Job Description:

• Minimum 8 years of architectural experience with recognised Diploma in relevant field, and at least 5 years of experience in construction supervision for projects of similar scale and complexity in local context.

• Work as Resident Technical Officer to our LTA projects, to assist and report to RE and SRE to monitor all site activities, and any incident, including near-misses. Report any non-compliance to RE and Qualified Person Supervision (QPS).

• Assist Engineer in carrying out supervision for related works include but not limited to replacement and extension, construction and reconfiguration of viaduct/ bridge works, and associated civil works, proposed new flexible pavement and infrastructure, re-alignment of roadways, fencing and construction.

• Prepare daily reports at regular basic and as required by clients.

• Supervise all construction activities and ensure compliance to all plans/drawings, risk assessment and specifications.

• Willing to work on rotation shifts.

• Ensure compliance to all health and safety policies.

• Ensure that contractor and their subcontractor comply with client's safety requirement, and safety checklists are follow.

• Reject poor quality of works at site and inform RE to raise non-conformance notice.

• Assist RE to manage and maintain records and documentation on field or site changes and to monitor adherence to construction schedule.

• Carry out standing supervision for critical site activities based.

• Preferably PR and Singaporean.

The Centre for Ageing Research and Education (CARE) is an academic research centre in Duke-NUS Medical School. Drawing on its multidisciplinary expertise and collaborations across medical, social, psychological, economic, and environmental perspectives, CARE’s research is situated in eight broad thematic areas: Population Health, Family Caregiving, Community-Based Health and Social Care Services, Productive Ageing, Falls, Ageing and the Environment, Health Communication, and Social and Psychological Aspects of Ageing.

CARE is a vibrant centre with individuals from diverse academic and personal backgrounds, and values the energy, passion, and thought leadership of promising scholars who desire to achieve health, social inclusion, and a high quality of life for older adults in Singapore. At Duke-NUS, CARE works closely with the Health Services and Systems Research (HSSR) Signature Research Programme, a centre of academic excellence for research and education on the organisation, funding and delivery of health services, and a focus is on public health and clinical service innovation in an increasingly complex and connected world.

We are seeking a full-time Research Assistant to join the team. The selected candidate will work across research projects, with the primary responsibilities including but not limited to the following:

• Perform data management including data cleaning, quality and consistency checks,and preparation of codebooks.
• Workwith other researchers on interpreting and analysing quantitative data.
• Contribute to preparation of reports, policy and research briefs, presentations, and research papers.
• Conduct follow-up assessments of study participants over the phone.
• Support other project management tasks.
• Assist with other initiatives at CARE where required.

Job Requirements

• Bachelor’s Degree in Sociology, Epidemiology, Gerontology, Public Health, Psychology,Social Work, or other related disciplines.
• Prior work experience in quantitative data analysis will be advantageous.
• Possess strong communication and interpersonal skills.
• Able to take initiatives to learn on the job and manage assigned tasks.
• Motivated and detail-oriented with the ability to work independently as well as with others in a multi-disciplinary setting.
• Candidates with relevant work experience may be considered for a Research Assistant(Senior) position.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The National University of Singapore invites applications for Research Assistant in the Human Potential Translational Research Programme (HPTRP), Yong Loo Lin School of Medicine. The HPTRP aims to bring together researchers from a wide range of disciplines with an interest to maximise human potential. In HPTRP, focusing only on human studies, we aim to adopt a holistic perspective that considers human potential as an integrative measure of health, productivity, performance, human capital and overall well-being over the lifespan, in our environment. Appointments will be made on one-year contract, with the possibility of one-year extension.

Purpose of the post

The Research Assistant will work closely with the IHDP’s Biobank Team. The RA’s principal role will be to work in general practices of biosample transporting, processing, storage, data entry and other tasks as assigned by Reporting Officer,

Main Duties and Responsibilities

The Research Assistant/Research Associate will:

1. Process a wide range of biosamples that includes but not limited to blood and stool.
2. Provide and maintain accurate laboratory record and data
3. Adhere to all laboratory safety and procedures in accordance with the laboratory SOPs.
4. Maintain the highest standard of professional conduct and record keeping in accordance with SOPs
5. Perform laboratory housekeeping as assigned
6. Must be work at 3 sites as rostered
7. Must be able to work on weekends
8. Perform other duties as assigned by Reporting Officer

Qualifications

The applicant should:

1. have a bachelor’s degree in biomedical science, Life science or related discipline.
2. Must have laboratory experience and competent in pipetting
3. Able to work in a fast-paced environment
4. Able to work independently and in a collaborative manner with interdisciplinary team
5. Effective verbal and written communication skills
6. Strong desire to learn continuously

Remuneration will be commensurate with the candidate's qualifications and experience.

