Essential duties and responsibilities for this position include:

• The candidate will work together with a multidisciplinary research team to develop the quantum optical characterization setups, such as g(2) measurements, entangled photon measurements
• Optical characterizations of the fabricated quantum optical & nanophotonic devices.
• Data processing, programming, and automation of characterization setups
• Scientific dissemination (journal papers, conferences, and patents)

The detailed job requirements:

• A PhD Degree in physics/quantum optical characterization
• Strong publication track record
• Strong foundation knowledge in quantum optical characterization.
• Strong capability with optical alignment and optical characterization is an essential requirement.
• Self-motivated and passionate on research work
• Possess good critical thinking and problem-solving skills
• Good team player
• Excellent oral and written communication skills
• Applicants with no minimum work experience may apply

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The successful candidate will work with Assoc Prof Quek Su Ying on excitonic properties of layered materials under a project on Materials for Room Temperature Exciton Condensates: From Database to Laboratories.

The main responsibilities of the position include:

Using an electrostatic model combined with first principles calculations to compute the excitonic properties of selected layered materials with thicker layers.

Qualifications

• Qualifications / Discipline: Physics (PhD)
• Skills: First principles calculations, modelling
• Experience: Experience with first principles calculations in layered materials

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

• Support full spectrum finance duties, including but not limited to procurement, payments, accounts receivables in line with hosting institutions and grantor guidelines
• Provide grant management administration, such as grant claims, progress report’s financial reporting and other grant variation request.
• Provide administrative support, such as assets management, filing, phone enquiries, mails collections, stationery orders, etc
• Provide finance and administrative support for Annual Scientific Meeting and assist in pre and post event activities
• Assist in other finance or administrative functions as and when required by team

Qualifications

Degree in Administration, Accounting or Finance, and minimum 2 years of work experiences

• Positive working attitude, proactive and willing to learn
• Good organization and communication skills
• Experience in SAP HANA, Ariba
• Good knowledge of Microsoft Office application like Excel, Word, Teams, DocuSign and online communication application is an added advantage

As an Equipment Engineer, you will own all assigned toolsets. The preferred candidate can troubleshoot difficult and poorly defined problems related to mechanics, electronics, and processes using tool knowledge/experience, SPC, schematics, and other available resources. The candidate will collaborate extensively with the area maintenance team and process engineering. Some collaboration will be with tool vendors, other area engineers/managers, procurement, and production.

Responsibilities:

• Provide technical leadership and management of 200MM and 300MM Semiconductor processing equipment in Support of Main Stream Semiconductor Processes and Advanced Packaging processes. Highly desirable for a candidate to have a background in at least one of the following areas: Photolithography, PVD and CVD Thin Films, Dry Etch, Wet Etch /Wafer Clean, Diffusion, Bond, Electroplate (ECD), CMP, or Metrology (some areas may be combined).
• Work with process engineering to drive root-cause corrective actions for equipment failures, implement permanent solutions, and eliminate chronic and long-term down events.
• Lead continuous improvement teams to drive tool matching, availability, and throughput improvements and reduce risk.
• Management of new tool installation, start-up, and tool upgrades to increase fab capability and capacity, lower costs, and improve yields.
• Work with minimal supervision, balancing competing priorities, to serve the needs of the Maintenance, Production, and Development organizations.
• Participate in cross-functional teams that create efficiencies across all layers of the organization.

Required Qualifications

• Degree / Diploma with 10+ years of relevant Semiconductor Industry Experience in Mechanical, Electrical, or Chemical Engineering, Materials Science, Physics, or another relevant Engineering discipline.
• 6+ years of experience within the respective areas of expertise. Experience should include one or more: Semiconductor Wafer Handling, RF Power, High Vacuum, Toxic Gas Delivery systems, Precision Optics, and Wet Chemistry.
• Demonstrated experience with the application of structured problem-solving methodology.
• Positive interpersonal skills, highly energetic and self-motivated.
• Demonstrated ability to meet requirements and deliver results.
• Ability to manage and execute multiple projects simultaneously and shift priorities to meet business needs.

Preferred Qualifications

• Diploma or Bachelor of Science/Engineering in Mechanical, Electrical or Chemical Engineering or Materials Science, Physics or other relevant Engineering discipline.
• Semiconductor Wafer Handling, RF Power, High Vacuum, Toxic Gas Delivery systems, Precision Optics, Wet Chemistry.
• Positive interpersonal skills, highly energetic and self-motivated.
• Experience with Automated Fault Detection and Classification Systems (FDC).
• Strong background with utilizing SPC.
• High level of understanding of equipment component behaviour.
• Experience Integrating Equipment Maintenance Management Software

As an Equipment Engineer, you will own all assigned toolsets. The preferred candidate can troubleshoot difficult and poorly defined problems related to mechanics, electronics, and processes using tool knowledge/experience, SPC, schematics, and other available resources. The candidate will collaborate extensively with the area maintenance team and process engineering. Some collaboration will be with tool vendors, other area engineers/managers, procurement, and production.

