Total 114 lab technician job vacancies in d19 serangoon garden hougang sengkang punggol

The “Cellular Basis of Neural Diseases” laboratory in the Institute of Molecular and Cell Biology, A*STAR invites applications for a position as Senior Scientist I (Postdoctoral Research Fellow) in Cellular and Metabolic Therapies for Neurological Diseases.

The goal of the program is to derive clinically relevant neural cell types from induced pluripotent stem cells for development of novel therapies. This will be achieved through enhanced biological understanding of the disease progression and identification of new disease targets.

Interested candidates should have a PhD degree in Biomedical Sciences, Neuroscience, Stem Cells and Regenerative Biology or a relevant field. The ideal candidate should possess the following characteristics:

• Passionate and committed to advance the frontiers of Stem Cell/Neuroscience research
• Excellent communication skills (both written and oral)
• A team player who can perform well with colleagues as well as independently
• Proven track record of scientific research evidenced by strong publication record
• Experience with neural organoid cultures, as well as single cell RNA-seq analyses would be highly desirable
• Meticulous and organized

JOB DESCRIPTION

• Responsibilities: mouse colony management, genotyping, mouse surgery, immunostaining, tissue sectioning and staining, and other technical support requested by lab members
• Provide technical support for research

JOB REQUIREMENT

• Bachelor in Biological Science and Life Science disciplines or equivalent
• Experience with animal work will be valued
• Excellent organizational and interpersonal skills
• Highly motivated, passion for science, committed to laboratory work and able to work flexible hours
• Ability to multitask, work independently and also as part of a team
  Excellent communication (verbal and written) and presentation skills

Job Description and Requirements

A postdoctoral senior/ research fellow (scientist) position is available in Tan Yee Joo’s lab to work on hepatitis B virus. Candidate is required to work closely with fellow lab members and collaborators in a joint grant.

Requirements:

• PhD in Biomedical Science or related fields
• Highly experienced in common biochemical techniques including PCR, real-time PCR, Western blot and immunofluorescence assays
• Highly experienced in mammalian cell culture methodologies including gene knockout/knockdown, transient and stable transfections
• Experienced in virology is preferred
• Experienced in performing pathway analysis of datasets from proteomics and transcriptomics experiments is preferred
• Experienced in chromatin immunoprecipitation assay is preferred
• Have a strong publication record in peer-reviewed journals
• Be able to work in a team and conduct independent research with excellent analytical, technical and problem-solving skills

Job Description and Requirements

A postdoctoral senior/ research fellow (scientist) position is available in Tan Yee Joo’s lab to work on hepatitis B virus. Candidate is required to work closely with fellow lab members and collaborators in a joint grant.

Requirements:

• PhD in Biomedical Science or related fields
• Highly experienced in common biochemical techniques including PCR, real-time PCR, Western blot and immunofluorescence assays
• Highly experienced in mammalian cell culture methodologies including gene knockout/knockdown, transient and stable transfections
• Experienced in virology is preferred
• Experienced in performing pathway analysis of datasets from proteomics and transcriptomics experiments is preferred
• Experienced in chromatin immunoprecipitation assay is preferred
• Have a strong publication record in peer-reviewed journals
• Be able to work in a team and conduct independent research with excellent analytical, technical and problem-solving skills

A*STAR Infectious Diseases Labs (A*STAR ID Labs) is seeking for a Research Officer to join us in our mission to be a leading centre of infectious diseases research. A*STAR ID Labs aims to develop a cohesive A*STAR response to drive and deliver translational infectious diseases research to better health and economic outcomes.

The candidate will be joining the Antimicrobial Chemical Biology Lab, a newly established group in A*STAR ID Labs focusing on the development of synthetic antimicrobial compounds for potential therapeutic applications. Scholarship opportunities will be available for those interested in pursuing further education at the master’s or PhD level.

Research projects will encompass various tasks such as:

• Chemical synthesis
• In vitro activity testing
• Understanding mechanisms of action
• In vivo efficacy evaluation.
• Support the team in lab operation
• Upkeep of consumables
• Safety oversight
• Labware procurement
• Documenting experimental procedures and results.