Only shortlisted candidates will be notified.

Interested parties may apply on NUS Career portal and please contact Ms H’ng, [email protected] should there be any queries pertaining to the position.

• Promoting and sales of relevant products and services
• Delivery of excellent customer service and enquiry handling
• Leads hunting and re-engaging of existings clients
• Arranging and attending to appointments of related sales activities
• Keep records of customer interaction and relevant transactions data
• Handle documentation and other administrative duties

Qualifications

• Minimum GCE “O” Level, Higher NITEC or equivalent

Requirements

• Proactive and able to work independently.
• Detail-oriented, result-driven and self-motivating
• Good verbal and interpersonal communication skills
• Basic knowledge in automotive industry and relevant car trading experience is an advantage

• Basic + Commission

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

This project aims to investigate the performance of cementitious materials and 3D printed concrete against ballistic and blast loadings. The researcher will be required to cast and fabricate the various cementitious materials and 3D printed concrete, prepare the logistics and perform the relevant ballistic and blast tests. He/she will also be required to set up the numerical models in commercial FE software (e.g. LS Dyna), validated against experimental data, to understand the mechanisms in resisting the high impact loadings for the various cementitious materials.

Job Requirements

The research fellow should have a PhD degree in a relevant field, with experience in the following areas:

• 3D concrete printing;
• Laboratory ballistic tests;
• Design of blast tests for concrete specimens;
• FE simulations of blast loading on concrete structures.

-Strong written and spoken communications and able to present results.
-Open to fixed-term contract.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

An exciting opportunity has arisen for a highly motivated Senior Research Fellow/Research Fellow to join the Centre for Holistic Initiatives (CHILD) for Learning and Development, Yong Loo Lin School of Medicine, National University of Singapore. CHILD brings together experts in the field of translational research, child health and development, and implementation science to accelerate the use of evidence in policy and practice and give every child the best start in life.

The successful candidate will support the Centre by i) conducting research projects aligned to the Centre’s strategy and key priorities, ii) preparing reports, publications and materials for funding bids, iii) providing supervision and mentorship to junior researchers, particularly in the area of mixed methods research, and iv) facilitating workshops and engagement activities.

Job Responsibilities

The successful candidate will:

• Work closely with the team leads, cross-disciplinary research teams and collaborators.
• Design, plan, undertake and deliver research and evaluation projects using both quantitative and qualitative designs.
• Provide expert methodological and statistical advice to Centre staff across Centre projects.
• Provide advanced statistical analyses and data visualizations using R, Python, or STATA for presentation of important findings in policy briefings and peer-reviewed publications
• Lead writing for reports, peer-reviewed publications, and grant proposals
• Contribute and lead, where appropriate, research dissemination activities at internal and external meetings and conferences.
• Provide supervision and mentorship of research students, assistants, and interns
• Work closely with stakeholders from across the early childhood sector.
• Carry out administrative duties as needed
• Any other duties as assigned by the supervisor

Qualifications

A PhD in Psychology/Behavioral Science/Developmental Psychology/Education/Public Health or a related discipline.

Experience: Candidates with experience in the following areas are encouraged to apply:

• Mixed methods applied research
• Multivariate statistical analyses and meta-analysis techniques using R, Python, or STATA
• Behavioural or Social Sciences applied to child health/development
• Implementation Science
• Programme Evaluation
• Education/Health Services or Applied Research

Skills

The candidate should also possess:

• Experience undertaking or leading independent research studies, as appropriate for career stage
• A strong grounding in mixed methods and applied educational, behavioural or health research – broadly defined
• Outstanding data analysis and visualization background
• Ability to search, summarize, and synthesize previous research in areas of interest to CHILD
• Strong project management and coordination skills, with attention to detail and critical thinking abilities
• Track record of publishing in peer-reviewed journals and presentations in international or national scientific conferences, commensurate with career stage
• Excellent command of spoken and written English with excellent communication skills to present findings to English-speaking stakeholders
• A team player with an ability to work independently
• Highly motivated, proactive, and goal-oriented
• Keen interest in the area of early child development and passion for research translation and communication