Responsibilities:

• Provide technical leadership and management of 200MM and 300MM Semiconductor processing equipment in Support of Main Stream Semiconductor Processes and Advanced Packaging processes. Highly desirable for a candidate to have a background in at least one of the following areas: Photolithography, PVD and CVD Thin Films, Dry Etch, Wet Etch /Wafer Clean, Diffusion, Bond, Electroplate (ECD), CMP, or Metrology (some areas may be combined).
• Work with process engineering to drive root-cause corrective actions for equipment failures, implement permanent solutions, and eliminate chronic and long-term down events.
• Lead continuous improvement teams to drive tool matching, availability, and throughput improvements and reduce risk.
• Management of new tool installation, start-up, and tool upgrades to increase fab capability and capacity, lower costs, and improve yields.
• Work with minimal supervision, balancing competing priorities, to serve the needs of the Maintenance, Production, and Development organizations.
• Participate in cross-functional teams that create efficiencies across all layers of the organization.

Required Qualifications

• Degree / Diploma with 10+ years of relevant Semiconductor Industry Experience in Mechanical, Electrical, or Chemical Engineering, Materials Science, Physics, or another relevant Engineering discipline.
• 6+ years of experience within the respective areas of expertise. Experience should include one or more: Semiconductor Wafer Handling, RF Power, High Vacuum, Toxic Gas Delivery systems, Precision Optics, and Wet Chemistry.
• Demonstrated experience with the application of structured problem-solving methodology.
• Positive interpersonal skills, highly energetic and self-motivated.
• Demonstrated ability to meet requirements and deliver results.
• Ability to manage and execute multiple projects simultaneously and shift priorities to meet business needs.

Preferred Qualifications

• Diploma or Bachelor of Science/Engineering in Mechanical, Electrical or Chemical Engineering or Materials Science, Physics or other relevant Engineering discipline.
• Semiconductor Wafer Handling, RF Power, High Vacuum, Toxic Gas Delivery systems, Precision Optics, Wet Chemistry.
• Positive interpersonal skills, highly energetic and self-motivated.
• Experience with Automated Fault Detection and Classification Systems (FDC).
• Strong background with utilizing SPC.
• High level of understanding of equipment component behaviour.
• Experience Integrating Equipment Maintenance Management Software

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The Saw Swee Hock School of Public Health (SSHSPH) at the National University of Singapore (NUS) is seeking a research fellow (RF) for the various projects on chronic disease. The successful applicant will have a strong foundation in epidemiology and quantitative methods, show good initiative in troubleshooting tasks and have excellent communication skills.

The RF will play an important role in the conduct of current research projects on diabetes epidemiology, care and outcomes. In addition, successful candidates will be expected to support the preparation of new grant proposals. The RF will also be expected to work independently, while working in a team-based setting.

Responsibilities:

• Conduct and coordinate clinical or epidemiologic research under the direction and supervision of the Principal Investigator and Collaborators, including preparing applications for ethical approval, data collection and management, and quality assurance
• Manage these research projects in a team-based, cross functional research environment, which include supervising/ mentoring junior research staff and research students
• Undertake necessary statistical analysis, including advanced modelling techniques, to interrogate the data
• Draft research reports and manuscripts for scientific sharing and publication
• Support the preparation of new grant proposals
• Attend project meetings and to participate (where necessary) in other meetings
• Ensure compliance with health, safety and ethical guidelines in all aspects of work
• Undertake any other specific roles and management functions as may be reasonably required by the Principal Investigator

Requirements:

• PhD Degree in public health, epidemiology, biostatistics, health services research, health information science or related fields.
• Proficiency in English is a must as the candidate will be required to write scientific papers for publication in international peer reviewed journals and present work undertaken to a technical audience.
• Track record of publications in international peer reviewed journals
• Proficiency in the use of statistical software (Stata and R)
• Expertise in epidemiological and statistical analysis techniques, including joint modelling for time to event analysis and Markov modelling
• Ability to work independently as well as in a team-based, cross functional research environment
• Self-motivated, independent learner and detail-oriented
• Good project management skills

Recruitment is open immediately. The grade of appointment will be accorded based on candidate’s academic qualifications and years of relevant experience.