Job Requirements:

• Bachelor’s degree in microbiology, biomedical science, chemistry, chemical engineering, bioengineering, or related field
• Familiarity with basic microbiology (e.g., bacteria/fungi culture, agar plating, PCR) and chemistry (e.g., reaction setup, column purification, HPLC) lab techniques, programming, and/or common graphics software (e.g., Photoshop) will be advantageous.
• Highly motivated and passionate about scientific research
• Good spoken and written communication skills
• Team player
• Receptive and detail-orientated

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description:

Be part of an exciting team working on cutting-edge advanced packaging process technologies. Participate in process development and integration solution to enable advanced packaging process technologies in the world of mobile, IoT, consumer and high-performance computing area. Partner and work with various teams from inside and outside of IME to help develop leading-edge packaging solutions for our customers, taking the solutions from concept to mass production. Responsibilities will include assisting in operations support in clean room to make sure projects are completed successfully and delivered on time.

This position is based in Singapore.

Responsibilities:

• Operate semiconductor equipment to perform processes, measurement, and inspection of wafers. (Include equipment setup, loading and unloading of wafers)
• Monitor basic equipment/process errors and perform recovery.
• Work with internal and external parties to align for tool time, execute process sequence and collect data to feedback to integration owner.
• Logistically transport wafer lots between equipment within cleanroom and between worksites.
• Identify and address potential areas for improvements such as cycle time, utilization, and cost.
• Perform chemical change/ top-up for equipment under supervision.
• Understand and follow all Environmental, Health and Safety (EHS) procedures and requirements.
• The candidate may be required to perform shift work (Mon-Fri).

Experience:

• NITEC/ Diploma in Electrical/Mechanical/Chemical Engineering
• Basic understanding on semiconductor process is preferred
• 1-3 years of experience in semiconductor processes (Litho, Etch, CVD, PVD, Plating, Metrology etc.) will be added advantages

Job Description:

Be part of an exciting team working on cutting-edge advanced packaging process technologies. Participate in process development and integration solution to enable advanced packaging process technologies in the world of mobile, IoT, consumer and high-performance computing area. Partner and work with various teams from inside and outside of IME to help develop leading-edge packaging solutions for our customers, taking the solutions from concept to mass production. Responsibilities will include assisting in operations support in clean room to make sure projects are completed successfully and delivered on time.

This position is based in Singapore.

Responsibilities:

• Operate semiconductor equipment to perform processes, measurement, and inspection of wafers. (Include equipment setup, loading and unloading of wafers)
• Monitor basic equipment/process errors and perform recovery.
• Work with internal and external parties to align for tool time, execute process sequence and collect data to feedback to integration owner.
• Logistically transport wafer lots between equipment within cleanroom and between worksites.
• Identify and address potential areas for improvements such as cycle time, utilization, and cost.
• Perform chemical change/ top-up for equipment under supervision.
• Understand and follow all Environmental, Health and Safety (EHS) procedures and requirements.
• The candidate may be required to perform shift work (Mon-Fri).

Experience:

• NITEC/ Diploma in Electrical/Mechanical/Chemical Engineering
• Basic understanding on semiconductor process is preferred
• 1-3 years of experience in semiconductor processes (Litho, Etch, CVD, PVD, Plating, Metrology etc.) will be added advantages

We are seeking to recruit a highly motivated Research Fellow/Research Scientist to support the institute’s overall Research and Innovation goals.

Job Description:

The Research Fellow/Research Scientist will be responsible for engineering novel CAR-NK cells with superior anti-tumor efficacy, enhanced tumor infiltration, and excellent resilience against the suppression by the tumor microenvironment.

Job Requirement:

• PhD in Immunology or Cell Biology
• Possess at least a minimum of 5 years relevant work experience
• Substantial background and publication records in cancer immunology, particularly on T and NK cells
• Experience working with patient-derived samples and experimental models
• Good organisational, verbal and interpersonal skills
• Exhibit ability in mentoring and leading the project

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A Research Officer position is available in Dr. Anand Andiappan Lab at the Singapore Immunology Network (SIgN). The RO position is to support the research work of the team that focuses on studying the role of immune system in eczema and allergies. The candidate will work on primary cells from cohorts and cell culture systems towards understanding immune pathophysiology of disease. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by confocal microscopy, and associated data analysis with statistical tested.

Job Duties:

• Managing safety in the lab
• Creating SOPs and lab risk assessments
• Maintaining lab inventories
• Perform other lab administrative duties and operations such as ordering and tracking lab budget
• Experience with human and mouse blood/tissue sample handling and processing (e.g. isolation of specific immune cell population) and knowledge of immune cell biology is encouraged
• Experience with flow cytometry analysis for different immune cell population and functional immune assays will be an advantage

Job Requirements:

• Degree in Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with experience in molecular biology techniques, immunology, cancer cell biology, cell culture and flow cytometry
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills
• Candidates are expected to be highly motivated to work in research and able to perform tasks independently.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are seeking to recruit a highly motivated Research Fellow/Research Scientist to support the institute’s overall Research and Innovation goals.