Application

Please submit your application, supported by:

• a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations)
• a cover letter introducing yourself, career goals and earliest start date as well as your suitability and interest in the position
• a writing sample that reflects your analytic skills and communication abilities.
• full contacts of three (3) referees to this job portal

The appointment title and salary grade commensurate with the candidate qualifications and experience. Interested applicants are invited to submit via the NUS career portal. Applicants can email [email protected] with any questions. Only shortlisted candidates will be contacted.

About CHILD

What Being Successful in the Role Looks Like The successful candidate will work closely, collaboratively, and competently as part of an interdisciplinary team within CHILD. They will have excellent writing, presentation, and project management skills. They can perform data analysis/data visualization, willingly learn from and share knowledge with others. He/she fits into, supports, and builds CHILD’s open and positive work culture.

About CHILD: The Centre for Holistic Initiatives for Learning and Development or CHILD was established under the umbrella of the NUS Yong Loo Lin School of Medicine (NUS Medicine) with the Lien Foundation. In collaboration with partners - the Centre for Evidence and Implementation (CEI) and A*STAR’s Institute for Human Development and Potential (A*STAR IHDP), CHILD brings together experts in the field of translational research, child development, and implementation science to help give children the best start to life.

Roles & Responsibilities

Scope :

All finance and accounting matters relating to our business.

Accountabilities/Responsibilities :

-Maintaining accurate and up-to-date records of financial transactions, including accounts payable and receivable, general ledger entries, and bank reconciliations.

-To prepare invoices for reporting.

-Preparing all Final Disbursement Accounts (FDA) accurately and within deadlines.

-Prepare and arrange 'Cash To Master (CTM)' with vendors.

-Process payment to suppliers and staff reimbursement.

-Prepare monthly AP journals, postings and schedules.

-Any other adhoc tasks as assigned by your immediate supervisor

Skills and Qualifications :

Proficient in Microsoft Excel and D365

Numerical Skills and attention to details

Diploma in Accountancy or its equivalent

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The Coastal Protection and Flood Resilience Institute (CFI) Singapore at the National University of Singapore is hiring a Research Fellow (RF). The successful candidate will conduct research and technology scan on current and future trends in coastal protection and flood management solutions, including increasing use of AI in computational fluid dynamics, extreme event prediction and condition monitoring. He/she will also conduct research in some of the abovementioned topics and write research proposals to secure grants for CFI.

Job Requirements

• Possess a recognised PhD degree in civil engineering, mechanical engineering, computer science, or a related discipline
• R&D experience in coastal/offshore/structural engineering and/or AI and machine learning.
• Strong writing and communication skills.
• Ability to work independently and in a team .
• Open to fixed-term contract.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The successful candidate will work with Dr Brandon I Morinaka on production and biological evaluation of peptide natural products under a project on Genome mining and biosynthesis of peptide natural products.

The main responsibilities of the position include:
• Support safe operations and maintenance of equipment in the lab.
• Facilitate working with undergrad students when necessary.
• Assist with procurement and ordering of chemicals and consumables.
• Carry out research for new peptide natural products discovery and development including recombinant protein expression, and production and extraction of natural products.

Qualifications

• Qualifications / Discipline:
B.S. in Pharmaceutical Science, Chemistry, Biochemistry, or related discipline.

• Skills:
Biochemical techniques (protein expression and purification, SDS-PAGE, size exclusion and affinity chromatography) and/or Analytical chemistry (NMR, MS, HPLC). Good written and oral communication skills. Able to work effectively in a team.

• Experience:
Previous research experience in a chemistry, biochemistry, or biology lab.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with experience in dermatology, immunology, molecular allergy and clinical immunology
• At least 2 years experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• 1-2 years of experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to study the metabolic regulation of immune cells during the NASH to NASH-HCC progression.

