Job Description:
We are seeking a highly skilled and motivated Research Officer specializing in AI and spatial multi-omics to join our cutting-edge research team. This role focuses on advancing cancer immunotherapy (IO) for Asian-prevalent tumors through the integration of Generative AI techniques and spatial multi-omics data analysis. This position offers a unique opportunity to address critical challenges in immunotherapy, such as the identification of effective biomarkers and an in-depth understanding of the tumor microenvironment.
Key Responsibilities:
1. Multi-Omics-IO Classifier Development: Develop and validate a classifier to integrate IO biomarkers identified from the multi-omics analyses, benchmarked against conventional markers (e.g., PD-1/PD-L1).
2. AI Model Development: Create AI models for virtual staining to visualize gene expression and multi-omics biomarkers.
3. Collaboration & Reporting: Collaborate with pathologists, immunologists, and AI researchers to ensure robust, clinically relevant model development. Prepare reports, presentations, and manuscripts for publication.
Requirements:
- Bachelor degree in AI/ML, or a related field with a strong focus on imaging and deep learning.
- Technical Skills: Expertise in AI techniques and experience in omics data analysis.
- Strong programming skills in Python or R, with experience in deep learning frameworks (e.g., PyTorch, TensorFlow).
- Domain Knowledge: Familiarity with cancer immunotherapy and biomarker development.
- Analytical Skills: Proven experience in developing and evaluating complex machine learning models, especially for biomarker discovery and clinical applications.
- Collaboration & Communication: Excellent interpersonal and communication skills to work effectively within a multidisciplinary team of scientists, clinicians, and technical staff.
- Preferably with experience with virtual staining, explainable AI, and histopathological analysis. A track record of publications in high-impact journals and presentations at scientific conferences. Prior experience in developing and applying AI models in healthcare or clinical settings is a plus.
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.