Job Description:

The Research Fellow/Research Scientist will be responsible for engineering novel CAR-NK cells with superior anti-tumor efficacy, enhanced tumor infiltration, and excellent resilience against the suppression by the tumor microenvironment.

Job Requirement:

• PhD in Immunology or Cell Biology
• Possess at least a minimum of 2 years relevant work experience
• Substantial background and publication records in cancer immunology, particularly on T and NK cells
• Experience working with patient-derived samples and experimental models
• Good organisational, verbal and interpersonal skills
• Exhibit ability in mentoring and leading the project

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A Research Officer position is available in Dr. Anand Andiappan Lab at the Singapore Immunology Network (SIgN). The RO position is to support the research work of the team that focuses on studying the role of immune system in eczema and allergies. The candidate will work on primary cells from cohorts and cell culture systems towards understanding immune pathophysiology of disease. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by confocal microscopy, and associated data analysis with statistical tested.

Job Duties:

• Managing safety in the lab
• Creating SOPs and lab risk assessments
• Maintaining lab inventories
• Perform other lab administrative duties and operations such as ordering and tracking lab budget
• Experience with human and mouse blood/tissue sample handling and processing (e.g. isolation of specific immune cell population) and knowledge of immune cell biology is encouraged
• Experience with flow cytometry analysis for different immune cell population and functional immune assays will be an advantage

Job Requirements:

• Degree in Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in molecular biology techniques, immunology, cancer cell biology, cell culture and flow cytometry
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills
• Candidates are expected to be highly motivated to work in research and able to perform tasks independently.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with at least 5 years experience in dermatology, immunology, molecular allergy and clinical immunology
• Experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Job Description & Responsibilities:

• Maintenance of Quality Management System ensuring compliance to internal, and international standards and regulatory requirements for medical devices.
• Develop QMS documents in line with business activity of DxD Hub.
• Work with technical team to create quality document related to product design, development and manufacturing, including product test/validation protocols, change management in compliance to applicable regulatory requirements.
• Develop and evaluate medical device regulatory intelligence and maximize opportunities to expedite the registration process within S.E.A region, China and USA. Activities include obtaining and maintaining domestic and regional market access for our innovative products.
• Provide appropriate inputs to assist in defining regulatory strategies and timelines for regulatory submissions for the total product lifecycle for medical devices.
• Compile technical, clinical and production protocols and documentations necessary for new products dossier submission to S.E.A. region, China and USA. regulatory submissions. Liaise with technical team (locally and internationally) on technical information required to prepare submission dossiers. Manage preparation (developing submission content, management of document legalization, and creation of any other documents required for submissions) and maintenance of regulatory submissions and other premarket registrations to acquire appropriate commercial distribution clearances in accordance with regulatory strategic plan.
• Overall responsible for ensuring that medical device files are set up in compliance to regulatory requirement.
• Monitor and communicate new and changing medical device law, guidance regulations in a timely manner. Reviews process change recommendation and assists in implementing new procedures and documentation.
• Ensure that regulatory records are controlled and maintained.
• Train internal and external stakeholders on regulatory data management processes and platforms, regulatory matters and product registration.

Job Requirements:

• Master or Bachelor of Science/Engineering with strong background in biomedical, computer or engineering sciences.
• Possess 3 years or more of working experience in quality assurance and regulatory affairs in medical devices; thorough working knowledge of ISO 13485:2016.
• Good working knowledge in managing QMS in a medical device environment in compliance to ISO 13485:2016.
• Competent in quality assurance methodologies.
• Working knowledge in QA processes for design, development and manufacturing of IVD, SaMD and Integrated Medical Technologies.
• Demonstrated skills in risk management (ISO 14971).
• Knowledge of Health Sciences Authority requirement for IVD product submission.
• Knowledge in regulatory requirements for medical devices in ASEAN, USA and EU.
• Experience with product registration submission and evaluation.
• Experience with maintaining internal regulatory database.
• Experience with Dossier Creation.
• Ability to develop and implement plans for regulatory submission.
• Awareness of applicable workplace environment, health and safety regulations.
• Ability to network and build strategic partnership with good problem solving skills and communication skills.
• Possess leadership and agile mindset.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A Research fellow position is available in Dr. Anand Andiappan Laboratory at the Singapore Immunology Network (SIgN). The successful candidate will support the research work that focuses on studying inflammaeing in the context of skin aging in Asian populations.