Metabolic regulation of immune dysfunction during the progression of NASH to NASH-HCC

Description:

The lack of effective treatments for non-alcoholic steatohepatitis (NASH) and NASH-associated hepatocellular carcinoma (NASH-HCC) underscores the need to understand the transition from NASH to NASH-HCC. Identifying why some NASH patients develop HCC while others do not is a significant challenge, with growing evidence indicating that immune dysregulation plays a crucial role in this progression. The interstitial space, where cells receive nutrients and signals, significantly impacts immune function, suggesting that understanding the liver"s metabolic environment could reveal how immune cells behave during NASH progression to HCC. By profiling interstitial fluid metabolism and single-cell transcriptomics, the team aims to understand the metabolic regulation of the immune landscape in NASH to NASH-HCC progression. Using a high-fat, high-fructose, and high-cholesterol dietary mouse model that mirrors human progression, the team will study the metabolic and immune changes leading to NASH-HCC. In addition, the team’s preliminary findings show immune alterations and reduced levels of the bile acid hyodeoxycholic acid (HDCA) during NASH-HCC transition. The identified candidate will also test the potential of HDCA in preventing NASH to HCC transition, and further explore HDCA"s effects on immune cells.

Job responsibilities:

• Conduct in vitro wet lab experiments (e.g. cell culture, molecular biology and assays, microscopy etc)
• Conduct in vivo animal experiments (e.g. diet/treatment regimes, body weight & composition analyses, metabolic phenotyping, blood sampling etc)
• Conduct end-point animal experiments (e.g. terminal blood collection, tissue collection and sample preparation, whole tissue/organ imaging, serum measurements etc)
• Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings
• Interact and collaborate with and assist other researchers and collaborators on related projects
• Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction
• Assist in the preparation of grant applications and grant process reports
• Present findings both orally and in written form via presentations and publication in peer-reviewed journal
• Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals
• Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

Research Associate - Genomic safe harbour targeted engineering of cells for gene and cell therapy

Location: Cardiovascular-Metabolic Disease TRP, NUS YLL School of Medicine

Description:

We are looking for a Research Associate to drive the wet lab research activities for the duration of the project.

Responsibilities:

• Clone and amplify complex constructs necessary for engineering of mammalian cells
• Maintain cultures of mammalian cells to a high standard and conduct engineering experiments working closely with the project leads
• Compile and organise experimental data, including cell culture records, characterization results, and cell line inventory information
• Conduct daily wet-lab experiments e.g. nucleic acid extraction and quantification
• Assist the team to ensure a safe and efficient working environment
• Ensure project deliverables are met in a timely manner and to the highest standard

Qualifications

• Master’s Degree in Biology, Biochemistry, Molecular Biology, or related discipline.
• Minimum 3 years of working experience in a research laboratory
• Experience with mammalian cell culture and genome engineering
• Extensive knowledge of molecular cloning techniques
• Good organizational skills and ability to multitask
• Able to work independently and as part of a team
• Experience in working with lentiviral vectors is highly desirable
• Good communication (verbal and written)

This position offers an exciting opportunity to contribute to groundbreaking research in genome engineering for gene and cell therapy, with potential for career development and growth within our dynamic research environment.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

A Research Assistant position is available NUS Yong Loo Lin School of Medicine, National University of Singapore. The job entails work in a laboratory, clinical and involves administrative duties.

Major Duties and Responsibilities:

1. Contribute to DSRB/IRB application process, support ethics and regulatory related administrative work including DSRB/IRB and HSA applications
2. Coordinate training requirements and documentation
3. Ensure study file set up, documentation and maintenance, including investigator files and logs
4. Conduct subject pre-screening, assist with informed consent, adverse event reporting, and follow-up activities with regulatory bodies
5. Coordinate subject visits and manage study execution, including collection of study questionnaires, measurement of physiology parameters, and collection of non-invasive images
6. Maintain study database.
7. Monitor studies ensuring compliance with institutional guidelines, HBRA, and GCP.
8. Assist with study closure including archiving of study records (medical records, study documents, investigator files, subject files etc.), post-study audits/ inspections and monitoring.
9. Participate and present updates in study related meetings.
10. Take minutes of meetings for vetting.
11. Generate study progress reports as required.

