The Opportunity
Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.
Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.
Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.
Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.
Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.
We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.
The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.
Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.
Esco Aster.
One World Biosolutions for One Health.
Who we’re looking for
Physical/Mental Requirements/Work Environment
· Ability to read, analyze and interpret scientific data and publications.
· Ability to author or review protocols, technical reports, and technology transfer documents.
· Ability to author or review standard operating procedures and other related documents.
· Ability to define problems, collect data, establish facts, and draw conclusions.
· Repetitive motions due to certain laboratory techniques.
· Ability to adapt and keep up with rapid changes in a fluid and dynamic environment as this is a rapidly evolving space.
The Scope
You will be part of Esco Aster’s Genetically Modified Cell Therapy (GMC) team and contribute to the company’s CDMO mission and objectives. You will carry out process development and analytical development activities in support of drug substance and product manufacturing and testing. Your work will require close collaboration with the process development scientists and manufacturing team.
Reporting to: Head of Scientific & Sales Operations
Responsibilities
· Participate in multiple projects in the area of cell and gene therapy for process development and analytical development from small to large scale.
· Perform lab work based on the project schedule and assigned tasks from supervisors in a time efficient manner.
· Perform hands-on daily laboratory work including but not limited to primary cell culture (stem cells, immune cells, tumour cells etc.), cell-based assays (cell imaging, flow cytometry assays, killing assays etc.) and other molecular assays (ELISA, metabolite analysis etc.)
· Carry out experiment data collection, record and analysis for projects per request.
· Be involved and contribute to creation of protocols and technical reports.
· Assist in lab duties and administrative work including procurement, record keeping, maintenance of lab equipment etc.
· Exercise scientific creativity and independent thought in research & process development.
· Perform tasks in accordance with applicable regulations and site safety requirements.
· Undertake tasks assigned by leaders as and when appropriate.
Requirements
· Degree in Life Sciences or related disciplines.
· Minimum 2 years work experience in a science laboratory.
· Experience with good laboratory practices (GLP) will be an advantage.
· Experience in cell culture, aseptic techniques and analytical method development will be an advantage.
· Experience in stem cell culture / immune cell culture would be preferred.
· Experienced with bioprocess scale-up would be an advantage.
· Ability to plan and perform experiments in an interdisciplinary environment independently and efficiently.
· Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
· Able to work independently, self-starter, self-motivated and task oriented.
· Excellent written and verbal communication skills.
· Strong team player, develop positive relationship with a strong set of interpersonal skills.
· During the start-up phase of the team/facility, be willing to take on expanded role to set up workflow/processes as needed.
Apply now by submitting a Cover Letter and CV to [email protected].