The candidate will work on primary cells from cohorts and cell culture systems towards understanding functional immune responses in skin immune interactions and recapitulating them in in-vitro and ex-vivo systems. Additional work involves cellular and stimulation assays with flow cytometry and FACS analysis along with imaging by microscopy, and associated data analysis with statistical tested.

Duties will include managing safety in the laboratory, creating Standard Operating Procedures (SOPs) and laboratory risk assessments, maintaining laboratory inventories, perform other laboratory administrative duties and operations such as ordering and tracking laboratory budget.

Job Requirements:

• PhD Degree in Skin Immunology, Life sciences, Biomedical sciences, Molecular Biology, Biotechnology or equivalent
• Preferably with experience in dermatology, immunology, molecular allergy and clinical immunology
• At least 2 years experience with human and mouse blood/tissue sample handling and in vitro cell culture and processing (e.g. isolation of specific immune cell populations, differentiation and activation assay)
• Experience with flow cytometry analysis for different immune cell populations and functional immune assays
• Highly motivated to work in research laboratory and able to perform tasks independently
• Precise, detailed-oriented and able to follow complex protocols
• Willing to learn new experimental procedures and troubleshoot assays
• Good team player with good interpersonal skills
• Good spoken and written communication skills

Please submit your application with a cover letter summarizing your research experience.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

We are seeking a highly motivated and dedicated team player to join our dynamic research team. Our lab focuses on advancing the field of RNA therapeutics, with a strong emphasis on translational research aimed at clinical applications, while also fostering foundational discoveries in the delivery of RNA therapeutics. Our core technology platforms include rational design of antisense oligonucleotides and the development of innovative in vitro and in vivo methods for real-time and high-throughput functional delivery of RNA therapeutics.

Key Responsibilities:

• Experimental Execution: Execute experiments to investigate the efficacy, safety, and mechanisms of RNA therapeutics in cellular and animal models. Utilize state-of-the-art techniques to achieve research goals.
• Data Analysis: Analyze experimental data, interpret results, and draw meaningful conclusions. Present findings at lab meetings, conferences, and in scientific publications.
• Collaboration: Collaborate closely with other lab members, including graduate students and faculty, to drive interdisciplinary research projects and contribute to a vibrant scientific community.
• Translational Focus: Engage in research activities that have direct implications for the clinical application of RNA therapeutics, actively participating in discussions related to translational strategies.

Qualifications:

• Degree in Science disciplines or equivalent.
• Mouse and colony management experiences are required.
• Background in RNA biology, nucleic acid therapeutics, or related areas is ideal.
• Proficiency in molecular biology techniques, cell culture, and animal models.
• Excellent communication skills, both written and oral, and the ability to work collaboratively in a team-oriented environment.

A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking a Laboratory Officer/ Technician (BSL-3 operations) to join us.

The Laboratory Officer/ Technician will engage in day-to-day operations, housekeeping, maintenance of the high containment (BSL-3) and BSL-2 enhanced laboratories. This role will involve but is not limited to the following:

Job Responsibilities:

• Perform lab biohazard waste collection, sort, autoclave, and safe disposal.
• Liaise with biohazard waste contractor for scheduled disposal.
• Manage laboratory supplies, chemical and equipment inventory.
• Assist in coordination of the lab maintenance, calibration, repair of faulty and recertification of laboratory equipment.
• Coordinate with vendors and service providers to ensure timely delivery of lab supplies and stock checking.
• Track and manage personal protective equipment (PPE) inventory, perform regular checks, and replenish stock as needed.
• Maintain overall cleanliness and organization of the laboratories.
• Able to carry loads such as lab laundry and send for cleaning, drying and redistributing to storage cabinet.
• Perform ad-hoc duties as required to facilitate smooth and efficient operation of the lab.

Job Requirements:

• "N" Level/"O" Level/ITE/NITEC/Higher NITEC/Diploma.
• Minimum 2 years working experience in a BSL-2 laboratory setting.
• Experience in a high containment environment will be advantageous.
• Team player, proactive and possess good communication skills.
• Ability to work independently under minimal supervision.
• Able to wear PPE and don respirator to perform daily work.
• Knowledge of biohazard waste management and autoclaving procedures.
• Familiarity with research animal facility housekeeping.
• Attention to detail and strong organizational skills.
• Willing to learn and ability to follow strict safety protocols and guidelines

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Host Pathogen Interactions in A*STAR Infectious Diseases Labs (A*STAR ID Labs) is seeking a Postdoctoral Researcher to join the lab.