To apply, please submit the following documents:
a. Cover letter highlighting career goals and relevant experience
b. Curriculum Vitae, containing details of two named referees

Please note that only shortlisted candidates will be contacted.

The SingHealth Duke-NUS Global Health Institute (“SDGHI”) is a platform for global health activities across the SingHealth Duke-NUS Academic Medical Centre (“AMC”). The Institute aims to address current and emerging health challenges across Asia. Working in collaboration with partners, the Institute seeks to tackle prevalent health challenges, strengthen health systems and better insulate countries from pandemics and disease threats.

The Planetary Health Initiative is SDGHI’s newest strategic initiative. Planetary health pertains to the integrated state of health of both people and the planet. It recognizes that people’s health is now greatly shaped by human-driven global environmental change, such as climate change, environmental pollution, rapid urbanisation, biodiversity loss, among others. Addressing these interlocking challenges requires concerted actions within and beyond the health sector, spanning diverse disciplines and nations.

During the Initiative’s inaugural phase, the Institute will focus on launching new educational and capacity-building activities, conducting landscape analysis of the current state of play especially at the regional level, exploring research collaborations with other planetary health-oriented groups within Singapore and beyond, and implementing policy influencing and advocacy activities – all geared towards positioning the Institute as an emerging thought leader in planetary health in Asia and beyond.

The Research Fellow will be part of the Initiative’s inaugural team and will significantly contribute to the early development of the Institute’s planetary health portfolio. The selected candidate will perform a variety of research activities which include planning, organising, and conducting research studies, including but not limited to the following:

• Independently carry out the design and execution of research projects.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research.
• Provide support for external grant/protocol development, study design, ethics review application, and other research management activities.
• Contribute to other activities of the Planetary Health Initiative related to education, capacity building, innovation, policy advocacy, etc.
• Provide guidance and mentorship to undergraduate/medical students and research assistants.
• Perform duties related to the activities of the Planetary Health Initiative (such as advocacy, policy engagement, etc.).

Job Requirements:

• PhD in relevant fields such as public health, health systems, sustainable development, social sciences, among others, AND/OR post-graduate medical degree.
• Minimum with at least 2 years’ of relevant research experience and training. MD/MBBS graduates with a relevant Master’s degree may also be considered.
• Possess advanced knowledge of specific planetary health topics/issues of interest, as well as wide familiarity about the evolving planetary health field, including principles, frameworks, issues, emerging discourse, and policy developments
• Proficiency in research design and execution, preferably in conducting mixed-methods research(both quantitative and qualitative)
• Demonstrated capability of research independence growing progressively.
• Have strong writing and critical thinking skills, as well as good communication and presentation skills, which can be demonstrated through research publications in high impact journals, commentaries and blogs, conference presentations, and speaking engagements.
• Possess strong interpersonal and relationship-building skills which are vital for engagement with partners, collaborators, funders, and other external stakeholders.
• An emerging leader, team player, and project manager who can supervise and mentor junior colleagues; prioritize, multi-task and work collaboratively in a diverse workforce; and coordinate multiple projects and activities.

We regret that only shortlisted candidates will be notified.

The SingHealth Duke-NUS Global Health Institute (“SDGHI”) is a platform for global health activities across the SingHealth Duke-NUS Academic Medical Centre (“AMC”). The Institute aims to address current and emerging health challenges across Asia. Working in collaboration with partners, the Institute seeks to tackle prevalent health challenges, strengthen health systems and better insulate countries from pandemics and disease threats.

The Global Health Systems Research Unit is a new and dynamic unit focused on elucidating health system challenges and developing solutions. It collaborates with partners in Singapore and across Asia, generating evidence that drives intervention programmes across the AMC. The unit explores innovative ways to work with data, including testing AI tools for efficient management, analysis, synthesis, and visualisation of research data.

The Research Associate will play a dual role, supporting both SDGHI’s Global Health Systems and the SingHealth Centre for Person-Centred Care (CPCC). The ideal candidate will report to the SDGHI Clinical Core and work closely with the team at CPCC to contribute to projects that improve health equity and access in Singapore and across Asia.