Roles and Responsibilities

• Assist with participant recruitment for research studies, including consent taking, filing and ensuring studies are conducted in compliance with necessary regulatory guidelines
• Purchasing products and services where necessary, including preparing recommendation reports, track orders and ensure timely delivery, and keeping records of purchases.
• Assist overall day-to-day administrative activities for Research Programme
• Assist Admin Lead with CVD TRP website maintenance and update.
• Assist to prepare and edit reports, presentations and other documents.
• Assist Admin Lead with secretariat functions to arrange and coordinate Programme’s events or meetings, including creating and distribution of meeting minutes, preparing facilities for scheduled meetings and arranging refreshments, if required.

Qualifications

• Bachelor in a related discipline in the Biomedical/Life Sciences with a minimum 1 year of experience
• GCP-trained and familiar with the regulatory landscape in Singapore
• Some experience working in/with a clinical research or healthcare industry
• Sound written and verbal communications skills
• Possess maturity and good interpersonal skills
• Independent and good team player
• Self-driven, meticulous, and organized and strong organisational skills
• Relevant experience with managing large projects, lead facilitation of group meetings and managing budgets will be an advantage
• Good proficiency in MS Office applications such as PowerPoint, Excel
• Have a strong interest to interact with a wide variety of people

We are looking for a qualified individual to be involved in the below project. The candidate will work with a dynamic team to identify and validate candidates that address the body’s adaptive responses to weight loss.

TaRgeted Analysis of Novel Secreted Factors for Obesity Reduction and Metabolic Health (TRANSFORM)

Description:

Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g. mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies and therapeutic strategies.

Job responsibilities:

● Conduct in vitro wet lab experiments for identified candidates (e.g. cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy etc)

● Conduct in vivo screening experiments for prioritized candidates (e.g. in preclinical models of obesity)

● Conduct end-point and mechanistic experiments (e.g. target tissue and blood collection, sample preparation etc)

● Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results and research findings

● Interact and collaborate with and assist other researchers and collaborators on related projects

● Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction

● Assist in the preparation of grant applications and grant process reports

● Present findings both orally and in written form via presentations and publication in peer-reviewed journal

● Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals

● Contribute to other program-related projects and organizations and with the general scientific community across A*STAR

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub).

The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 3+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

The Digital Health Accelerator (DHA) is led by A*STAR, Ministry of Health (MOH) Singapore, SingHealth, National Healthcare Group (NHG), and National University Health System (NUHS). DHA supports innovators in driving adoption and scaling of market ready or near-market ready digital health solutions. DHA is hosted by Singapore's Diagnostics Development Hub (DxD Hub). The DHA integration engineer is responsible for planning and developing workflow and technical interfaces between healthcare IT systems. She/He will work with DHA Project Managers, Solution Architects, health systems and companies to accomplish this objective. She/He may also be called upon to advise other developers on integration standards.

Responsibilities:

• You’ll be involved in the development, design, build, testing, and go live phases of multiple integration projects.
• This includes scripting to conform / transform to another systems specifications.
• You will also work with internal teams to continuously improve processes and procedures around deployment of interoperability products that communicate in HIT standards-based formats such as HL7, IHE Profiles, Direct, or SMART on FHIR.
• The Integration Engineer oversees the development of new interfaces and maintain the sandbox environment up to date for application testing.

Requirements:

• Bachelor’s degree in information systems, Computer Science, Engineering, Computer Information Systems, Management Information Systems, or equivalent experience
• 5+ years’ experience in HCIT integration using established and contemporary interoperability standards (e.g. HL7, SMRT, FHIR)
• Experience with SQL and relational databases, and communication using secure protocols.
• Ability to work in a team environment alongside developers and deployment teams.
• Utilise engines like Mirth Connect or Rhapsody to have a standard way of integration using both HL7 and DICOM
• Knowledge in developing and configuring Context Launch requirements according to AES 256 standards.
• Assess and customise integrations (HL7 / FHIR / DICOM) based on the project to specific workflow.
• Experience with cloud deployments and/or pipelines, especially Pivotal Cloud Foundry
• Experience with popular healthcare integration engines with ability to recommend and/or select different integration approaches depending on the desired outcomes for the system.
• Strong communication skills and ability to work with project stakeholders from different backgrounds (e.g. technical, clinical)
• Experience integrating with Singapore public hospital technical stack and working with Synapxe are a plus.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Requirements:

• At least a minimum of 5 years of relevant experience in IOS/Android App development.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Flutter, React, Dart and native programming language.
• Proven experience in building mobile applications for Android and iOS.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Key Responsibilities:

• Provide scientific and technical expertise to lead a research team to develop capabilities in ingredient fermentation
• Develop mechanistic understanding of the microbiology of fermentation
• Develop research proposals and seek research fundings
• Disseminate research findings through conference presentations and journal publications
• Build and maintain strong relationships with local and international research network

Job Requirements:

• Possess a PhD degree in microbiology, fermentation or relevant disciplines
• Excellent knowledge and experience in microbiology and food fermentation
• At least 5 year of independent research experience and leading a research team
• Strong supervisory skills
• Strong track record for securing research funding
• Excellent publication track record
• Excellent communication and interpersonal skills, with the ability to effectively engage with diverse stakeholders at all levels
• Track record of strategic thinking capability with a outcomes-oriented mindset, able to translate vision into actionable plans and driving their execution

We are seeking a passionate and skilled Flutter Developer to join our dynamic team. The ideal candidate will have a strong understanding of Flutter development, be proficient in Dart programming, and have experience building high-quality, scalable mobile applications.

Job Responsibilities:

• Design and develop high-quality, scalable, and maintainable mobile applications using Flutter.
• Collaborate with cross-functional teams to define, design, and ship new features.
• Ensure the performance, quality, and responsiveness of applications.
• Identify and correct bottlenecks and fix bugs.
• Help maintain code quality, organization, and automatization.
• Stay up-to-date with the latest trends and technologies in mobile development.

Job Requirements:

• At least 2 years relevant experience in Flutter development. Candidates with no experience and possess relevant technical knowledge may apply.
• Bachelors degree in Computer Science, Information Technology, or a related field.
• Strong knowledge of Dart programming language.
• Proven experience in building mobile applications for Android and iOS using Flutter.
• Understanding of the full mobile development life cycle.
• Familiarity with RESTful APIs to connect mobile applications to back-end services.
• Strong understanding of design principles and user interface guidelines.
• Excellent problem-solving skills and ability to work in a team environment.
• Good communication and interpersonal skills.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

• Support procurement process at DxD Hub, ensuring technical and policy compliance as well as value-for-money.
• Structuring requirements for procurement process: Translate purchase requests from technical team to online procurement systems.
• Perform and/or support activities throughout procurement process. Example activities include creating internal approval memos and justification, preparing external documents (e.g. Invitation to Quote, Tenders).
• Support proposal evaluation: work with users to perform structured assessment of vendor proposals and recommend proposal to award.
• Partner with executives in other functions including Procurement and Finance to ensure efficient operations.
• Collate and track data to support analysis, including maintaining databases and hard copy records.
• Ensure that database is updated in a timely and accurate manner.
• Provide general administrative and clerical support to DxD Hub Team ensuring safe and comfortable DxD Hub operations.
• General administrative and clerical support to DxD Hub Team.
• Manage and monitor inventory of office and pantry supplies and re-order as needed.
• Track non-scientific equipment and assets (e.g. video conferencing system, furniture) and work with vendors for maintenance.
• Monitor facilities vendors (e.g. cleaning, telecom) to ensure a comfortable office environment for staff including light clean-up as needed.
• Work closely with SpIA and HR for the issuance of staff card for new hires and ensure that the staff has access to all DxD office sites.

Job Requirements:

• Diploma holder with a certificate in professional secretarial skills/ finance.
• Minimum 5 years of relevant experience in similar capacity.
• Experience in purchasing of biomedical consumables and equipment would be an advantage.
• Proficient in MS Office Applications, including Word, Excel, PowerPoint, and Outlook.
• A team player with excellent interpersonal, communication and organisational skills.
• Able to communicate effectively, multi-task, and work in a dynamic environment.
• Well organised and good written communication skills.
• Awareness of workplace health and safety would be an advantage.
• Meticulous and able to work independently in a fast-paced environment.
• Individual who is self-motivated, and results driven.
• Proactive and takes ownership of projects.
• Adaptable and able to work under pressure.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.

Job Description:

We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher’s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.

The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology or related field
• Atleast 2 years of relevant experience in immunology or related field. No virology experience necessary.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Familiar with bioinformatics
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.

Job Description:

We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher’s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.

The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology or related field
• At least 4 years of relevant experience in immunology or related field. No virology experience necessary.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Familiar with bioinformatics
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.