We are seeking a talented and collaborative post-doctoral researcher to work in the broad scope of host-pathogen interactions and infectious diseases. The lab has various funded projects on the comparison of host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric and multiOmic approach. Other projects include immune response evaluation of vaccine adjuvant candidates, development of cell-based reporter systems of viral infections to facilitate and accelerate antiviral studies, as well as development of novel vaccine strategies.

The candidate will be expected to work on funded projects as well as develop novel research projects in the scope of the lab research interests to be able to apply to the various early career development schemes both at an internal and external national level. Virus studied in the lab are positive sense RNA viruses as well as some negative sense RNA viruses. Other common techniques and tools in the lab include protein-protein/RNA interactions, microscopy, functional genomics, viral reverse genetics, CRISPR Cas9 gene editing. Animals models available in the lab include mice and zebrafish.

Throughout the project, close collaborative work within A*STAR ID Labs as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.

Job Requirements

• PhD in Biomedical Sciences, Life Sciences, Immunology, Virology or related field
• At least 2 to 3 years of relevant experience (immunology or related field) is a plus.
• No virology experience necessary. Prior bioinformatic experience is a plus.
• Highly motivated and able to work independently.
• Team player with good interpersonal skills.
• Good spoken and written communication skills.
• Willing to learn to work in a BSL3 facility if necessary
• Must be comfortable to work with small animal models.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A*STAR Infectious Diseases Labs (A*STAR ID Labs) is seeking for a Scientist to join us in our mission to be a leading centre of infectious diseases research. A*STAR ID Labs aims to develop a cohesive A*STAR response to drive and deliver translational infectious diseases research to better health and economic outcomes.

The candidate will be joining the Antimicrobial Chemical Biology Lab, a newly established group in A*STAR ID Labs focusing on the development of synthetic antimicrobial compounds for potential therapeutic application against infection.

Research projects will encompass various tasks such as:

• Chemical synthesis
• In vitro antimicrobial activity testing
• Understanding mechanisms of action
• In vivo efficacy evaluation.

The candidate will be trained on project management and ideation of new studies aligning with the lab focus. They will also support the team in lab operation, safety oversight, and documenting experimental procedures and results.

Job Requirements

• Ph.D degree in microbiology, biomedical science, bioengineering, or any other related field
• Having background knowledge in AI and programming will be an advantage
• Highly motivated and passionate about scientific research
• Effective communication both verbally and in writing
• Team player
• Receptive and detail-orientated

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

A*STAR Infectious Diseases Labs (A*IDL) is seeking for a Research Scientist to join us in our mission to to be a leading centre for infectious diseases research excellence in antimicrobial resistance, respiratory and vector-borne diseases. A*ID Labs brings together infectious diseases expertise from across multiple disciplines to drive cutting edge translational infectious diseases research to contribute to Singapore’s national preparedness.

You will be joining the Mucosal Infection Lab. The lab focuses on modelling mucosal infection using in vitro and in vivo systems with priority antimicrobial resistance (AMR) bacteria to understand disease pathogenesis. Specifically, the projects will involve dissecting the mechanisms in the gut-liver axis during bacterial induced pyrogenic liver abscess. Candidates with prior experience working with liver diseases and single-cell RNAseq are preferred.

Job Responsibilities:

• Basic molecular and protein assay including PCR and ELISA
• Small animal infection with AMR bacteria (Klebsiella pneumoniae and E. coli)
• Small animal microbiome colonization models
• In vitro infection assay using AMR bacteria and microbiome.
• Immune profiling in the tissues of infected animals
• Lab safety and housekeeping
• Routine administrative duties and budget/spending management of the lab

Job Requirements:

• PhD in Biomedical Sciences, Life Sciences, Infectious diseases, Immunology or related field.
• At least 1 year of relevant experience
• Good spoken and written communication skills
• Experience working with liver diseases
• Background with single cell RNAseq
• Competency in bacterial culture, cell culture, flow cytometry and basic microscopy will be advantageous but not strictly required.
• Basic knowledge in bioinformatics will be advantageous.
• Comfortable working with small animal models

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.