Key Responsibilities

• Contribute to a wide range of health systems and services research programmes, including health systems analysis, policy analysis, and evaluation of person-centric initiatives.
• Develop and validate new measures of patient-reported experience and health systems and services frameworks.
• Conduct ethnographic and qualitative research, utilising participatory approaches to health systems and services research.
• Implement advanced data tools for efficient management, analysis, synthesis, and visualisation of health systems data, ensuring accuracy.
• Assist with project management, coordinating effectively among diverse stakeholders within SingHealth Duke-NUS AMC and external partners (including overseas) to achieve project goals.
• Write research manuscripts, case studies, reports, presentations to academic audiences, funders, and other stakeholders.

Job Requirements:

• Master’s Degree in Public or Global Health, Social Sciences, or a field relevant to health systems and services research.
• Minimum 3 years of professional experience in health and social systems research.
• Demonstrated proficiency in both qualitative and quantitative research methods, with experience in ethnographic and participatory approaches. Prior experience in behavioural economics is highly advantageous.
• Possess excellent academic writing and presentation skills.
• Experience in leveraging AI tools for quantitative and qualitative data synthesis and analysis is highly advantageous.
• Possess a growth mindset and can manage multiple projects with dynamic reporting lines and multiple stakeholders.
• Embrace a decolonising mindset and the principles of equity, diversity, and inclusion.
• Available for regional travel.

We regret that only shortlisted candidates will be notified.

Job description: Research Scientist, Chemical Development: Linker-payload synthesis for Antibody Drug Conjugates (ADCs):

• Engage in groundbreaking research and development in the field of synthetic organic chemistry, peptide chemistry.
• Investigate and explore new ideas and concepts by defining experiments in order to verify proof of principle.
• Collaborate with biologists constantly to develop novel linker-payloads for next generation Antibody-Drug Conjugates
• Collaborate closely with project team members and other cross-functional groups in the organization.
• Submit and present project updates and reports in verbal and written formats.
• Write invention disclosures and possible patent applications.
• Manage and prioritize daily assignments to ensure timely completion.
• Attend and participate in scheduled planning meetings and/or status meetings.
• Manage and maintain required reagents, laboratory environment, and equipment needed to carry out assignments.
• Adhere to safety and regulatory requirements
• Transfer new products from R&D to Manufacturing.
• Responsible for sustaining products to address customer needs
• Writing SOP and work instruction according to Quality management standards and requirements.
• Other opportunities may include possible contributions to scientific literature and presentations at conferences.

Requirements

• PhD in synthetic organic chemistry with 5 years relevant experience.
• R&D experience in multi-step small molecule synthesis, peptide synthesis
• Proficient in operating analytical equipment and applying analytical chemistry principles
• Experience with new product development is a plus
• Strong understanding of instrumentation principles and troubleshooting ability.
• Strong understanding of synthetic chemistry
• Strong understanding of Analytical chemistry principles
• Record of accomplishment should be demonstrated by publications or patents
• Demonstrated organizational skills with the ability to balance multiple tasks with different priorities
• Ability to make independent decisions and possess strong initiative
• Ability to dissect problems with strong analytical and critical thinking skills
• Ability to accurately plan, define, and manage projects tasks
• Must possess excellent verbal and written communication skills.
• Capable of working with multi-disciplinary teams.

Duke-NUS embodies a strategic partnership between Duke University and National University of Singapore (NUS). It works closely with the Singapore Health Services (SingHealth) cluster which is a network of national specialty disease centres, hospitals and polyclinics, to advance medicine and improve lives through cutting-edge research and education. Together, Duke-NUS and SingHealth form an Academic Medical Centre that comprises a number of academic collaborations.

The Health Services and Systems Research (HSSR) Programme at Duke-NUS is a centre of academic excellence for research and education on the organisation, funding and delivery of health services. The programme’ s focus is on public health and clinical service innovation in an increasingly complex and connected world. The selected candidate will work in Cardiovascular Health Research Services Unit established under the CArdiovascular DiseasE National Collaborative Enterprise (CADENCE) national clinical translational programme. They will perform a variety of activities relevant to the planned economic evaluations for health interventions and assist a team of health economists.

Job Description

• Perform data cleaning, handling and analysis
• Perform economic evaluations in healthcare (cost analysis, cost-effectiveness analysis, cost-utility analysis or budget impact analysis) with guidance
• Assist in drafting research abstracts and manuscripts
• Assist in preparation of PowerPoint presentations to various stakeholders
• Conduct literature reviews to evaluate the potential value of health innovations
• Assist in preparation of evaluation reports for the health economics team
• Extract data from existing databases and published literature
• Manage projects from start to end with guidance (i.e. Develop research objectives and study design, perform data extraction and data collation, conduct data modelling, perform statistical analysis and engage and collaborate with various stakeholders)
• Support secretariat and administrative functions pertaining to the health economics team at HSSR

