chemistry, Chemical Biology, or related discipline with 2 years of relevant post-doctoral experience.
• Demonstrate general expertise in the field of natural products isolation, metabolomics, and global profiling.
• Strong NMR and mass spectrometry skills in compound characterisation.
• Familiar with database and networking platforms for dereplication (e.g., GNPS).
• Proven track record in the form of high impact publications.
• Strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

Job Description

The Cardiovascular and Metabolic Disorders (CVMD) Programme at Duke-NUS houses state-of-the-art technologies for profiling mitochondrial function and metabolic adaptations in model organisms and undertakes translational research in cardiovascular and metabolic disorders. The program has a strong track record of publication in top-tier journals, successful commercialisation efforts leading to spin-offs, as well as nurturing early career researchers into independent academic or industry positions.

Metabolic dysfunction-associated steatohepatitis (MASH) is a severe metabolic liver disease that can affect up to 6.5% of the adult population, with only one FDA-approved drug. Dr. Jin Zhou’s team is specialised in studying the novel molecular pathogenesis underlying MASH for the identification of new druggable targets. The lab uses a combination of biochemistry, genetics, animal modeling, and metabolomics approaches to understand cellular processes related to mitochondrial function and hepatic lipid metabolism.

We are looking for a highly self-motivated Research Fellow to join the team. The selected candidate will perform a variety of research activities, including but not limited to the following:

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Maintain accurate and complete records of all findings and ensure the validity and reliability of data at all times.
• Present research outcomes orally, and draft research abstracts and manuscripts for publication.
• Provide guidance and mentorship to undergraduate/medical students and research assistants.
• Perform other related duties incidental to the work described herein.

Job Requirements

• PhD in Biomedical Sciences, Molecular Biology, Cell Biology, Pharmacology, or related disciplines.
• Hands-on experience with mice models, as well as wet-lab techniques in molecular and cell biology. Prior experience in polysome and/or ribosome profiling would be advantageous.
• Proven track record of academic publications, including writing/drafting first-author papers.
• Demonstrate excellent communication, technical independence, and analytical and problem-solving skills.
• Self-motivated individual, enthusiastic to take initiative, and able to work independently and collaboratively in a team.

We regret that only shortlisted candidates will be notified.

As the Research Engineer (Equipment/Operations), you are directly involved in tool installation activities for semiconductor process tools. You would need to work proactively to coordinate with the contractor on the ground for the execution and take corrective and preventive actions of lessons learned, due diligently to prevent reoccurrence. You are responsible for performing utilities turn-on after installation is completed. You must perform the activities per ASTAR site procedure and safety policies to ensure all tool-install-related activities are completed, meeting safety, quality, schedule and budget requirements. You will also be required to perform other activities such as operations for the different semiconductor modules (Diffusion, Litho, Dry/Wet Etch, Thin Film, Implant, etc).

Responsibilities:

• Coordinate with all tool-install base contractors to execute equipment hookup for new tools, to meet the high-quality standards, dynamic schedule, and forecasted budget.
• Coordinate with the Project owner (NGTC/APM) to facilitate utility release as per the planned schedule and update tool release status timely
• Follow all safety and environmental procedures to ensure compliance with EHS-related regulations, risk assessment, safe work procedures, and permit-to-work system.
• Play an active role in safety, actively participating in safety discussions and safe work practices.
• Establish regular area walks to identify opportunities for improved safety, cleanliness, housekeeping and efficiency
• Establish regular, working interaction with peers as well as vendors in tool installation & facilitation, communicating clearly and respectfully all relevant information.
• Keep the reporting officer informed regarding the progress of assigned work and any abnormalities observed in your area.
• Demonstrate ability to understand drawing and highlighting discrepancies
• Follow area-specific procedures and documentation
• Prioritize work tasks to meet schedule and expectations, minimum guidance
• Perform tool tool-relativities and cleanroom systems troubleshooting during the hookup phase
• To perform equipment trouble-shooting of the equipments in NGTC when the need arises
• To perform utility-on after installation completion and to work closely with LCAM for complete closure
• To perform tests balancing of exhaust for new tools whenever necessary
• To perform measures for tool consumption during the hookup phase and to work closely with LCAM
• Use methods to organize, calculate, and display data accurately for utility and flowrate measurement
• Perform site activities in accordance to the Discipline

Requirements:

• Degree/Diploma in Mechanical/Electrical/Chemical engineering or equivalent
• Semiconductor experience (Equipment & Process)
• Facilities field or Wafer Fab Manufacturing equipment background will be an advantage.
• AutoCAD