Duties and Responsibilities - Process Integration

• Plan the integration flow with device designers
• Draft the runsheet by translating the flow into process steps and capturing necessary shortloops
• Perform the DoE with process module teams
• Track the lot and report the progress
• Identify failure modes/root causes and address the problems by proposing changes
• Must be good at documentation and written communication

Job Requirements

• Bachelor's degree in Microelectronics, Electrical, Mechanical, or Chemical Engineering.
• A basic understanding of the semiconductor processes is preferred.
• 3-5 years of hands-on experience in semiconductor processes (Diffusion, Wet Clean, CMP, ECP, Litho, Etch, CVD, PVD, etc.) will add advantages.
• Must be a team worker with the project stakeholders (device design, process module, and equipment/facility).

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Responsibilities

The lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.

The work will involve both in vitro and in vivo techniques, including molecular biology (RNA design, in vitro transcription, cell-free RNA assays, RT-qPCR, molecular cloning), cell biology (cell culture, cell transfection, flow cytometry, antisense oligonucleotides and RNAi, CRISPR), high-resolution imaging techniques, and experiments in mouse models (e.g. transgenesis, in situ hybridization and immunohistochemistry, imaging and functional analyses)

Requirements

• Minimum Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Genetics, Neuroscience or a related discipline.
• The successful candidate should have strong expertise in RNA biology, cell biology, biochemistry and molecular biology techniques, a strong publication record that includes a first author research paper, and strong scientific writing skills.
• They should be creative, highly motivated, conscientious and be able to work independently, with good organisational, verbal and interpersonal skills. Our lab is collaborative and interdisciplinary, and the successful candidate should be able to work effectively and harmoniously in a diverse team.
• As a Scientist, candidate will also be expected to mentor and train students and Research Officers.

Job Description

A scientist or senior scientist position is available at the Functional Proteomics Laboratory for setting up, developing methods and performing targeted and untargeted metabolomics experiments. You will work on mass spectrometry-based identification of small molecule binders of RNA and small molecule metabolomics projects.

• Develop and run standardized protocols for untargeted metabolomics (or targeted metabolomics panels) for small molecule analysis.
• Design workflows and optimize analytical methods for performing targeted/untargeted metabolomics experiments for different sample mediums (Plasma/Urine/Tissue).
• Work with different collaborators and lead projects for small molecule metabolomics analysis on various sample types.
• Conceptualise, design and develop metabolomics assays for quantification of small molecules.
• Write and present research findings for conferences and publications.
• Contribute to project management, provision of guidance to junior researchers, including research officers.

Job Requirements

• Ph.D. degree in Molecular Biology, Biochemistry, Chemical Biology, Analytical Chemistry or a related discipline.
• Strong expertise in small molecule mass spectrometry metabolomics (preferred untargeted small molecule metabolomics expertise) with good publication record.
• Experience with liquid chromatography and mass spectrometry instrumentation, sample preparation techniques, data acquisition and interpretation.
• At least 2 years working experience in the field of metabolomics will be preferred.
• Proficiency in data processing, data analysis and interpretation will be advantageous.
• Responsible, organized, able to work independently and with a team.
• Good communication skills for scientific presentation and scientific writing.
• Optional: Prior experience with R or other data analysis tools

Postdoctoral Scientist position

A postdoctoral scientist position is available immediately in the laboratory of Dr. Leslie Beh at IMCB.

The Beh lab seeks to develop cutting-edge CRISPR-Cas technologies to uncover the biological functions of RNA modifications. Dysregulation of these modifications has been linked to cancer, neurological disorders, and metabolic disease. We will determine the mechanisms by which RNA modifications and CRISPR-Cas systems operate by drawing upon diverse techniques, including protein engineering, biochemical reconstitution, genomics, and cell-based experiments. Successful applicants can expect close mentorship in a collaborative environment, with an emphasis on developing scientific knowledge and individual career goals. More information about can be found at (https://www.behlab.org/).

Requirements:

• Ph.D. in Life Sciences / Biomedical Sciences
• Experience in biochemistry and/or structural biology, particularly in protein-RNA or protein-DNA interactions.
• in vitro reconstitution of enzymatic activity using cell extracts or purified proteins
• Recombinant protein purification from bacterial and insect cells
• Genuine interest in pursuing a research-based career.
• Strong work ethic, with excellent organizational and communication skills

Preferred experience:

• Mammalian cell culture
• NGS library generation and data analysis
• Prior roles in lab management