Job Requirements

• Bachelor’s Degree in any discipline. Master’s Degree in Public Health is preferred.
• Minimum 3 years of working experience with quantitative data
• Adept at working with data, including processing raw data to visualise trends and deciphering patterns and ability to handle large data sets
• Experience in various quantitative research methods preferred.
• Experience or training in health economics will be beneficial.
• Experience with R programming language, and a willingness to learn more applications
• Excellent verbal and written communication and interpersonal skills
• Able to work in a team, with dynamic reporting lines and multiple stakeholders
• Able to work independently with limited supervision
• Action-oriented, highly motivated and target-focused

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with experience in dermatology, immunology, molecular allergy and clinical immunology
• At least 2 years experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• 1-2 years of experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to study the metabolic regulation of immune cells during the NASH to NASH-HCC progression.

Metabolic regulation of immune dysfunction during the progression of NASH to NASH-HCC

Description:

The lack of effective treatments for non-alcoholic steatohepatitis (NASH) and NASH-associated hepatocellular carcinoma (NASH-HCC) underscores the need to understand the transition from NASH to NASH-HCC. Identifying why some NASH patients develop HCC while others do not is a significant challenge, with growing evidence indicating that immune dysregulation plays a crucial role in this progression. The interstitial space, where cells receive nutrients and signals, significantly impacts immune function, suggesting that understanding the liver"s metabolic environment could reveal how immune cells behave during NASH progression to HCC. By profiling interstitial fluid metabolism and single-cell transcriptomics, the team aims to understand the metabolic regulation of the immune landscape in NASH to NASH-HCC progression. Using a high-fat, high-fructose, and high-cholesterol dietary mouse model that mirrors human progression, the team will study the metabolic and immune changes leading to NASH-HCC. In addition, the team’s preliminary findings show immune alterations and reduced levels of the bile acid hyodeoxycholic acid (HDCA) during NASH-HCC transition. The identified candidate will also test the potential of HDCA in preventing NASH to HCC transition, and further explore HDCA"s effects on immune cells.

Job responsibilities:

• Conduct in vitro wet lab experiments (e.g. cell culture, molecular biology and assays, microscopy etc)
• Conduct in vivo animal experiments (e.g. diet/treatment regimes, body weight & composition analyses, metabolic phenotyping, blood sampling etc)
• Conduct end-point animal experiments (e.g. terminal blood collection, tissue collection and sample preparation, whole tissue/organ imaging, serum measurements etc)
• Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings
• Interact and collaborate with and assist other researchers and collaborators on related projects
• Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction
• Assist in the preparation of grant applications and grant process reports
• Present findings both orally and in written form via presentations and publication in peer-reviewed journal
• Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals
• Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 5 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 2 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Key Responsibilities:

• Provide scientific and technical expertise to lead a research team to develop capabilities in ingredient fermentation
• Develop mechanistic understanding of the microbiology of fermentation
• Develop research proposals and seek research fundings
• Disseminate research findings through conference presentations and journal publications
• Build and maintain strong relationships with local and international research network

Job Requirements:

• Possess a PhD degree in microbiology, fermentation or relevant disciplines
• Excellent knowledge and experience in microbiology and food fermentation
• At least 5 year of independent research experience and leading a research team
• Strong supervisory skills
• Strong track record for securing research funding
• Excellent publication track record
• Excellent communication and interpersonal skills, with the ability to effectively engage with diverse stakeholders at all levels
• Track record of strategic thinking capability with a outcomes-oriented mindset, able to translate vision into actionable plans and driving their execution

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 2 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 5 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub).

The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 3+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub). The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 5+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• At least a minimum of 5 years of relevant experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to identify and validate candidates that address the body’s adaptive responses to weight loss.

TaRgeted Analysis of Novel Secreted Factors for Obesity Reduction and Metabolic Health (TRANSFORM)

Description:

Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g. mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies and therapeutic strategies.

Job responsibilities:

● Conduct in vitro wet lab experiments for identified candidates (e.g. cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy etc)

● Conduct in vivo screening experiments for prioritized candidates (e.g. in preclinical models of obesity)

● Conduct end-point and mechanistic experiments (e.g. target tissue and blood collection, sample preparation etc)

● Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings

● Interact and collaborate with and assist other researchers and collaborators on related projects

● Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction

● Assist in the preparation of grant applications and grant process reports

● Present findings both orally and in written form via presentations and publication in peer-reviewed journal

● Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals

● Contribute to other program-related projects and organizations and with the general scientific community across A*STAR